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CRL vs. SMMT: Charles River Laboratories vs. Summit Therapeutics Stock Comparison

How do Charles River Laboratories (CRL) and Summit Therapeutics (SMMT) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Charles River Laboratories (CRL) and Summit Therapeutics (SMMT) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but CRL is classified in Life Sciences Tools & Services while SMMT is classified in Biotechnology.

Company profile comparison for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT)
Profile ItemCRLSMMT
NameCharles River Laboratories International, Inc.Summit Therapeutics Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesBiotechnology
GICS Sub-IndustryLife Sciences Tools & ServicesBiotechnology
Market Capitalization16.17 billion USD13.06 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateJune 23, 2000March 5, 2015
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

CRL
SMMT
GSPC
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT)
MetricCRLSMMT
Total Return (1Y)110.83%-2.48%
Total Return (3Y, Annualized)27.87%116.18%
Total Return (5Y, Annualized)-1.57%26.89%

Risk Profile

Drawdown History

CRL
SMMT
GSPC
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Summit Therapeutics (SMMT) reports a negative beta of -1.51, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Charles River Laboratories (CRL) has a non-negative beta of 1.33.

Risk profile metrics for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT)
MetricCRLSMMT
Volatility (1Y, Annualized)47.81%75.06%
Beta (5Y)1.33-1.51
Max Drawdown (5Y)-74.73%-87.64%
Avg. Volume (3M)1.05M6.19M

Risk-Adjusted Performance

Risk-Return Positioning

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CRL and SMMT are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT)
MetricCRLSMMT
Sharpe Ratio (1Y)2.23-0.09
Sortino Ratio (1Y)3.58-0.13

Profitability

ROE (TTM)

Summit Therapeutics (SMMT) reports a negative ROE of -220.01%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Charles River Laboratories (CRL) reports 1.27%, ranking against industry peers normally.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.27%

Max
109.18%
Q3
6.23%
CRL
1.27%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

-220.01%

Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
SMMT
-220.01%
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Both Charles River Laboratories (CRL) at 1.01% and Summit Therapeutics (SMMT) at 0.00% keep about the typical share of revenue as profit for their industries — neither bottom line stands out from peers.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.01%

Max
18.05%
Q3
4.78%
CRL
1.01%
Median
0.00%
Q1
-4.14%
Min
-17.05%

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

Max
18.05%
Q3
4.78%
SMMT
0.00%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Charles River Laboratories (CRL) at 23.42% operates in the top operating margin quartile, ahead of Summit Therapeutics (SMMT) at 0.00%, which runs around its industry’s norm.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.42%

Max
83.12%
CRL
23.42%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

Max
83.12%
Q3
14.77%
SMMT
0.00%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT)
MetricCRLSMMT
ROE (TTM)1.27%-220.01%
ROA (TTM)4.74%-111.99%
Net Margin (TTM)1.01%0.00%
Operating Margin (TTM)23.42%0.00%
Gross Margin (TTM)35.10%0.00%

Growth

Revenue Growth

Only one side can be read here: Charles River Laboratories (CRL) reports revenue growth of -0.85%, ranked against its industry; Summit Therapeutics (SMMT) has no revenue growth figure this period.

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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Charles River Laboratories (CRL) reports EPS growth of -1,555.00%, ranked against its industry; Summit Therapeutics (SMMT) has no EPS growth figure this period.

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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT)
MetricCRLSMMT
Revenue Growth (YoY)-0.85%--
Revenue Growth (3Y CAGR)0.33%--
EPS Growth (YoY)-1,555.00%--
EPS Growth (3Y CAGR)----

Financial Strength

Current Ratio (MRQ)

Summit Therapeutics (SMMT) at 5.99 keeps current ratio within its industry’s typical mid-range, while Charles River Laboratories (CRL) at 1.41 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for CRL.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.41

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
CRL
1.41
Min
0.10

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.99

Max
25.13
Q3
12.13
SMMT
5.99
Median
5.52
Q1
2.47
Min
0.10
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Summit Therapeutics (SMMT) at 0.04 carries an industry-typical debt-to-equity mix, while Charles River Laboratories (CRL) at 0.87 uses more debt funding than most peers.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87

Max
1.42
CRL
0.87
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.04

Max
1.42
Q3
0.65
Median
0.15
SMMT
0.04
Q1
0.02
Min
0.00
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT)
MetricCRLSMMT
Current Ratio (MRQ)1.415.99
Debt / Equity (MRQ)0.870.04
Net Debt / EBITDA2.92--

Dividends

Dividend Yield (TTM)

Neither Charles River Laboratories (CRL) nor Summit Therapeutics (SMMT) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

SMMT
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Charles River Laboratories (CRL) nor Summit Therapeutics (SMMT) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

SMMT
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT)
MetricCRLSMMT
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Charles River Laboratories (CRL) trades at 366.87 times trailing earnings, ranked against its peers, while Summit Therapeutics (SMMT) has no P/E ratio this period.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

366.87

CRL
366.87
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
SMMT
--
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): SMMT does not report P/E ratio, so it has no value marker; CRL is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

A sales-based read is only available for Charles River Laboratories (CRL), whose P/S ratio of 4.07 ranks against industry peers; Summit Therapeutics (SMMT) reports no figure this period.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.07

Max
58.18
Q3
25.77
Median
7.30
CRL
4.07
Q1
3.01
Min
0.01

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
Min
0.01
SMMT
--
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): SMMT does not report P/S ratio, so it has no value marker; CRL is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/B Ratio (MRQ)

Charles River Laboratories (CRL) at 5.01 sits near its industry’s typical P/B ratio, while Summit Therapeutics (SMMT) at 23.13 prices above its benchmark range — SMMT looks rich relative to book.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.01

Max
13.53
Q3
6.54
CRL
5.01
Median
3.25
Q1
1.69
Min
-5.59

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.13

SMMT
23.13
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Charles River Laboratories (CRL) vs. Summit Therapeutics (SMMT): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Charles River Laboratories (CRL) and Summit Therapeutics (SMMT)
MetricCRLSMMT
P/E Ratio (TTM)366.87--
P/S Ratio (TTM)4.07--
P/B Ratio (MRQ)5.0123.13
Free Cash Flow Yield (TTM)2.74%-1.64%