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BMRN vs. CRL: BioMarin Pharmaceutical vs. Charles River Laboratories Stock Comparison

How do BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but BMRN is classified in Biotechnology while CRL is classified in Life Sciences Tools & Services.

Company profile comparison for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL)
Profile ItemBMRNCRL
NameBioMarin Pharmaceutical Inc.Charles River Laboratories International, Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyLife Sciences Tools & Services
GICS Sub-IndustryBiotechnologyLife Sciences Tools & Services
Market Capitalization10.85 billion USD16.17 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateJuly 26, 1999June 23, 2000
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

BMRN
CRL
GSPC
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL)
MetricBMRNCRL
Total Return (1Y)8.82%110.83%
Total Return (3Y, Annualized)-12.54%27.87%
Total Return (5Y, Annualized)-7.51%-1.57%

Risk Profile

Drawdown History

BMRN
CRL
GSPC
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Charles River Laboratories (CRL) has an aggressive beta of 1.33, indicating higher sensitivity to broad-market moves, while BioMarin Pharmaceutical (BMRN) is defensive at 0.24 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL)
MetricBMRNCRL
Volatility (1Y, Annualized)35.50%47.81%
Beta (5Y)0.241.33
Max Drawdown (5Y)-57.64%-74.73%
Avg. Volume (3M)2.28M1.05M

Risk-Adjusted Performance

Risk-Return Positioning

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BMRN and CRL are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL)
MetricBMRNCRL
Sharpe Ratio (1Y)0.132.23
Sortino Ratio (1Y)0.233.58

Profitability

ROE (TTM)

BioMarin Pharmaceutical (BMRN) reports a negative ROE of -0.31%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Charles River Laboratories (CRL) reports 1.27%, ranking against industry peers normally.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.31%

Max
109.18%
Q3
6.23%
BMRN
-0.31%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.27%

Max
109.18%
Q3
6.23%
CRL
1.27%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

BioMarin Pharmaceutical (BMRN) reports a negative net margin of -0.52%, usually indicating a net loss over the period. Meanwhile Charles River Laboratories (CRL) reports 1.01%, ranking against industry peers normally.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.52%

Max
18.05%
Q3
4.78%
Median
0.00%
BMRN
-0.52%
Q1
-4.14%
Min
-17.05%

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.01%

Max
18.05%
Q3
4.78%
CRL
1.01%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both BioMarin Pharmaceutical (BMRN) at 26.58% and Charles River Laboratories (CRL) at 23.42% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.58%

Max
83.12%
BMRN
26.58%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.42%

Max
83.12%
CRL
23.42%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL)
MetricBMRNCRL
ROE (TTM)-0.31%1.27%
ROA (TTM)3.89%4.74%
Net Margin (TTM)-0.52%1.01%
Operating Margin (TTM)26.58%23.42%
Gross Margin (TTM)53.21%35.10%

Growth

Revenue Growth

BioMarin Pharmaceutical (BMRN) at 12.87% is around its peer norm for revenue growth, while Charles River Laboratories (CRL) at -0.85% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): A comparison of their Revenue Growth across different time periods.

EPS Growth

BioMarin Pharmaceutical (BMRN) at -18.55% is around its peer norm for EPS growth, while Charles River Laboratories (CRL) at -1,555.00% falls below its industry range, a notably weak earnings reading.

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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL)
MetricBMRNCRL
Revenue Growth (YoY)12.87%-0.85%
Revenue Growth (3Y CAGR)15.40%0.33%
EPS Growth (YoY)-18.55%-1,555.00%
EPS Growth (3Y CAGR)33.89%--

Financial Strength

Current Ratio (MRQ)

Both BioMarin Pharmaceutical (BMRN) at 2.44 and Charles River Laboratories (CRL) at 1.41 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.44

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
BMRN
2.44
Min
0.10

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.41

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
CRL
1.41
Min
0.10
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both BioMarin Pharmaceutical (BMRN) at 0.67 and Charles River Laboratories (CRL) at 0.87 lean more heavily on debt funding than most peers, landing in the higher-leverage quartile of their industries.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.67

Max
1.42
BMRN
0.67
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87

Max
1.42
CRL
0.87
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL)
MetricBMRNCRL
Current Ratio (MRQ)2.441.41
Debt / Equity (MRQ)0.670.87
Net Debt / EBITDA4.042.92

Dividends

Dividend Yield (TTM)

Neither BioMarin Pharmaceutical (BMRN) nor Charles River Laboratories (CRL) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BMRN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither BioMarin Pharmaceutical (BMRN) nor Charles River Laboratories (CRL) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BMRN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL)
MetricBMRNCRL
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Charles River Laboratories (CRL) trades at 366.87 times trailing earnings, ranked against its peers, while BioMarin Pharmaceutical (BMRN) has no P/E ratio this period.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
BMRN
--

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

366.87

CRL
366.87
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): BMRN does not report P/E ratio, so it has no value marker; CRL is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

BioMarin Pharmaceutical (BMRN) at 2.97 sits in the cheaper P/S ratio quartile while Charles River Laboratories (CRL) at 4.07 prices around its industry’s middle — BMRN costs less per dollar of sales, though read it alongside growth and margins.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.97

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
BMRN
2.97
Min
0.01

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.07

Max
58.18
Q3
25.77
Median
7.30
CRL
4.07
Q1
3.01
Min
0.01
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

On P/B ratio, both BioMarin Pharmaceutical (BMRN) at 1.73 and Charles River Laboratories (CRL) at 5.01 are valued close to their industries’ norm against book — neither stands out from peers.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.73

Max
13.53
Q3
6.54
Median
3.25
BMRN
1.73
Q1
1.69
Min
-5.59

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.01

Max
13.53
Q3
6.54
CRL
5.01
Median
3.25
Q1
1.69
Min
-5.59
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BioMarin Pharmaceutical (BMRN) vs. Charles River Laboratories (CRL): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for BioMarin Pharmaceutical (BMRN) and Charles River Laboratories (CRL)
MetricBMRNCRL
P/E Ratio (TTM)--366.87
P/S Ratio (TTM)2.974.07
P/B Ratio (MRQ)1.735.01
Free Cash Flow Yield (TTM)-0.15%2.74%