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CRL vs. MRK: Charles River Laboratories vs. Merck Stock Comparison

How do Charles River Laboratories (CRL) and Merck (MRK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Charles River Laboratories (CRL) and Merck (MRK) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but CRL is classified in Life Sciences Tools & Services while MRK is classified in Pharmaceuticals.

Company profile comparison for Charles River Laboratories (CRL) and Merck (MRK)
Profile ItemCRLMRK
NameCharles River Laboratories International, Inc.Merck & Co., Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesPharmaceuticals
GICS Sub-IndustryLife Sciences Tools & ServicesPharmaceuticals
Market Capitalization16.17 billion USD361.73 billion USD
CurrencyUSDUSD
ExchangeNYSENYSE
Listing DateJune 23, 2000January 2, 1962
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

CRL
MRK
GSPC
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Charles River Laboratories (CRL) vs. Merck (MRK), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Charles River Laboratories (CRL) and Merck (MRK). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Charles River Laboratories (CRL) and Merck (MRK). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Charles River Laboratories (CRL) and Merck (MRK)
MetricCRLMRK
Total Return (1Y)110.83%76.14%
Total Return (3Y, Annualized)27.87%16.48%
Total Return (5Y, Annualized)-1.57%15.77%

Risk Profile

Drawdown History

CRL
MRK
GSPC
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Charles River Laboratories (CRL) vs. Merck (MRK), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Charles River Laboratories (CRL) and Merck (MRK). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Charles River Laboratories (CRL) has an aggressive beta of 1.33, indicating higher sensitivity to broad-market moves, while Merck (MRK) is defensive at 0.11 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Charles River Laboratories (CRL) and Merck (MRK)
MetricCRLMRK
Volatility (1Y, Annualized)47.81%30.24%
Beta (5Y)1.330.11
Max Drawdown (5Y)-74.73%-43.44%
Avg. Volume (3M)1.05M10.24M

Risk-Adjusted Performance

Risk-Return Positioning

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CRL and MRK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Charles River Laboratories (CRL) and Merck (MRK)
MetricCRLMRK
Sharpe Ratio (1Y)2.232.38
Sortino Ratio (1Y)3.584.33

Profitability

ROE (TTM)

Both Charles River Laboratories (CRL) at 1.27% and Merck (MRK) at 5.06% land near their industries’ usual ROE ranges, so capital efficiency looks broadly in line with peers on both sides.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.27%

Max
109.18%
Q3
6.23%
CRL
1.27%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.06%

Max
109.18%
Q3
6.23%
MRK
5.06%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Both Charles River Laboratories (CRL) at 1.01% and Merck (MRK) at 3.64% keep about the typical share of revenue as profit for their industries — neither bottom line stands out from peers.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.01%

Max
18.05%
Q3
4.78%
CRL
1.01%
Median
0.00%
Q1
-4.14%
Min
-17.05%

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.64%

Max
18.05%
Q3
4.78%
MRK
3.64%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Charles River Laboratories (CRL) at 23.42% and Merck (MRK) at 35.22% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.42%

Max
83.12%
CRL
23.42%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.22%

Max
83.12%
MRK
35.22%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Charles River Laboratories (CRL) and Merck (MRK)
MetricCRLMRK
ROE (TTM)1.27%5.06%
ROA (TTM)4.74%11.29%
Net Margin (TTM)1.01%3.64%
Operating Margin (TTM)23.42%35.22%
Gross Margin (TTM)35.10%75.20%

Growth

Revenue Growth

Merck (MRK) at 1.31% is around its peer norm for revenue growth, while Charles River Laboratories (CRL) at -0.85% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their Revenue Growth across different time periods.

EPS Growth

Merck (MRK) at 8.01% is around its peer norm for EPS growth, while Charles River Laboratories (CRL) at -1,555.00% falls below its industry range, a notably weak earnings reading.

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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Charles River Laboratories (CRL) and Merck (MRK)
MetricCRLMRK
Revenue Growth (YoY)-0.85%1.31%
Revenue Growth (3Y CAGR)0.33%3.12%
EPS Growth (YoY)-1,555.00%8.01%
EPS Growth (3Y CAGR)--8.43%

Financial Strength

Current Ratio (MRQ)

Both Charles River Laboratories (CRL) at 1.41 and Merck (MRK) at 1.35 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.41

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
CRL
1.41
Min
0.10

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.35

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
MRK
1.35
Min
0.10
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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both Charles River Laboratories (CRL) at 0.87 and Merck (MRK) at 1.20 lean more heavily on debt funding than most peers, landing in the higher-leverage quartile of their industries.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87

Max
1.42
CRL
0.87
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.20

Max
1.42
MRK
1.20
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Charles River Laboratories (CRL) and Merck (MRK)
MetricCRLMRK
Current Ratio (MRQ)1.411.35
Debt / Equity (MRQ)0.871.20
Net Debt / EBITDA2.921.50

Dividends

Dividend Yield (TTM)

Charles River Laboratories (CRL) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Merck (MRK) reports a yield of 2.29%, ranking against industry peers normally.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.29%

MRK
2.29%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Merck (MRK) reports payout ratio above 100% at 343.43%, meaning dividends exceeded current-period earnings; Charles River Laboratories (CRL) pays no dividend (payout 0.00%).

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

343.43%

MRK
343.43%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Charles River Laboratories (CRL) and Merck (MRK)
MetricCRLMRK
Dividend Yield (TTM)0.00%2.29%
Dividend Payout Ratio (TTM)0.00%343.43%

Valuation

P/E Ratio (TTM)

Both Charles River Laboratories (CRL) at 366.87 and Merck (MRK) at 148.21 trade above their industries’ P/E ratio peer ranges, pointing to unusually expensive trailing earnings relative to peers.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

366.87

CRL
366.87
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

148.21

MRK
148.21
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Charles River Laboratories (CRL) at 4.07 and Merck (MRK) at 5.37 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.07

Max
58.18
Q3
25.77
Median
7.30
CRL
4.07
Q1
3.01
Min
0.01

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.37

Max
58.18
Q3
25.77
Median
7.30
MRK
5.37
Q1
3.01
Min
0.01
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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Charles River Laboratories (CRL) at 5.01 is valued about in line with its industry on P/B ratio, while Merck (MRK) at 8.06 carries an above-peer premium to book — MRK is pricier on assets.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.01

Max
13.53
Q3
6.54
CRL
5.01
Median
3.25
Q1
1.69
Min
-5.59

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.06

Max
13.53
MRK
8.06
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Charles River Laboratories (CRL) vs. Merck (MRK): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Charles River Laboratories (CRL) and Merck (MRK)
MetricCRLMRK
P/E Ratio (TTM)366.87148.21
P/S Ratio (TTM)4.075.37
P/B Ratio (MRQ)5.018.06
Free Cash Flow Yield (TTM)2.74%3.88%