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ASND vs. TMO: Ascendis Pharma vs. Thermo Fisher Scientific Stock Comparison

How do Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ASND is classified in Biotechnology while TMO is classified in Life Sciences Tools & Services.

Company profile comparison for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO)
Profile ItemASNDTMO
NameAscendis Pharma A/SThermo Fisher Scientific Inc.
Country/RegionDenmarkUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyLife Sciences Tools & Services
GICS Sub-IndustryBiotechnologyLife Sciences Tools & Services
Market Capitalization16.90 billion USD257.42 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateJanuary 28, 2015March 17, 1980
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

ASND
TMO
GSPC
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO)
MetricASNDTMO
Total Return (1Y)29.46%24.62%
Total Return (3Y, Annualized)40.62%17.34%
Total Return (5Y, Annualized)10.03%3.11%

Risk Profile

Drawdown History

ASND
TMO
GSPC
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO)
MetricASNDTMO
Volatility (1Y, Annualized)38.62%29.96%
Beta (5Y)0.380.83
Max Drawdown (5Y)-55.93%-40.95%
Avg. Volume (3M)698.39K2.10M

Risk-Adjusted Performance

Risk-Return Positioning

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ASND and TMO are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO)
MetricASNDTMO
Sharpe Ratio (1Y)0.650.68
Sortino Ratio (1Y)0.991.02

Profitability

ROE (TTM)

Both companies show strong equity returns, but Ascendis Pharma (ASND) at 118.78% is the standout with ROE above its industry range; Thermo Fisher Scientific (TMO) at 13.38% also sits in the top quartile.

ASND

Pharmaceuticals, Biotechnology & Life Sciences industry group

118.78%

ASND
118.78%
Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.38%

Max
109.18%
TMO
13.38%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Ascendis Pharma (ASND) at 70.85% keeps the most of each sales dollar — above its industry’s net margin range — and Thermo Fisher Scientific (TMO) at 14.94% also retains a top-quartile share.

ASND

Pharmaceuticals, Biotechnology & Life Sciences industry group

70.85%

ASND
70.85%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

14.94%

Max
18.05%
TMO
14.94%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Ascendis Pharma (ASND) at 64.98% and Thermo Fisher Scientific (TMO) at 20.19% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

ASND

Pharmaceuticals, Biotechnology & Life Sciences industry group

64.98%

Max
83.12%
ASND
64.98%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.19%

Max
83.12%
TMO
20.19%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO)
MetricASNDTMO
ROE (TTM)118.78%13.38%
ROA (TTM)9.58%5.19%
Net Margin (TTM)70.85%14.94%
Operating Margin (TTM)64.98%20.19%
Gross Margin (TTM)91.30%41.26%

Growth

Revenue Growth

Ascendis Pharma (ASND) at 98.03% sits in the top revenue growth quartile, while Thermo Fisher Scientific (TMO) at 3.91% is closer to the peer norm — faster top-line expansion for ASND.

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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Thermo Fisher Scientific (TMO) reports EPS growth of 7.32%, ranked against its industry; Ascendis Pharma (ASND) has no EPS growth figure this period.

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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO)
MetricASNDTMO
Revenue Growth (YoY)98.03%3.91%
Revenue Growth (3Y CAGR)141.43%-0.27%
EPS Growth (YoY)--7.32%
EPS Growth (3Y CAGR)--0.21%

Financial Strength

Current Ratio (MRQ)

Ascendis Pharma (ASND) at 2.99 keeps current ratio within its industry’s typical mid-range, while Thermo Fisher Scientific (TMO) at 1.81 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for TMO.

ASND

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.99

Max
25.13
Q3
12.13
Median
5.52
ASND
2.99
Q1
2.47
Min
0.10

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.81

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TMO
1.81
Min
0.10
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Ascendis Pharma (ASND) at 0.31 carries an industry-typical debt-to-equity mix, while Thermo Fisher Scientific (TMO) at 0.75 uses more debt funding than most peers.

ASND

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.31

Max
1.42
Q3
0.65
ASND
0.31
Median
0.15
Q1
0.02
Min
0.00

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.75

Max
1.42
TMO
0.75
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO)
MetricASNDTMO
Current Ratio (MRQ)2.991.81
Debt / Equity (MRQ)0.310.75
Net Debt / EBITDA-1.372.91

Dividends

Dividend Yield (TTM)

Ascendis Pharma (ASND) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Thermo Fisher Scientific (TMO) reports a yield of 0.27%, ranking against industry peers normally.

ASND

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ASND
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.27%

TMO
0.27%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Ascendis Pharma (ASND) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Thermo Fisher Scientific (TMO) reports a payout of 9.70%, ranking against industry peers normally.

ASND

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ASND
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.70%

TMO
9.70%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO)
MetricASNDTMO
Dividend Yield (TTM)0.00%0.27%
Dividend Payout Ratio (TTM)0.00%9.70%

Valuation

P/E Ratio (TTM)

Both Ascendis Pharma (ASND) at 19.68 and Thermo Fisher Scientific (TMO) at 36.64 land around their industries’ usual P/E ratio levels — neither is getting a clear earnings-multiple discount or premium versus peers.

ASND

Pharmaceuticals, Biotechnology & Life Sciences industry group

19.68

Max
85.34
Q3
43.46
Median
26.69
ASND
19.68
Q1
13.30
Min
0.07

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

36.64

Max
85.34
Q3
43.46
TMO
36.64
Median
26.69
Q1
13.30
Min
0.07
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Ascendis Pharma (ASND) at 16.14 and Thermo Fisher Scientific (TMO) at 5.44 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

ASND

Pharmaceuticals, Biotechnology & Life Sciences industry group

16.14

Max
58.18
Q3
25.77
ASND
16.14
Median
7.30
Q1
3.01
Min
0.01

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.44

Max
58.18
Q3
25.77
Median
7.30
TMO
5.44
Q1
3.01
Min
0.01
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Thermo Fisher Scientific (TMO) at 4.70 is valued about in line with its industry on P/B ratio, while Ascendis Pharma (ASND) at 10.45 carries an above-peer premium to book — ASND is pricier on assets.

ASND

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.45

Max
13.53
ASND
10.45
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.70

Max
13.53
Q3
6.54
TMO
4.70
Median
3.25
Q1
1.69
Min
-5.59
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Ascendis Pharma (ASND) vs. Thermo Fisher Scientific (TMO): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Ascendis Pharma (ASND) and Thermo Fisher Scientific (TMO)
MetricASNDTMO
P/E Ratio (TTM)19.6836.64
P/S Ratio (TTM)16.145.44
P/B Ratio (MRQ)10.454.70
Free Cash Flow Yield (TTM)0.08%2.50%