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BIO vs. TAK: Bio-Rad Laboratories vs. Takeda Pharmaceutical Stock Comparison

How do Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but BIO is classified in Life Sciences Tools & Services while TAK is classified in Pharmaceuticals.

Bio-Rad Laboratories (BIO) trades as ordinary local shares, while Takeda Pharmaceutical (TAK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK)
Profile ItemBIOTAK
NameBio-Rad Laboratories Inc.Takeda Pharmaceutical Co Ltd ADR
Country/RegionUnited StatesJapan
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesPharmaceuticals
GICS Sub-IndustryLife Sciences Tools & ServicesPharmaceuticals
Market Capitalization10.26 billion USD67.16 billion USD
CurrencyUSDUSD
ExchangeNYSENYSE
Listing DateFebruary 27, 1980January 5, 2010
Security TypeCommon StockADR

Price Performance

Cumulative Growth

BIO
TAK
GSPC
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK)
MetricBIOTAK
Total Return (1Y)28.31%54.54%
Total Return (3Y, Annualized)8.52%18.39%
Total Return (5Y, Annualized)-11.74%9.29%

Risk Profile

Drawdown History

BIO
TAK
GSPC
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Bio-Rad Laboratories (BIO) has a non-negative beta of 1.03.

Risk profile metrics for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK)
MetricBIOTAK
Volatility (1Y, Annualized)36.50%21.45%
Beta (5Y)1.03-0.01
Max Drawdown (5Y)-72.24%-24.83%
Avg. Volume (3M)250.78K2.61M

Risk-Adjusted Performance

Risk-Return Positioning

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BIO and TAK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK)
MetricBIOTAK
Sharpe Ratio (1Y)0.662.34
Sortino Ratio (1Y)0.983.88

Profitability

ROE (TTM)

Bio-Rad Laboratories (BIO) at 14.27% sits in the top ROE quartile, while Takeda Pharmaceutical (TAK) at 0.56% is closer to the peer norm — stronger capital efficiency for BIO.

BIO

Pharmaceuticals, Biotechnology & Life Sciences industry group

14.27%

Max
109.18%
BIO
14.27%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.56%

Max
109.18%
Q3
6.23%
TAK
0.56%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Bio-Rad Laboratories (BIO) at 39.45% converts revenue to bottom-line profit above its industry’s benchmark range, while Takeda Pharmaceutical (TAK) at 0.87% keeps roughly the typical share for its industry.

BIO

Pharmaceuticals, Biotechnology & Life Sciences industry group

39.45%

BIO
39.45%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87%

Max
18.05%
Q3
4.78%
TAK
0.87%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Takeda Pharmaceutical (TAK) at 24.55% operates in the top operating margin quartile, ahead of Bio-Rad Laboratories (BIO) at 11.82%, which runs around its industry’s norm.

BIO

Pharmaceuticals, Biotechnology & Life Sciences industry group

11.82%

Max
83.12%
Q3
14.77%
BIO
11.82%
Median
0.00%
Q1
-78.82%
Min
-207.40%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.55%

Max
83.12%
TAK
24.55%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK)
MetricBIOTAK
ROE (TTM)14.27%0.56%
ROA (TTM)1.50%3.27%
Net Margin (TTM)39.45%0.87%
Operating Margin (TTM)11.82%24.55%
Gross Margin (TTM)52.19%64.77%

Growth

Revenue Growth

Bio-Rad Laboratories (BIO) at 0.65% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Takeda Pharmaceutical (TAK) reports EPS growth of 77.96%, ranked against its industry; Bio-Rad Laboratories (BIO) has no EPS growth figure this period.

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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK)
MetricBIOTAK
Revenue Growth (YoY)0.65%-1.66%
Revenue Growth (3Y CAGR)-2.68%3.81%
EPS Growth (YoY)--77.96%
EPS Growth (3Y CAGR)---16.01%

Financial Strength

Current Ratio (MRQ)

Bio-Rad Laboratories (BIO) at 3.18 keeps current ratio within its industry’s typical mid-range, while Takeda Pharmaceutical (TAK) at 1.15 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for TAK.

BIO

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.18

Max
25.13
Q3
12.13
Median
5.52
BIO
3.18
Q1
2.47
Min
0.10

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.15

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TAK
1.15
Min
0.10
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Bio-Rad Laboratories (BIO) at 0.18 carries an industry-typical debt-to-equity mix, while Takeda Pharmaceutical (TAK) at 0.72 uses more debt funding than most peers.

BIO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.18

Max
1.42
Q3
0.65
BIO
0.18
Median
0.15
Q1
0.02
Min
0.00

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.72

Max
1.42
TAK
0.72
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK)
MetricBIOTAK
Current Ratio (MRQ)3.181.15
Debt / Equity (MRQ)0.180.72
Net Debt / EBITDA-0.733.61

Dividends

Dividend Yield (TTM)

Bio-Rad Laboratories (BIO) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Takeda Pharmaceutical (TAK) reports a yield of 953.28%, ranking against industry peers normally.

BIO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BIO
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

953.28%

TAK
953.28%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings; Bio-Rad Laboratories (BIO) pays no dividend (payout 0.00%).

BIO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BIO
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

426.53%

TAK
426.53%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK)
MetricBIOTAK
Dividend Yield (TTM)0.00%953.28%
Dividend Payout Ratio (TTM)0.00%426.53%

Valuation

P/E Ratio (TTM)

Bio-Rad Laboratories (BIO) at 10.14 sits in the cheaper P/E ratio quartile, while Takeda Pharmaceutical (TAK) at 300.29 trades above its peer range — a wide earnings-valuation gap relative to industry peers.

BIO

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.14

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
BIO
10.14
Min
0.07

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

300.29

TAK
300.29
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

Takeda Pharmaceutical (TAK) at 0.01 sits in the cheaper P/S ratio quartile while Bio-Rad Laboratories (BIO) at 3.96 prices around its industry’s middle — TAK costs less per dollar of sales, though read it alongside growth and margins.

BIO

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.96

Max
58.18
Q3
25.77
Median
7.30
BIO
3.96
Q1
3.01
Min
0.01

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
TAK
0.01
Min
0.01
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Relative to net asset value, both Bio-Rad Laboratories (BIO) at 1.35 and Takeda Pharmaceutical (TAK) at 1.43 look inexpensive, sitting in the lower P/B ratio quartile of their industries.

BIO

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.35

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
BIO
1.35
Min
-5.59

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.43

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
TAK
1.43
Min
-5.59
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Bio-Rad Laboratories (BIO) vs. Takeda Pharmaceutical (TAK): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Bio-Rad Laboratories (BIO) and Takeda Pharmaceutical (TAK)
MetricBIOTAK
P/E Ratio (TTM)10.14300.29
P/S Ratio (TTM)3.960.01
P/B Ratio (MRQ)1.351.43
Free Cash Flow Yield (TTM)2.65%1,014.61%