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AZN vs. RVMD: AstraZeneca vs. Revolution Medicines Stock Comparison

How do AstraZeneca (AZN) and Revolution Medicines (RVMD) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

AstraZeneca (AZN) and Revolution Medicines (RVMD) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but AZN is classified in Pharmaceuticals while RVMD is classified in Biotechnology.

AstraZeneca (AZN) has more than two decades of public-market history since May 12, 1993, whereas Revolution Medicines (RVMD) listed on February 13, 2020 and has a much shorter record to draw on.

Revolution Medicines (RVMD) trades as ordinary local shares, while AstraZeneca (AZN) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for AstraZeneca (AZN) and Revolution Medicines (RVMD)
Profile ItemAZNRVMD
NameAstraZeneca PLC American Depositary SharesRevolution Medicines, Inc.
Country/RegionUnited KingdomUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsBiotechnology
GICS Sub-IndustryPharmaceuticalsBiotechnology
Market Capitalization289.14 billion USD41.59 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateMay 12, 1993February 13, 2020
Security TypeADRCommon Stock

Price Performance

Cumulative Growth

AZN
RVMD
GSPC
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for AstraZeneca (AZN) and Revolution Medicines (RVMD). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for AstraZeneca (AZN) and Revolution Medicines (RVMD). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for AstraZeneca (AZN) and Revolution Medicines (RVMD)
MetricAZNRVMD
Total Return (1Y)12.64%224.80%
Total Return (3Y, Annualized)15.75%114.71%
Total Return (5Y, Annualized)10.63%43.47%

Risk Profile

Drawdown History

AZN
RVMD
GSPC
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for AstraZeneca (AZN) and Revolution Medicines (RVMD). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Revolution Medicines (RVMD) has an aggressive beta of 1.42, indicating higher sensitivity to broad-market moves, while AstraZeneca (AZN) is defensive at 0.22 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for AstraZeneca (AZN) and Revolution Medicines (RVMD)
MetricAZNRVMD
Volatility (1Y, Annualized)28.21%68.29%
Beta (5Y)0.221.42
Max Drawdown (5Y)-27.87%-55.71%
Avg. Volume (3M)3.14M2.06M

Risk-Adjusted Performance

Risk-Return Positioning

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AZN and RVMD are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for AstraZeneca (AZN) and Revolution Medicines (RVMD)
MetricAZNRVMD
Sharpe Ratio (1Y)0.303.23
Sortino Ratio (1Y)0.446.92

Profitability

ROE (TTM)

Revolution Medicines (RVMD) reports a negative ROE of -93.56%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile AstraZeneca (AZN) reports 22.57%, ranking against industry peers normally.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

22.57%

Max
109.18%
AZN
22.57%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

-93.56%

Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
RVMD
-93.56%
Min
-167.77%
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

AstraZeneca (AZN) at 17.68% retains a top-quartile share of revenue as profit, ahead of Revolution Medicines (RVMD) at 0.00%, which keeps about the industry-typical share.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.68%

Max
18.05%
AZN
17.68%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

Max
18.05%
Q3
4.78%
RVMD
0.00%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Revolution Medicines (RVMD) reports a negative operating margin of -188.88%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile AstraZeneca (AZN) reports 29.57%, ranking against industry peers normally.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

29.57%

Max
83.12%
AZN
29.57%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

-188.88%

Max
83.12%
Q3
14.77%
Median
0.00%
Q1
-78.82%
RVMD
-188.88%
Min
-207.40%
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for AstraZeneca (AZN) and Revolution Medicines (RVMD)
MetricAZNRVMD
ROE (TTM)22.57%-93.56%
ROA (TTM)8.59%-32.13%
Net Margin (TTM)17.68%0.00%
Operating Margin (TTM)29.57%-188.88%
Gross Margin (TTM)81.78%0.00%

Growth

Revenue Growth

Only one side can be read here: AstraZeneca (AZN) reports revenue growth of 8.63%, ranked against its industry; Revolution Medicines (RVMD) has no revenue growth figure this period.

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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: AstraZeneca (AZN) reports EPS growth of 45.33%, ranked against its industry; Revolution Medicines (RVMD) has no EPS growth figure this period.

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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for AstraZeneca (AZN) and Revolution Medicines (RVMD)
MetricAZNRVMD
Revenue Growth (YoY)8.63%--
Revenue Growth (3Y CAGR)9.82%--
EPS Growth (YoY)45.33%--
EPS Growth (3Y CAGR)45.80%--

Financial Strength

Current Ratio (MRQ)

Revolution Medicines (RVMD) at 8.36 keeps current ratio within its industry’s typical mid-range, while AstraZeneca (AZN) at 1.01 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for AZN.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.01

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
AZN
1.01
Min
0.10

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.36

Max
25.13
Q3
12.13
RVMD
8.36
Median
5.52
Q1
2.47
Min
0.10
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Revolution Medicines (RVMD) at 0.50 carries an industry-typical debt-to-equity mix, while AstraZeneca (AZN) at 0.66 uses more debt funding than most peers.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.66

Max
1.42
AZN
0.66
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.50

Max
1.42
Q3
0.65
RVMD
0.50
Median
0.15
Q1
0.02
Min
0.00
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for AstraZeneca (AZN) and Revolution Medicines (RVMD)
MetricAZNRVMD
Current Ratio (MRQ)1.018.36
Debt / Equity (MRQ)0.660.50
Net Debt / EBITDA1.23--

Dividends

Dividend Yield (TTM)

Revolution Medicines (RVMD) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile AstraZeneca (AZN) reports a yield of 1.73%, ranking against industry peers normally.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.73%

AZN
1.73%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RVMD
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Revolution Medicines (RVMD) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile AstraZeneca (AZN) reports a payout of 45.38%, ranking against industry peers normally.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

45.38%

AZN
45.38%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RVMD
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for AstraZeneca (AZN) and Revolution Medicines (RVMD)
MetricAZNRVMD
Dividend Yield (TTM)1.73%0.00%
Dividend Payout Ratio (TTM)45.38%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: AstraZeneca (AZN) trades at 26.37 times trailing earnings, ranked against its peers, while Revolution Medicines (RVMD) has no P/E ratio this period.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.37

Max
85.34
Q3
43.46
Median
26.69
AZN
26.37
Q1
13.30
Min
0.07

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
RVMD
--
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): RVMD does not report P/E ratio, so it has no value marker; AZN is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

AstraZeneca (AZN) at 4.63 prices around its industry’s typical P/S ratio, while Revolution Medicines (RVMD) at 210.51 clears its benchmark range — RVMD looks notably rich on sales.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.63

Max
58.18
Q3
25.77
Median
7.30
AZN
4.63
Q1
3.01
Min
0.01

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

210.51

RVMD
210.51
Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
Min
0.01
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

AstraZeneca (AZN) at 5.59 sits near its industry’s typical P/B ratio, while Revolution Medicines (RVMD) at 17.31 prices above its benchmark range — RVMD looks rich relative to book.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.59

Max
13.53
Q3
6.54
AZN
5.59
Median
3.25
Q1
1.69
Min
-5.59

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.31

RVMD
17.31
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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AstraZeneca (AZN) vs. Revolution Medicines (RVMD): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for AstraZeneca (AZN) and Revolution Medicines (RVMD)
MetricAZNRVMD
P/E Ratio (TTM)26.37--
P/S Ratio (TTM)4.63210.51
P/B Ratio (MRQ)5.5917.31
Free Cash Flow Yield (TTM)1.95%-2.13%