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BMRN vs. EXEL: BioMarin Pharmaceutical vs. Exelixis Stock Comparison

How do BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL) are both classified in the Biotechnology sub-industry within the broader Biotechnology industry, placing them in the closest GICS peer bucket.

Company profile comparison for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL)
Profile ItemBMRNEXEL
NameBioMarin Pharmaceutical Inc.Exelixis Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyBiotechnology
GICS Sub-IndustryBiotechnologyBiotechnology
Market Capitalization10.85 billion USD16.98 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateJuly 26, 1999April 17, 2000
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

BMRN
EXEL
GSPC
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL)
MetricBMRNEXEL
Total Return (1Y)8.82%74.98%
Total Return (3Y, Annualized)-12.54%50.33%
Total Return (5Y, Annualized)-7.51%31.10%

Risk Profile

Drawdown History

BMRN
EXEL
GSPC
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL)
MetricBMRNEXEL
Volatility (1Y, Annualized)35.50%34.17%
Beta (5Y)0.240.41
Max Drawdown (5Y)-57.64%-35.41%
Avg. Volume (3M)2.28M2.33M

Risk-Adjusted Performance

Risk-Return Positioning

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BMRN and EXEL are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL)
MetricBMRNEXEL
Sharpe Ratio (1Y)0.132.07
Sortino Ratio (1Y)0.233.23

Profitability

ROE (TTM)

BioMarin Pharmaceutical (BMRN) reports a negative ROE of -0.31%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Exelixis (EXEL) reports 44.32%, ranking against industry peers normally.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.31%

Max
109.18%
Q3
6.23%
BMRN
-0.31%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

44.32%

Max
109.18%
EXEL
44.32%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

BioMarin Pharmaceutical (BMRN) reports a negative net margin of -0.52%, usually indicating a net loss over the period. Meanwhile Exelixis (EXEL) reports 35.45%, ranking against industry peers normally.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.52%

Max
18.05%
Q3
4.78%
Median
0.00%
BMRN
-0.52%
Q1
-4.14%
Min
-17.05%

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.45%

EXEL
35.45%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both BioMarin Pharmaceutical (BMRN) at 26.58% and Exelixis (EXEL) at 40.75% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.58%

Max
83.12%
BMRN
26.58%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

40.75%

Max
83.12%
EXEL
40.75%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL)
MetricBMRNEXEL
ROE (TTM)-0.31%44.32%
ROA (TTM)3.89%23.52%
Net Margin (TTM)-0.52%35.45%
Operating Margin (TTM)26.58%40.75%
Gross Margin (TTM)53.21%96.26%

Growth

Revenue Growth

Both BioMarin Pharmaceutical (BMRN) at 12.87% and Exelixis (EXEL) at 6.98% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): A comparison of their Revenue Growth across different time periods.

EPS Growth

Both BioMarin Pharmaceutical (BMRN) at -18.55% and Exelixis (EXEL) at 57.95% land near their industries' usual EPS growth ranges, so bottom-line momentum looks broadly in line with peers on both sides.

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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL)
MetricBMRNEXEL
Revenue Growth (YoY)12.87%6.98%
Revenue Growth (3Y CAGR)15.40%12.93%
EPS Growth (YoY)-18.55%57.95%
EPS Growth (3Y CAGR)33.89%70.59%

Financial Strength

Current Ratio (MRQ)

Exelixis (EXEL) at 3.21 keeps current ratio within its industry’s typical mid-range, while BioMarin Pharmaceutical (BMRN) at 2.44 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for BMRN.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.44

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
BMRN
2.44
Min
0.10

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.21

Max
25.13
Q3
12.13
Median
5.52
EXEL
3.21
Q1
2.47
Min
0.10
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Exelixis (EXEL) at 0.09 carries an industry-typical debt-to-equity mix, while BioMarin Pharmaceutical (BMRN) at 0.67 uses more debt funding than most peers.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.67

Max
1.42
BMRN
0.67
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.09

Max
1.42
Q3
0.65
Median
0.15
EXEL
0.09
Q1
0.02
Min
0.00
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL)
MetricBMRNEXEL
Current Ratio (MRQ)2.443.21
Debt / Equity (MRQ)0.670.09
Net Debt / EBITDA4.04-0.71

Dividends

Dividend Yield (TTM)

Neither BioMarin Pharmaceutical (BMRN) nor Exelixis (EXEL) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BMRN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

EXEL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither BioMarin Pharmaceutical (BMRN) nor Exelixis (EXEL) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BMRN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

EXEL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL)
MetricBMRNEXEL
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Exelixis (EXEL) trades at 20.83 times trailing earnings, ranked against its peers, while BioMarin Pharmaceutical (BMRN) has no P/E ratio this period.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
BMRN
--

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.83

Max
85.34
Q3
43.46
Median
26.69
EXEL
20.83
Q1
13.30
Min
0.07
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): BMRN does not report P/E ratio, so it has no value marker; EXEL is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

BioMarin Pharmaceutical (BMRN) at 2.97 sits in the cheaper P/S ratio quartile while Exelixis (EXEL) at 6.80 prices around its industry’s middle — BMRN costs less per dollar of sales, though read it alongside growth and margins.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.97

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
BMRN
2.97
Min
0.01

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.80

Max
58.18
Q3
25.77
Median
7.30
EXEL
6.80
Q1
3.01
Min
0.01
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

BioMarin Pharmaceutical (BMRN) at 1.73 is valued about in line with its industry on P/B ratio, while Exelixis (EXEL) at 9.28 carries an above-peer premium to book — EXEL is pricier on assets.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.73

Max
13.53
Q3
6.54
Median
3.25
BMRN
1.73
Q1
1.69
Min
-5.59

EXEL

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.28

Max
13.53
EXEL
9.28
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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BioMarin Pharmaceutical (BMRN) vs. Exelixis (EXEL): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for BioMarin Pharmaceutical (BMRN) and Exelixis (EXEL)
MetricBMRNEXEL
P/E Ratio (TTM)--20.83
P/S Ratio (TTM)2.976.80
P/B Ratio (MRQ)1.739.28
Free Cash Flow Yield (TTM)-0.15%4.47%