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EXEL vs. JAZZ: Exelixis vs. Jazz Pharmaceuticals Stock Comparison

How do Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but EXEL is classified in Biotechnology while JAZZ is classified in Pharmaceuticals.

Company profile comparison for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ)
Profile ItemEXELJAZZ
NameExelixis Inc.Jazz Pharmaceuticals plc
Country/RegionUnited StatesIreland
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization16.98 billion USD15.07 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateApril 17, 2000June 1, 2007
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

EXEL
JAZZ
GSPC
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ)
MetricEXELJAZZ
Total Return (1Y)74.98%84.44%
Total Return (3Y, Annualized)50.33%27.57%
Total Return (5Y, Annualized)31.10%12.88%

Risk Profile

Drawdown History

EXEL
JAZZ
GSPC
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ)
MetricEXELJAZZ
Volatility (1Y, Annualized)34.17%38.74%
Beta (5Y)0.410.33
Max Drawdown (5Y)-35.41%-42.03%
Avg. Volume (3M)2.33M878.80K

Risk-Adjusted Performance

Risk-Return Positioning

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EXEL and JAZZ are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ)
MetricEXELJAZZ
Sharpe Ratio (1Y)2.072.07
Sortino Ratio (1Y)3.234.14

Profitability

ROE (TTM)

Exelixis (EXEL) at 44.32% sits in the top ROE quartile, while Jazz Pharmaceuticals (JAZZ) at 5.05% is closer to the peer norm — stronger capital efficiency for EXEL.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

44.32%

Max
109.18%
EXEL
44.32%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.05%

Max
109.18%
Q3
6.23%
JAZZ
5.05%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Exelixis (EXEL) at 35.45% converts revenue to bottom-line profit above its industry’s benchmark range, while Jazz Pharmaceuticals (JAZZ) at 4.37% keeps roughly the typical share for its industry.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.45%

EXEL
35.45%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.37%

Max
18.05%
Q3
4.78%
JAZZ
4.37%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Exelixis (EXEL) at 40.75% and Jazz Pharmaceuticals (JAZZ) at 30.17% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

40.75%

Max
83.12%
EXEL
40.75%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

30.17%

Max
83.12%
JAZZ
30.17%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ)
MetricEXELJAZZ
ROE (TTM)44.32%5.05%
ROA (TTM)23.52%6.92%
Net Margin (TTM)35.45%4.37%
Operating Margin (TTM)40.75%30.17%
Gross Margin (TTM)96.26%91.10%

Growth

Revenue Growth

Both Exelixis (EXEL) at 6.98% and Jazz Pharmaceuticals (JAZZ) at 4.88% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their Revenue Growth across different time periods.

EPS Growth

Exelixis (EXEL) at 57.95% is around its peer norm for EPS growth, while Jazz Pharmaceuticals (JAZZ) at -167.51% drops into the bottom quartile, signaling weaker earnings momentum.

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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ)
MetricEXELJAZZ
Revenue Growth (YoY)6.98%4.88%
Revenue Growth (3Y CAGR)12.93%5.26%
EPS Growth (YoY)57.95%-167.51%
EPS Growth (3Y CAGR)70.59%--

Financial Strength

Current Ratio (MRQ)

Exelixis (EXEL) at 3.21 keeps current ratio within its industry’s typical mid-range, while Jazz Pharmaceuticals (JAZZ) at 1.82 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for JAZZ.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.21

Max
25.13
Q3
12.13
Median
5.52
EXEL
3.21
Q1
2.47
Min
0.10

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.82

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
JAZZ
1.82
Min
0.10
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Exelixis (EXEL) at 0.09 carries an industry-typical debt-to-equity mix, while Jazz Pharmaceuticals (JAZZ) at 1.35 uses more debt funding than most peers.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.09

Max
1.42
Q3
0.65
Median
0.15
EXEL
0.09
Q1
0.02
Min
0.00

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.35

Max
1.42
JAZZ
1.35
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ)
MetricEXELJAZZ
Current Ratio (MRQ)3.211.82
Debt / Equity (MRQ)0.091.35
Net Debt / EBITDA-0.711.39

Dividends

Dividend Yield (TTM)

Neither Exelixis (EXEL) nor Jazz Pharmaceuticals (JAZZ) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

EXEL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

JAZZ
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Exelixis (EXEL) nor Jazz Pharmaceuticals (JAZZ) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

EXEL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

JAZZ
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ)
MetricEXELJAZZ
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

Exelixis (EXEL) at 20.83 is near its industry’s usual P/E ratio, while Jazz Pharmaceuticals (JAZZ) at 69.46 sits in the richer quartile — JAZZ needs stronger growth or earnings quality to justify the premium.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.83

Max
85.34
Q3
43.46
Median
26.69
EXEL
20.83
Q1
13.30
Min
0.07

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

69.46

Max
85.34
JAZZ
69.46
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Exelixis (EXEL) at 6.80 and Jazz Pharmaceuticals (JAZZ) at 3.19 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.80

Max
58.18
Q3
25.77
Median
7.30
EXEL
6.80
Q1
3.01
Min
0.01

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.19

Max
58.18
Q3
25.77
Median
7.30
JAZZ
3.19
Q1
3.01
Min
0.01
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Jazz Pharmaceuticals (JAZZ) at 3.59 is valued about in line with its industry on P/B ratio, while Exelixis (EXEL) at 9.28 carries an above-peer premium to book — EXEL is pricier on assets.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.28

Max
13.53
EXEL
9.28
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.59

Max
13.53
Q3
6.54
JAZZ
3.59
Median
3.25
Q1
1.69
Min
-5.59
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Exelixis (EXEL) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Exelixis (EXEL) and Jazz Pharmaceuticals (JAZZ)
MetricEXELJAZZ
P/E Ratio (TTM)20.8369.46
P/S Ratio (TTM)6.803.19
P/B Ratio (MRQ)9.283.59
Free Cash Flow Yield (TTM)4.47%11.16%