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EXEL vs. RVMD: Exelixis vs. Revolution Medicines Stock Comparison

How do Exelixis (EXEL) and Revolution Medicines (RVMD) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Exelixis (EXEL) and Revolution Medicines (RVMD) are both classified in the Biotechnology sub-industry within the broader Biotechnology industry, placing them in the closest GICS peer bucket.

Exelixis (EXEL) has more than two decades of public-market history since April 17, 2000, whereas Revolution Medicines (RVMD) listed on February 13, 2020 and has a much shorter record to draw on.

Company profile comparison for Exelixis (EXEL) and Revolution Medicines (RVMD)
Profile ItemEXELRVMD
NameExelixis Inc.Revolution Medicines, Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyBiotechnology
GICS Sub-IndustryBiotechnologyBiotechnology
Market Capitalization16.98 billion USD41.59 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateApril 17, 2000February 13, 2020
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

EXEL
RVMD
GSPC
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Exelixis (EXEL) vs. Revolution Medicines (RVMD), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Exelixis (EXEL) and Revolution Medicines (RVMD). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Exelixis (EXEL) and Revolution Medicines (RVMD). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Exelixis (EXEL) and Revolution Medicines (RVMD)
MetricEXELRVMD
Total Return (1Y)74.98%224.80%
Total Return (3Y, Annualized)50.33%114.71%
Total Return (5Y, Annualized)31.10%43.47%

Risk Profile

Drawdown History

EXEL
RVMD
GSPC
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Exelixis (EXEL) vs. Revolution Medicines (RVMD), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Exelixis (EXEL) and Revolution Medicines (RVMD). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Revolution Medicines (RVMD) has an aggressive beta of 1.42, indicating higher sensitivity to broad-market moves, while Exelixis (EXEL) is defensive at 0.41 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Exelixis (EXEL) and Revolution Medicines (RVMD)
MetricEXELRVMD
Volatility (1Y, Annualized)34.17%68.29%
Beta (5Y)0.411.42
Max Drawdown (5Y)-35.41%-55.71%
Avg. Volume (3M)2.33M2.06M

Risk-Adjusted Performance

Risk-Return Positioning

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EXEL and RVMD are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Exelixis (EXEL) and Revolution Medicines (RVMD)
MetricEXELRVMD
Sharpe Ratio (1Y)2.073.23
Sortino Ratio (1Y)3.236.92

Profitability

ROE (TTM)

Revolution Medicines (RVMD) reports a negative ROE of -93.56%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Exelixis (EXEL) reports 44.32%, ranking against industry peers normally.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

44.32%

Max
109.18%
EXEL
44.32%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

-93.56%

Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
RVMD
-93.56%
Min
-167.77%
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Exelixis (EXEL) vs. Revolution Medicines (RVMD): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Exelixis (EXEL) at 35.45% converts revenue to bottom-line profit above its industry’s benchmark range, while Revolution Medicines (RVMD) at 0.00% keeps roughly the typical share for its industry.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.45%

EXEL
35.45%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

Max
18.05%
Q3
4.78%
RVMD
0.00%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Exelixis (EXEL) vs. Revolution Medicines (RVMD): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Revolution Medicines (RVMD) reports a negative operating margin of -188.88%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Exelixis (EXEL) reports 40.75%, ranking against industry peers normally.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

40.75%

Max
83.12%
EXEL
40.75%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

-188.88%

Max
83.12%
Q3
14.77%
Median
0.00%
Q1
-78.82%
RVMD
-188.88%
Min
-207.40%
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Exelixis (EXEL) vs. Revolution Medicines (RVMD): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Exelixis (EXEL) and Revolution Medicines (RVMD)
MetricEXELRVMD
ROE (TTM)44.32%-93.56%
ROA (TTM)23.52%-32.13%
Net Margin (TTM)35.45%0.00%
Operating Margin (TTM)40.75%-188.88%
Gross Margin (TTM)96.26%0.00%

Growth

Revenue Growth

Only one side can be read here: Exelixis (EXEL) reports revenue growth of 6.98%, ranked against its industry; Revolution Medicines (RVMD) has no revenue growth figure this period.

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Exelixis (EXEL) vs. Revolution Medicines (RVMD): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Exelixis (EXEL) reports EPS growth of 57.95%, ranked against its industry; Revolution Medicines (RVMD) has no EPS growth figure this period.

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Exelixis (EXEL) vs. Revolution Medicines (RVMD): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Exelixis (EXEL) and Revolution Medicines (RVMD)
MetricEXELRVMD
Revenue Growth (YoY)6.98%--
Revenue Growth (3Y CAGR)12.93%--
EPS Growth (YoY)57.95%--
EPS Growth (3Y CAGR)70.59%--

Financial Strength

Current Ratio (MRQ)

Both Exelixis (EXEL) at 3.21 and Revolution Medicines (RVMD) at 8.36 carry current ratio within their industries’ typical mid-ranges, suggesting balanced short-term liquidity relative to peers.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.21

Max
25.13
Q3
12.13
Median
5.52
EXEL
3.21
Q1
2.47
Min
0.10

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.36

Max
25.13
Q3
12.13
RVMD
8.36
Median
5.52
Q1
2.47
Min
0.10
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Exelixis (EXEL) vs. Revolution Medicines (RVMD): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both Exelixis (EXEL) at 0.09 and Revolution Medicines (RVMD) at 0.50 fund their balance sheets with roughly industry-typical debt-to-equity mixes.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.09

Max
1.42
Q3
0.65
Median
0.15
EXEL
0.09
Q1
0.02
Min
0.00

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.50

Max
1.42
Q3
0.65
RVMD
0.50
Median
0.15
Q1
0.02
Min
0.00
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Exelixis (EXEL) vs. Revolution Medicines (RVMD): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Exelixis (EXEL) and Revolution Medicines (RVMD)
MetricEXELRVMD
Current Ratio (MRQ)3.218.36
Debt / Equity (MRQ)0.090.50
Net Debt / EBITDA-0.71--

Dividends

Dividend Yield (TTM)

Neither Exelixis (EXEL) nor Revolution Medicines (RVMD) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

EXEL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RVMD
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Exelixis (EXEL) vs. Revolution Medicines (RVMD): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Exelixis (EXEL) nor Revolution Medicines (RVMD) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

EXEL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RVMD
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Exelixis (EXEL) vs. Revolution Medicines (RVMD): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Exelixis (EXEL) and Revolution Medicines (RVMD)
MetricEXELRVMD
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Exelixis (EXEL) trades at 20.83 times trailing earnings, ranked against its peers, while Revolution Medicines (RVMD) has no P/E ratio this period.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.83

Max
85.34
Q3
43.46
Median
26.69
EXEL
20.83
Q1
13.30
Min
0.07

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
RVMD
--
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Exelixis (EXEL) vs. Revolution Medicines (RVMD): RVMD does not report P/E ratio, so it has no value marker; EXEL is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

Exelixis (EXEL) at 6.80 prices around its industry’s typical P/S ratio, while Revolution Medicines (RVMD) at 210.51 clears its benchmark range — RVMD looks notably rich on sales.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.80

Max
58.18
Q3
25.77
Median
7.30
EXEL
6.80
Q1
3.01
Min
0.01

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

210.51

RVMD
210.51
Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
Min
0.01
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Exelixis (EXEL) vs. Revolution Medicines (RVMD): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Both look rich against book: Exelixis (EXEL) at 9.28 sits in the upper P/B ratio quartile, and Revolution Medicines (RVMD) at 17.31 prices even higher, above its industry range.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.28

Max
13.53
EXEL
9.28
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.31

RVMD
17.31
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Exelixis (EXEL) vs. Revolution Medicines (RVMD): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Exelixis (EXEL) and Revolution Medicines (RVMD)
MetricEXELRVMD
P/E Ratio (TTM)20.83--
P/S Ratio (TTM)6.80210.51
P/B Ratio (MRQ)9.2817.31
Free Cash Flow Yield (TTM)4.47%-2.13%