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CRL vs. HALO: Charles River Laboratories vs. Halozyme Therapeutics Stock Comparison

How do Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but CRL is classified in Life Sciences Tools & Services while HALO is classified in Biotechnology.

Company profile comparison for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO)
Profile ItemCRLHALO
NameCharles River Laboratories International, Inc.Halozyme Therapeutics Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesBiotechnology
GICS Sub-IndustryLife Sciences Tools & ServicesBiotechnology
Market Capitalization16.17 billion USD11.81 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateJune 23, 2000March 16, 2004
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

CRL
HALO
GSPC
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO)
MetricCRLHALO
Total Return (1Y)110.83%50.94%
Total Return (3Y, Annualized)27.87%41.08%
Total Return (5Y, Annualized)-1.57%21.68%

Risk Profile

Drawdown History

CRL
HALO
GSPC
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO)
MetricCRLHALO
Volatility (1Y, Annualized)47.81%41.19%
Beta (5Y)1.330.96
Max Drawdown (5Y)-74.73%-49.06%
Avg. Volume (3M)1.05M2.29M

Risk-Adjusted Performance

Risk-Return Positioning

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CRL and HALO are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO)
MetricCRLHALO
Sharpe Ratio (1Y)2.231.13
Sortino Ratio (1Y)3.581.78

Profitability

ROE (TTM)

Halozyme Therapeutics (HALO) at 216.38% clears its industry range for ROE, a sharper capital-efficiency signal than Charles River Laboratories (CRL) at 1.27%, which is closer to a typical peer reading.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.27%

Max
109.18%
Q3
6.23%
CRL
1.27%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

216.38%

HALO
216.38%
Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Halozyme Therapeutics (HALO) at 26.93% converts revenue to bottom-line profit above its industry’s benchmark range, while Charles River Laboratories (CRL) at 1.01% keeps roughly the typical share for its industry.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.01%

Max
18.05%
Q3
4.78%
CRL
1.01%
Median
0.00%
Q1
-4.14%
Min
-17.05%

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.93%

HALO
26.93%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Charles River Laboratories (CRL) at 23.42% and Halozyme Therapeutics (HALO) at 59.84% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.42%

Max
83.12%
CRL
23.42%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

59.84%

Max
83.12%
HALO
59.84%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO)
MetricCRLHALO
ROE (TTM)1.27%216.38%
ROA (TTM)4.74%22.42%
Net Margin (TTM)1.01%26.93%
Operating Margin (TTM)23.42%59.84%
Gross Margin (TTM)35.10%77.74%

Growth

Revenue Growth

Halozyme Therapeutics (HALO) at 37.55% is around its peer norm for revenue growth, while Charles River Laboratories (CRL) at -0.85% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): A comparison of their Revenue Growth across different time periods.

EPS Growth

Halozyme Therapeutics (HALO) at -25.36% is around its peer norm for EPS growth, while Charles River Laboratories (CRL) at -1,555.00% falls below its industry range, a notably weak earnings reading.

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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO)
MetricCRLHALO
Revenue Growth (YoY)-0.85%37.55%
Revenue Growth (3Y CAGR)0.33%28.38%
EPS Growth (YoY)-1,555.00%-25.36%
EPS Growth (3Y CAGR)--21.14%

Financial Strength

Current Ratio (MRQ)

Halozyme Therapeutics (HALO) at 3.88 keeps current ratio within its industry’s typical mid-range, while Charles River Laboratories (CRL) at 1.41 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for CRL.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.41

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
CRL
1.41
Min
0.10

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.88

Max
25.13
Q3
12.13
Median
5.52
HALO
3.88
Q1
2.47
Min
0.10
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: Charles River Laboratories (CRL) carries debt-to-equity ratio of 0.87 against its industry range, while Halozyme Therapeutics (HALO) reports no figure this period.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87

Max
1.42
CRL
0.87
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
HALO
--
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): HALO does not report debt-to-equity ratio, so it has no value marker; CRL is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Financial Strength Metrics

Financial strength metrics for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO)
MetricCRLHALO
Current Ratio (MRQ)1.413.88
Debt / Equity (MRQ)0.87--
Net Debt / EBITDA2.921.90

Dividends

Dividend Yield (TTM)

Neither Charles River Laboratories (CRL) nor Halozyme Therapeutics (HALO) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

HALO
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Charles River Laboratories (CRL) nor Halozyme Therapeutics (HALO) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

HALO
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO)
MetricCRLHALO
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

Halozyme Therapeutics (HALO) at 25.91 is near its industry’s usual P/E ratio, while Charles River Laboratories (CRL) at 366.87 sits above its peer range — an unusually expensive price for CRL’s trailing earnings.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

366.87

CRL
366.87
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

25.91

Max
85.34
Q3
43.46
Median
26.69
HALO
25.91
Q1
13.30
Min
0.07
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Charles River Laboratories (CRL) at 4.07 and Halozyme Therapeutics (HALO) at 6.55 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.07

Max
58.18
Q3
25.77
Median
7.30
CRL
4.07
Q1
3.01
Min
0.01

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.55

Max
58.18
Q3
25.77
Median
7.30
HALO
6.55
Q1
3.01
Min
0.01
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Halozyme Therapeutics (HALO) reports a negative P/B ratio of -213.67, meaning negative book equity — the multiple itself is not meaningful for valuation. Meanwhile Charles River Laboratories (CRL) reports 5.01, ranking against industry peers normally.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.01

Max
13.53
Q3
6.54
CRL
5.01
Median
3.25
Q1
1.69
Min
-5.59

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

-213.67

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
HALO
-213.67
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Charles River Laboratories (CRL) vs. Halozyme Therapeutics (HALO): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Charles River Laboratories (CRL) and Halozyme Therapeutics (HALO)
MetricCRLHALO
P/E Ratio (TTM)366.8725.91
P/S Ratio (TTM)4.076.55
P/B Ratio (MRQ)5.01-213.67
Free Cash Flow Yield (TTM)2.74%3.48%