BMRN vs. PFE: BioMarin Pharmaceutical vs. Pfizer Stock Comparison

November 11, 2026

How do BioMarin Pharmaceutical (BMRN) and Pfizer (PFE) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

BioMarin Pharmaceutical (BMRN) and Pfizer (PFE) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but BMRN is classified in Biotechnology while PFE is classified in Pharmaceuticals.

Company profile comparison for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE)
Profile Item	BMRN	PFE
Name	BioMarin Pharmaceutical Inc.	Pfizer Inc.
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Pharmaceuticals, Biotechnology & Life Sciences	Pharmaceuticals, Biotechnology & Life Sciences
GICS Industry	Biotechnology	Pharmaceuticals
GICS Sub-Industry	Biotechnology	Pharmaceuticals
Market Capitalization	10.85 billion USD	167.52 billion USD
Currency	USD	USD
Exchange	Nasdaq	NYSE
Listing Date	July 26, 1999	June 1, 1972
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

BMRN

PFE

GSPC

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE)
Metric	BMRN	PFE
Total Return (1Y)	8.82%	28.65%
Total Return (3Y, Annualized)	-12.54%	6.41%
Total Return (5Y, Annualized)	-7.51%	-3.98%

Risk Profile

Drawdown History

BMRN

PFE

GSPC

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE)
Metric	BMRN	PFE
Volatility (1Y, Annualized)	35.50%	21.72%
Beta (5Y)	0.24	0.35
Max Drawdown (5Y)	-57.64%	-58.96%
Avg. Volume (3M)	2.28M	33.67M

Risk-Adjusted Performance

Risk-Return Positioning

BMRN and PFE are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE)
Metric	BMRN	PFE
Sharpe Ratio (1Y)	0.13	1.12
Sortino Ratio (1Y)	0.23	1.73

Profitability

ROE (TTM)

BioMarin Pharmaceutical (BMRN) reports a negative ROE of -0.31%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Pfizer (PFE) reports 4.47%, ranking against industry peers normally.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.31%

Max: 109.18%
Q3: 6.23%
BMRN: -0.31%
Median: -26.66%
Q1: -64.05%
Min: -167.77%

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.47%

Max: 109.18%
Q3: 6.23%
PFE: 4.47%
Median: -26.66%
Q1: -64.05%
Min: -167.77%

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

BioMarin Pharmaceutical (BMRN) reports a negative net margin of -0.52%, usually indicating a net loss over the period. Meanwhile Pfizer (PFE) reports 6.34%, ranking against industry peers normally.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.52%

Max: 18.05%
Q3: 4.78%
Median: 0.00%
BMRN: -0.52%
Q1: -4.14%
Min: -17.05%

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.34%

Max: 18.05%
PFE: 6.34%
Q3: 4.78%
Median: 0.00%
Q1: -4.14%
Min: -17.05%

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both BioMarin Pharmaceutical (BMRN) at 26.58% and Pfizer (PFE) at 33.38% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.58%

Max: 83.12%
BMRN: 26.58%
Q3: 14.77%
Median: 0.00%
Q1: -78.82%
Min: -207.40%

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

33.38%

Max: 83.12%
PFE: 33.38%
Q3: 14.77%
Median: 0.00%
Q1: -78.82%
Min: -207.40%

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE)
Metric	BMRN	PFE
ROE (TTM)	-0.31%	4.47%
ROA (TTM)	3.89%	5.59%
Net Margin (TTM)	-0.52%	6.34%
Operating Margin (TTM)	26.58%	33.38%
Gross Margin (TTM)	53.21%	74.90%

Growth

Revenue Growth

BioMarin Pharmaceutical (BMRN) at 12.87% is around its peer norm for revenue growth, while Pfizer (PFE) at -1.65% drops into the bottom quartile, signaling weaker demand or pricing momentum.

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): A comparison of their Revenue Growth across different time periods.

EPS Growth

Both BioMarin Pharmaceutical (BMRN) at -18.55% and Pfizer (PFE) at -3.55% land near their industries' usual EPS growth ranges, so bottom-line momentum looks broadly in line with peers on both sides.

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE)
Metric	BMRN	PFE
Revenue Growth (YoY)	12.87%	-1.65%
Revenue Growth (3Y CAGR)	15.40%	-14.80%
EPS Growth (YoY)	-18.55%	-3.55%
EPS Growth (3Y CAGR)	33.89%	-37.12%

Financial Strength

Current Ratio (MRQ)

Both BioMarin Pharmaceutical (BMRN) at 2.44 and Pfizer (PFE) at 1.42 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.44

Max: 25.13
Q3: 12.13
Median: 5.52
Q1: 2.47
BMRN: 2.44
Min: 0.10

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.42

Max: 25.13
Q3: 12.13
Median: 5.52
Q1: 2.47
PFE: 1.42
Min: 0.10

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both BioMarin Pharmaceutical (BMRN) at 0.67 and Pfizer (PFE) at 0.71 lean more heavily on debt funding than most peers, landing in the higher-leverage quartile of their industries.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.67

Max: 1.42
BMRN: 0.67
Q3: 0.65
Median: 0.15
Q1: 0.02
Min: 0.00

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.71

Max: 1.42
PFE: 0.71
Q3: 0.65
Median: 0.15
Q1: 0.02
Min: 0.00

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE)
Metric	BMRN	PFE
Current Ratio (MRQ)	2.44	1.42
Debt / Equity (MRQ)	0.67	0.71
Net Debt / EBITDA	4.04	1.97

Dividends

Dividend Yield (TTM)

BioMarin Pharmaceutical (BMRN) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Pfizer (PFE) reports a yield of 7.30%, ranking against industry peers normally.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BMRN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.30%

PFE: 7.30%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Pfizer (PFE) reports payout ratio above 100% at 245.71%, meaning dividends exceeded current-period earnings; BioMarin Pharmaceutical (BMRN) pays no dividend (payout 0.00%).

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BMRN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

245.71%

PFE: 245.71%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE)
Metric	BMRN	PFE
Dividend Yield (TTM)	0.00%	7.30%
Dividend Payout Ratio (TTM)	0.00%	245.71%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Pfizer (PFE) trades at 41.99 times trailing earnings, ranked against its peers, while BioMarin Pharmaceutical (BMRN) has no P/E ratio this period.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

Max: 85.34
Q3: 43.46
Median: 26.69
Q1: 13.30
Min: 0.07
BMRN: --

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

41.99

Max: 85.34
Q3: 43.46
PFE: 41.99
Median: 26.69
Q1: 13.30
Min: 0.07

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): BMRN does not report P/E ratio, so it has no value marker; PFE is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

Both BioMarin Pharmaceutical (BMRN) at 2.97 and Pfizer (PFE) at 2.63 fetch a relatively low price per dollar of sales, landing in the cheaper P/S ratio quartile of their industries.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.97

Max: 58.18
Q3: 25.77
Median: 7.30
Q1: 3.01
BMRN: 2.97
Min: 0.01

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.63

Max: 58.18
Q3: 25.77
Median: 7.30
Q1: 3.01
PFE: 2.63
Min: 0.01

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

On P/B ratio, both BioMarin Pharmaceutical (BMRN) at 1.73 and Pfizer (PFE) at 1.88 are valued close to their industries’ norm against book — neither stands out from peers.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.73

Max: 13.53
Q3: 6.54
Median: 3.25
BMRN: 1.73
Q1: 1.69
Min: -5.59

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.88

Max: 13.53
Q3: 6.54
Median: 3.25
PFE: 1.88
Q1: 1.69
Min: -5.59

BioMarin Pharmaceutical (BMRN) vs. Pfizer (PFE): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for BioMarin Pharmaceutical (BMRN) and Pfizer (PFE)
Metric	BMRN	PFE
P/E Ratio (TTM)	--	41.99
P/S Ratio (TTM)	2.97	2.63
P/B Ratio (MRQ)	1.73	1.88
Free Cash Flow Yield (TTM)	-0.15%	7.76%