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AMGN vs. NVO: Amgen vs. Novo Nordisk Stock Comparison

How do Amgen (AMGN) and Novo Nordisk (NVO) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Amgen (AMGN) and Novo Nordisk (NVO) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but AMGN is classified in Biotechnology while NVO is classified in Pharmaceuticals.

Amgen (AMGN) trades as ordinary local shares, while Novo Nordisk (NVO) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for Amgen (AMGN) and Novo Nordisk (NVO)
Profile ItemAMGNNVO
NameAmgen Inc. Common StockNovo Nordisk A/S Sponsored ADR
Country/RegionUnited StatesDenmark
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization249.05 billion USD177.74 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateJune 17, 1983April 30, 1981
Security TypeCommon StockADR

Price Performance

Cumulative Growth

AMGN
NVO
GSPC
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Amgen (AMGN) vs. Novo Nordisk (NVO), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Amgen (AMGN) and Novo Nordisk (NVO). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Amgen (AMGN) and Novo Nordisk (NVO). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Amgen (AMGN) and Novo Nordisk (NVO)
MetricAMGNNVO
Total Return (1Y)48.82%-5.29%
Total Return (3Y, Annualized)24.31%-23.41%
Total Return (5Y, Annualized)20.67%-4.13%

Risk Profile

Drawdown History

AMGN
NVO
GSPC
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Amgen (AMGN) vs. Novo Nordisk (NVO), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Amgen (AMGN) and Novo Nordisk (NVO). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Amgen (AMGN) and Novo Nordisk (NVO)
MetricAMGNNVO
Volatility (1Y, Annualized)29.12%45.98%
Beta (5Y)0.430.67
Max Drawdown (5Y)-24.86%-74.70%
Avg. Volume (3M)2.76M12.11M

Risk-Adjusted Performance

Risk-Return Positioning

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AMGN and NVO are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Amgen (AMGN) and Novo Nordisk (NVO)
MetricAMGNNVO
Sharpe Ratio (1Y)1.53-0.21
Sortino Ratio (1Y)2.36-0.28

Profitability

ROE (TTM)

Both Amgen (AMGN) at 78.35% and Novo Nordisk (NVO) at 58.38% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

78.35%

Max
109.18%
AMGN
78.35%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

58.38%

Max
109.18%
NVO
58.38%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Both Amgen (AMGN) at 24.14% and Novo Nordisk (NVO) at 33.92% keep an unusually large share of revenue as bottom-line profit — each net margin clears its industry’s benchmark range.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.14%

AMGN
24.14%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

33.92%

NVO
33.92%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Amgen (AMGN) at 35.79% and Novo Nordisk (NVO) at 40.05% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.79%

Max
83.12%
AMGN
35.79%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

40.05%

Max
83.12%
NVO
40.05%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Amgen (AMGN) and Novo Nordisk (NVO)
MetricAMGNNVO
ROE (TTM)78.35%58.38%
ROA (TTM)8.91%19.05%
Net Margin (TTM)24.14%33.92%
Operating Margin (TTM)35.79%40.05%
Gross Margin (TTM)72.47%83.33%

Growth

Revenue Growth

Both Amgen (AMGN) at 9.95% and Novo Nordisk (NVO) at 6.43% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their Revenue Growth across different time periods.

EPS Growth

Amgen (AMGN) at 88.23% sits in the top EPS growth quartile, while Novo Nordisk (NVO) at 1.77% is closer to the peer norm — faster per-share earnings growth for AMGN.

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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Amgen (AMGN) and Novo Nordisk (NVO)
MetricAMGNNVO
Revenue Growth (YoY)9.95%6.43%
Revenue Growth (3Y CAGR)11.77%20.43%
EPS Growth (YoY)88.23%1.77%
EPS Growth (3Y CAGR)5.52%23.52%

Financial Strength

Current Ratio (MRQ)

Both Amgen (AMGN) at 1.48 and Novo Nordisk (NVO) at 0.85 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.48

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
AMGN
1.48
Min
0.10

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.85

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
NVO
0.85
Min
0.10
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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Novo Nordisk (NVO) at 0.62 is near its industry mid-range for debt-to-equity ratio, while Amgen (AMGN) at 3.76 sits above its benchmark range, pointing to a heavier debt load relative to equity.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.76

AMGN
3.76
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.62

Max
1.42
Q3
0.65
NVO
0.62
Median
0.15
Q1
0.02
Min
0.00
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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Amgen (AMGN) and Novo Nordisk (NVO)
MetricAMGNNVO
Current Ratio (MRQ)1.480.85
Debt / Equity (MRQ)3.760.62
Net Debt / EBITDA2.310.49

Dividends

Dividend Yield (TTM)

Both Amgen (AMGN) at 2.16% and Novo Nordisk (NVO) at 29.03% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.16%

AMGN
2.16%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

29.03%

NVO
29.03%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Both Amgen (AMGN) at 57.62% and Novo Nordisk (NVO) at 45.36% pay out more of their earnings than any of their industry peers — the thinnest cover in their groups, so dividend headroom deserves attention.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

57.62%

AMGN
57.62%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

45.36%

NVO
45.36%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Amgen (AMGN) and Novo Nordisk (NVO)
MetricAMGNNVO
Dividend Yield (TTM)2.16%29.03%
Dividend Payout Ratio (TTM)57.62%45.36%

Valuation

P/E Ratio (TTM)

Novo Nordisk (NVO) at 10.18 sits in the cheaper P/E ratio quartile, while Amgen (AMGN) at 26.69 is closer to its industry’s usual earnings multiple — a discount for NVO, though growth and earnings durability still matter.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.69

Max
85.34
Q3
43.46
AMGN
26.69
Median
26.69
Q1
13.30
Min
0.07

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.18

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
NVO
10.18
Min
0.07
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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

Novo Nordisk (NVO) at 0.53 sits in the cheaper P/S ratio quartile while Amgen (AMGN) at 6.40 prices around its industry’s middle — NVO costs less per dollar of sales, though read it alongside growth and margins.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.40

Max
58.18
Q3
25.77
Median
7.30
AMGN
6.40
Q1
3.01
Min
0.01

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.53

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
NVO
0.53
Min
0.01
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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Novo Nordisk (NVO) at 5.43 sits near its industry’s typical P/B ratio, while Amgen (AMGN) at 17.35 prices above its benchmark range — AMGN looks rich relative to book.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.35

AMGN
17.35
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.43

Max
13.53
Q3
6.54
NVO
5.43
Median
3.25
Q1
1.69
Min
-5.59
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Amgen (AMGN) vs. Novo Nordisk (NVO): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Amgen (AMGN) and Novo Nordisk (NVO)
MetricAMGNNVO
P/E Ratio (TTM)26.6910.18
P/S Ratio (TTM)6.400.53
P/B Ratio (MRQ)17.355.43
Free Cash Flow Yield (TTM)2.96%18.43%