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ARGX vs. MRK: argenx vs. Merck Stock Comparison

How do argenx (ARGX) and Merck (MRK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

argenx (ARGX) and Merck (MRK) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ARGX is classified in Biotechnology while MRK is classified in Pharmaceuticals.

Merck (MRK) trades as ordinary local shares, while argenx (ARGX) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for argenx (ARGX) and Merck (MRK)
Profile ItemARGXMRK
Nameargenx SE American Depositary ReceiptMerck & Co., Inc.
Country/RegionNetherlandsUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization58.31 billion USD361.73 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateMay 18, 2017January 2, 1962
Security TypeADRCommon Stock

Price Performance

Cumulative Growth

ARGX
MRK
GSPC
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argenx (ARGX) vs. Merck (MRK), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for argenx (ARGX) and Merck (MRK). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for argenx (ARGX) and Merck (MRK). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for argenx (ARGX) and Merck (MRK)
MetricARGXMRK
Total Return (1Y)11.91%76.14%
Total Return (3Y, Annualized)25.68%16.48%
Total Return (5Y, Annualized)24.22%15.77%

Risk Profile

Drawdown History

ARGX
MRK
GSPC
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argenx (ARGX) vs. Merck (MRK), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for argenx (ARGX) and Merck (MRK). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Merck (MRK) is heavily traded at around 10.24M shares per day, whereas argenx (ARGX) sees a more moderate 359.84K — larger orders in the latter may require more patience and tighter control over order sizing.

Risk profile metrics for argenx (ARGX) and Merck (MRK)
MetricARGXMRK
Volatility (1Y, Annualized)37.87%30.24%
Beta (5Y)0.450.11
Max Drawdown (5Y)-38.20%-43.44%
Avg. Volume (3M)359.84K10.24M

Risk-Adjusted Performance

Risk-Return Positioning

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ARGX and MRK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for argenx (ARGX) and Merck (MRK)
MetricARGXMRK
Sharpe Ratio (1Y)0.202.38
Sortino Ratio (1Y)0.314.33

Profitability

ROE (TTM)

Capital efficiency shows on one side only: Merck (MRK) earns 5.06% on shareholders’ equity, ranked against its industry; argenx (ARGX) has no ROE this period.

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
ARGX
--

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.06%

Max
109.18%
Q3
6.23%
MRK
5.06%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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argenx (ARGX) vs. Merck (MRK): ARGX does not report ROE, so it has no value marker; MRK is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Net Margin (TTM)

argenx (ARGX) at 31.73% converts revenue to bottom-line profit above its industry’s benchmark range, while Merck (MRK) at 3.64% keeps roughly the typical share for its industry.

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

31.73%

ARGX
31.73%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.64%

Max
18.05%
Q3
4.78%
MRK
3.64%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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argenx (ARGX) vs. Merck (MRK): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both argenx (ARGX) at 36.27% and Merck (MRK) at 35.22% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

36.27%

Max
83.12%
ARGX
36.27%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.22%

Max
83.12%
MRK
35.22%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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argenx (ARGX) vs. Merck (MRK): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for argenx (ARGX) and Merck (MRK)
MetricARGXMRK
ROE (TTM)--5.06%
ROA (TTM)--11.29%
Net Margin (TTM)31.73%3.64%
Operating Margin (TTM)36.27%35.22%
Gross Margin (TTM)59.84%75.20%

Growth

Revenue Growth

argenx (ARGX) at 89.64% sits in the top revenue growth quartile, while Merck (MRK) at 1.31% is closer to the peer norm — faster top-line expansion for ARGX.

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argenx (ARGX) vs. Merck (MRK): A comparison of their Revenue Growth across different time periods.

EPS Growth

Both argenx (ARGX) at 53.13% and Merck (MRK) at 8.01% land near their industries' usual EPS growth ranges, so bottom-line momentum looks broadly in line with peers on both sides.

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argenx (ARGX) vs. Merck (MRK): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for argenx (ARGX) and Merck (MRK)
MetricARGXMRK
Revenue Growth (YoY)89.64%1.31%
Revenue Growth (3Y CAGR)116.25%3.12%
EPS Growth (YoY)53.13%8.01%
EPS Growth (3Y CAGR)--8.43%

Financial Strength

Current Ratio (MRQ)

Short-term liquidity can only be read on one side of this pairing: Merck (MRK) shows current ratio of 1.35 against its industry benchmark, while argenx (ARGX) has no reading this period.

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
Min
0.10
ARGX
--

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.35

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
MRK
1.35
Min
0.10
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argenx (ARGX) vs. Merck (MRK): ARGX does not report current ratio, so it has no value marker; MRK is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Debt / Equity (MRQ)

argenx (ARGX) at 0.01 keeps leverage in the lower quartile, while Merck (MRK) at 1.20 sits in the higher-leverage quartile.

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.01

Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
ARGX
0.01
Min
0.00

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.20

Max
1.42
MRK
1.20
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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argenx (ARGX) vs. Merck (MRK): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for argenx (ARGX) and Merck (MRK)
MetricARGXMRK
Current Ratio (MRQ)--1.35
Debt / Equity (MRQ)0.011.20
Net Debt / EBITDA-2.701.50

Dividends

Dividend Yield (TTM)

argenx (ARGX) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Merck (MRK) reports a yield of 2.29%, ranking against industry peers normally.

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ARGX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.29%

MRK
2.29%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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argenx (ARGX) vs. Merck (MRK): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Merck (MRK) reports payout ratio above 100% at 343.43%, meaning dividends exceeded current-period earnings; argenx (ARGX) pays no dividend (payout 0.00%).

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ARGX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

343.43%

MRK
343.43%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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argenx (ARGX) vs. Merck (MRK): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for argenx (ARGX) and Merck (MRK)
MetricARGXMRK
Dividend Yield (TTM)0.00%2.29%
Dividend Payout Ratio (TTM)0.00%343.43%

Valuation

P/E Ratio (TTM)

argenx (ARGX) at 32.12 is near its industry’s usual P/E ratio, while Merck (MRK) at 148.21 sits above its peer range — an unusually expensive price for MRK’s trailing earnings.

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.12

Max
85.34
Q3
43.46
ARGX
32.12
Median
26.69
Q1
13.30
Min
0.07

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

148.21

MRK
148.21
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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argenx (ARGX) vs. Merck (MRK): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both argenx (ARGX) at 9.86 and Merck (MRK) at 5.37 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.86

Max
58.18
Q3
25.77
ARGX
9.86
Median
7.30
Q1
3.01
Min
0.01

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.37

Max
58.18
Q3
25.77
Median
7.30
MRK
5.37
Q1
3.01
Min
0.01
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argenx (ARGX) vs. Merck (MRK): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Both look rich against book: Merck (MRK) at 8.06 sits in the upper P/B ratio quartile, and argenx (ARGX) at 172.23 prices even higher, above its industry range.

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

172.23

ARGX
172.23
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

MRK

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.06

Max
13.53
MRK
8.06
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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argenx (ARGX) vs. Merck (MRK): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for argenx (ARGX) and Merck (MRK)
MetricARGXMRK
P/E Ratio (TTM)32.12148.21
P/S Ratio (TTM)9.865.37
P/B Ratio (MRQ)172.238.06
Free Cash Flow Yield (TTM)--3.88%