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GILD vs. INSM: Gilead Sciences vs. Insmed Stock Comparison

How do Gilead Sciences (GILD) and Insmed (INSM) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Gilead Sciences (GILD) and Insmed (INSM) are both classified in the Biotechnology sub-industry within the broader Biotechnology industry, placing them in the closest GICS peer bucket.

Company profile comparison for Gilead Sciences (GILD) and Insmed (INSM)
Profile ItemGILDINSM
NameGilead Sciences Inc.Insmed Incorporated
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyBiotechnology
GICS Sub-IndustryBiotechnologyBiotechnology
Market Capitalization207.00 billion USD25.10 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateJanuary 22, 1992June 1, 2000
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

GILD
INSM
GSPC
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Gilead Sciences (GILD) vs. Insmed (INSM), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Gilead Sciences (GILD) and Insmed (INSM). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Gilead Sciences (GILD) and Insmed (INSM). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Gilead Sciences (GILD) and Insmed (INSM)
MetricGILDINSM
Total Return (1Y)45.69%-39.17%
Total Return (3Y, Annualized)35.30%70.17%
Total Return (5Y, Annualized)25.00%28.96%

Risk Profile

Drawdown History

GILD
INSM
GSPC
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Gilead Sciences (GILD) vs. Insmed (INSM), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Gilead Sciences (GILD) and Insmed (INSM). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Gilead Sciences (GILD) and Insmed (INSM)
MetricGILDINSM
Volatility (1Y, Annualized)27.57%63.09%
Beta (5Y)0.360.80
Max Drawdown (5Y)-26.59%-56.54%
Avg. Volume (3M)5.98M2.76M

Risk-Adjusted Performance

Risk-Return Positioning

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GILD and INSM are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Gilead Sciences (GILD) and Insmed (INSM)
MetricGILDINSM
Sharpe Ratio (1Y)1.50-0.69
Sortino Ratio (1Y)2.48-1.04

Profitability

ROE (TTM)

Both Gilead Sciences (GILD) at -22.45% and Insmed (INSM) at -72.45% report negative ROE values. Negative ROE can reflect losses or negative shareholders’ equity, so both readings need extra context.

GILD

Pharmaceuticals, Biotechnology & Life Sciences industry group

-22.45%

Max
109.18%
Q3
6.23%
GILD
-22.45%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-72.45%

Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
INSM
-72.45%
Min
-167.77%
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Gilead Sciences (GILD) vs. Insmed (INSM): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Both Gilead Sciences (GILD) at -12.46% and Insmed (INSM) at -39.85% report negative net margin values, usually indicating net losses over the period.

GILD

Pharmaceuticals, Biotechnology & Life Sciences industry group

-12.46%

Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
GILD
-12.46%
Min
-17.05%

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-39.85%

Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
INSM
-39.85%
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Gilead Sciences (GILD) vs. Insmed (INSM): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Insmed (INSM) reports a negative operating margin of -15.60%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Gilead Sciences (GILD) reports 42.43%, ranking against industry peers normally.

GILD

Pharmaceuticals, Biotechnology & Life Sciences industry group

42.43%

Max
83.12%
GILD
42.43%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-15.60%

Max
83.12%
Q3
14.77%
Median
0.00%
INSM
-15.60%
Q1
-78.82%
Min
-207.40%
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Gilead Sciences (GILD) vs. Insmed (INSM): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Gilead Sciences (GILD) and Insmed (INSM)
MetricGILDINSM
ROE (TTM)-22.45%-72.45%
ROA (TTM)13.47%-17.25%
Net Margin (TTM)-12.46%-39.85%
Operating Margin (TTM)42.43%-15.60%
Gross Margin (TTM)79.95%84.40%

Growth

Revenue Growth

Insmed (INSM) at 66.73% sits in the top revenue growth quartile, while Gilead Sciences (GILD) at 2.39% is closer to the peer norm — faster top-line expansion for INSM.

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Gilead Sciences (GILD) vs. Insmed (INSM): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Gilead Sciences (GILD) reports EPS growth of 1,684.21%, ranked against its industry; Insmed (INSM) has no EPS growth figure this period.

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Gilead Sciences (GILD) vs. Insmed (INSM): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Gilead Sciences (GILD) and Insmed (INSM)
MetricGILDINSM
Revenue Growth (YoY)2.39%66.73%
Revenue Growth (3Y CAGR)2.57%35.20%
EPS Growth (YoY)1,684.21%--
EPS Growth (3Y CAGR)23.04%--

Financial Strength

Current Ratio (MRQ)

Insmed (INSM) at 2.86 keeps current ratio within its industry’s typical mid-range, while Gilead Sciences (GILD) at 1.38 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for GILD.

GILD

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.38

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
GILD
1.38
Min
0.10

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.86

Max
25.13
Q3
12.13
Median
5.52
INSM
2.86
Q1
2.47
Min
0.10
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Gilead Sciences (GILD) vs. Insmed (INSM): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both balance sheets lean debt-heavy versus peers, but GILD is more stretched: Insmed (INSM) at 1.01 sits in the higher-leverage quartile and Gilead Sciences (GILD) at 2.02 is above its industry benchmark range.

GILD

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.02

GILD
2.02
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.01

Max
1.42
INSM
1.01
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Gilead Sciences (GILD) vs. Insmed (INSM): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Gilead Sciences (GILD) and Insmed (INSM)
MetricGILDINSM
Current Ratio (MRQ)1.382.86
Debt / Equity (MRQ)2.021.01
Net Debt / EBITDA1.25--

Dividends

Dividend Yield (TTM)

Insmed (INSM) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Gilead Sciences (GILD) reports a yield of 1.94%, ranking against industry peers normally.

GILD

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.94%

GILD
1.94%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

INSM
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Gilead Sciences (GILD) vs. Insmed (INSM): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Insmed (INSM) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Gilead Sciences (GILD) reports a payout of 43.46%, ranking against industry peers normally.

GILD

Pharmaceuticals, Biotechnology & Life Sciences industry group

43.46%

GILD
43.46%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

INSM
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Gilead Sciences (GILD) vs. Insmed (INSM): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Gilead Sciences (GILD) and Insmed (INSM)
MetricGILDINSM
Dividend Yield (TTM)1.94%0.00%
Dividend Payout Ratio (TTM)43.46%0.00%

Valuation

P/E Ratio (TTM)

Neither Gilead Sciences (GILD) nor Insmed (INSM) reports a P/E ratio value for this period, so a direct comparison isn’t possible.

GILD

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
GILD
--

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
INSM
--
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Gilead Sciences (GILD) vs. Insmed (INSM): Neither stock reports P/E ratio, so the chart shows available benchmark boxes without value markers.

P/S Ratio (TTM)

On P/S ratio, both Gilead Sciences (GILD) at 6.68 and Insmed (INSM) at 16.52 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

GILD

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.68

Max
58.18
Q3
25.77
Median
7.30
GILD
6.68
Q1
3.01
Min
0.01

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

16.52

Max
58.18
Q3
25.77
INSM
16.52
Median
7.30
Q1
3.01
Min
0.01
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Gilead Sciences (GILD) vs. Insmed (INSM): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Measured against book value, both Gilead Sciences (GILD) at 15.88 and Insmed (INSM) at 34.55 look expensive — each P/B ratio sits above its industry’s benchmark range.

GILD

Pharmaceuticals, Biotechnology & Life Sciences industry group

15.88

GILD
15.88
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

34.55

INSM
34.55
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Gilead Sciences (GILD) vs. Insmed (INSM): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Gilead Sciences (GILD) and Insmed (INSM)
MetricGILDINSM
P/E Ratio (TTM)----
P/S Ratio (TTM)6.6816.52
P/B Ratio (MRQ)15.8834.55
Free Cash Flow Yield (TTM)5.16%-1.82%