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EXEL vs. GSK: Exelixis vs. GSK Stock Comparison

How do Exelixis (EXEL) and GSK (GSK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Exelixis (EXEL) and GSK (GSK) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but EXEL is classified in Biotechnology while GSK is classified in Pharmaceuticals.

Exelixis (EXEL) trades as ordinary local shares, while GSK (GSK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for Exelixis (EXEL) and GSK (GSK)
Profile ItemEXELGSK
NameExelixis Inc.GSK plc ADR
Country/RegionUnited StatesUnited Kingdom
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization16.98 billion USD100.88 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateApril 17, 2000March 28, 1980
Security TypeCommon StockADR

Price Performance

Cumulative Growth

EXEL
GSK
GSPC
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Exelixis (EXEL) vs. GSK (GSK), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Exelixis (EXEL) and GSK (GSK). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Exelixis (EXEL) and GSK (GSK). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Exelixis (EXEL) and GSK (GSK)
MetricEXELGSK
Total Return (1Y)74.98%13.73%
Total Return (3Y, Annualized)50.33%18.65%
Total Return (5Y, Annualized)31.10%7.97%

Risk Profile

Drawdown History

EXEL
GSK
GSPC
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Exelixis (EXEL) vs. GSK (GSK), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Exelixis (EXEL) and GSK (GSK). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Exelixis (EXEL) and GSK (GSK)
MetricEXELGSK
Volatility (1Y, Annualized)34.17%26.25%
Beta (5Y)0.410.31
Max Drawdown (5Y)-35.41%-37.63%
Avg. Volume (3M)2.33M4.05M

Risk-Adjusted Performance

Risk-Return Positioning

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EXEL and GSK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Exelixis (EXEL) and GSK (GSK)
MetricEXELGSK
Sharpe Ratio (1Y)2.070.36
Sortino Ratio (1Y)3.230.56

Profitability

ROE (TTM)

Both Exelixis (EXEL) at 44.32% and GSK (GSK) at 28.27% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

44.32%

Max
109.18%
EXEL
44.32%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.27%

Max
109.18%
GSK
28.27%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Exelixis (EXEL) vs. GSK (GSK): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Exelixis (EXEL) at 35.45% keeps the most of each sales dollar — above its industry’s net margin range — and GSK (GSK) at 12.97% also retains a top-quartile share.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.45%

EXEL
35.45%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

12.97%

Max
18.05%
GSK
12.97%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Exelixis (EXEL) vs. GSK (GSK): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Exelixis (EXEL) at 40.75% and GSK (GSK) at 32.14% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

40.75%

Max
83.12%
EXEL
40.75%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.14%

Max
83.12%
GSK
32.14%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Exelixis (EXEL) vs. GSK (GSK): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Exelixis (EXEL) and GSK (GSK)
MetricEXELGSK
ROE (TTM)44.32%28.27%
ROA (TTM)23.52%9.24%
Net Margin (TTM)35.45%12.97%
Operating Margin (TTM)40.75%32.14%
Gross Margin (TTM)96.26%73.79%

Growth

Revenue Growth

Both Exelixis (EXEL) at 6.98% and GSK (GSK) at 4.11% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Exelixis (EXEL) vs. GSK (GSK): A comparison of their Revenue Growth across different time periods.

EPS Growth

GSK (GSK) at 123.15% sits in the top EPS growth quartile, while Exelixis (EXEL) at 57.95% is closer to the peer norm — faster per-share earnings growth for GSK.

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Exelixis (EXEL) vs. GSK (GSK): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Exelixis (EXEL) and GSK (GSK)
MetricEXELGSK
Revenue Growth (YoY)6.98%4.11%
Revenue Growth (3Y CAGR)12.93%3.66%
EPS Growth (YoY)57.95%123.15%
EPS Growth (3Y CAGR)70.59%-27.63%

Financial Strength

Current Ratio (MRQ)

Exelixis (EXEL) at 3.21 keeps current ratio within its industry’s typical mid-range, while GSK (GSK) at 0.86 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for GSK.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.21

Max
25.13
Q3
12.13
Median
5.52
EXEL
3.21
Q1
2.47
Min
0.10

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.86

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
GSK
0.86
Min
0.10
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Exelixis (EXEL) vs. GSK (GSK): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Exelixis (EXEL) at 0.09 carries an industry-typical debt-to-equity mix, while GSK (GSK) at 1.30 uses more debt funding than most peers.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.09

Max
1.42
Q3
0.65
Median
0.15
EXEL
0.09
Q1
0.02
Min
0.00

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.30

Max
1.42
GSK
1.30
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Exelixis (EXEL) vs. GSK (GSK): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Exelixis (EXEL) and GSK (GSK)
MetricEXELGSK
Current Ratio (MRQ)3.210.86
Debt / Equity (MRQ)0.091.30
Net Debt / EBITDA-0.711.88

Dividends

Dividend Yield (TTM)

Exelixis (EXEL) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile GSK (GSK) reports a yield of 1.57%, ranking against industry peers normally.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

EXEL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.57%

GSK
1.57%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Exelixis (EXEL) vs. GSK (GSK): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Exelixis (EXEL) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile GSK (GSK) reports a payout of 63.33%, ranking against industry peers normally.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

EXEL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

63.33%

GSK
63.33%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Exelixis (EXEL) vs. GSK (GSK): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Exelixis (EXEL) and GSK (GSK)
MetricEXELGSK
Dividend Yield (TTM)0.00%1.57%
Dividend Payout Ratio (TTM)0.00%63.33%

Valuation

P/E Ratio (TTM)

Both Exelixis (EXEL) at 20.83 and GSK (GSK) at 17.54 land around their industries’ usual P/E ratio levels — neither is getting a clear earnings-multiple discount or premium versus peers.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.83

Max
85.34
Q3
43.46
Median
26.69
EXEL
20.83
Q1
13.30
Min
0.07

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.54

Max
85.34
Q3
43.46
Median
26.69
GSK
17.54
Q1
13.30
Min
0.07
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Exelixis (EXEL) vs. GSK (GSK): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

GSK (GSK) at 3.01 sits in the cheaper P/S ratio quartile while Exelixis (EXEL) at 6.80 prices around its industry’s middle — GSK costs less per dollar of sales, though read it alongside growth and margins.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.80

Max
58.18
Q3
25.77
Median
7.30
EXEL
6.80
Q1
3.01
Min
0.01

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
GSK
3.01
Min
0.01
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Exelixis (EXEL) vs. GSK (GSK): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

GSK (GSK) at 4.02 is valued about in line with its industry on P/B ratio, while Exelixis (EXEL) at 9.28 carries an above-peer premium to book — EXEL is pricier on assets.

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.28

Max
13.53
EXEL
9.28
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.02

Max
13.53
Q3
6.54
GSK
4.02
Median
3.25
Q1
1.69
Min
-5.59
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Exelixis (EXEL) vs. GSK (GSK): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Exelixis (EXEL) and GSK (GSK)
MetricEXELGSK
P/E Ratio (TTM)20.8317.54
P/S Ratio (TTM)6.803.01
P/B Ratio (MRQ)9.284.02
Free Cash Flow Yield (TTM)4.47%5.28%