Seek Returns

AMGN vs. CRL: Amgen vs. Charles River Laboratories Stock Comparison

How do Amgen (AMGN) and Charles River Laboratories (CRL) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Amgen (AMGN) and Charles River Laboratories (CRL) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but AMGN is classified in Biotechnology while CRL is classified in Life Sciences Tools & Services.

Company profile comparison for Amgen (AMGN) and Charles River Laboratories (CRL)
Profile ItemAMGNCRL
NameAmgen Inc. Common StockCharles River Laboratories International, Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyLife Sciences Tools & Services
GICS Sub-IndustryBiotechnologyLife Sciences Tools & Services
Market Capitalization249.05 billion USD16.17 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateJune 17, 1983June 23, 2000
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

AMGN
CRL
GSPC
Loading price history…
Amgen (AMGN) vs. Charles River Laboratories (CRL), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

Loading price history…
Trailing total returns for Amgen (AMGN) and Charles River Laboratories (CRL). Returns over one year are annualized.

Calendar-Year Returns

Loading price history…
Calendar-year total returns for Amgen (AMGN) and Charles River Laboratories (CRL). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Amgen (AMGN) and Charles River Laboratories (CRL)
MetricAMGNCRL
Total Return (1Y)48.82%110.83%
Total Return (3Y, Annualized)24.31%27.87%
Total Return (5Y, Annualized)20.67%-1.57%

Risk Profile

Drawdown History

AMGN
CRL
GSPC
Loading price history…
Amgen (AMGN) vs. Charles River Laboratories (CRL), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

Loading price history…
Distribution of monthly total returns for Amgen (AMGN) and Charles River Laboratories (CRL). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Charles River Laboratories (CRL) has an aggressive beta of 1.33, indicating higher sensitivity to broad-market moves, while Amgen (AMGN) is defensive at 0.43 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Amgen (AMGN) and Charles River Laboratories (CRL)
MetricAMGNCRL
Volatility (1Y, Annualized)29.12%47.81%
Beta (5Y)0.431.33
Max Drawdown (5Y)-24.86%-74.73%
Avg. Volume (3M)2.76M1.05M

Risk-Adjusted Performance

Risk-Return Positioning

Loading chart…
AMGN and CRL are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Amgen (AMGN) and Charles River Laboratories (CRL)
MetricAMGNCRL
Sharpe Ratio (1Y)1.532.23
Sortino Ratio (1Y)2.363.58

Profitability

ROE (TTM)

Amgen (AMGN) at 78.35% sits in the top ROE quartile, while Charles River Laboratories (CRL) at 1.27% is closer to the peer norm — stronger capital efficiency for AMGN.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

78.35%

Max
109.18%
AMGN
78.35%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.27%

Max
109.18%
Q3
6.23%
CRL
1.27%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Amgen (AMGN) at 24.14% converts revenue to bottom-line profit above its industry’s benchmark range, while Charles River Laboratories (CRL) at 1.01% keeps roughly the typical share for its industry.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.14%

AMGN
24.14%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.01%

Max
18.05%
Q3
4.78%
CRL
1.01%
Median
0.00%
Q1
-4.14%
Min
-17.05%
Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Amgen (AMGN) at 35.79% and Charles River Laboratories (CRL) at 23.42% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.79%

Max
83.12%
AMGN
35.79%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.42%

Max
83.12%
CRL
23.42%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Amgen (AMGN) and Charles River Laboratories (CRL)
MetricAMGNCRL
ROE (TTM)78.35%1.27%
ROA (TTM)8.91%4.74%
Net Margin (TTM)24.14%1.01%
Operating Margin (TTM)35.79%23.42%
Gross Margin (TTM)72.47%35.10%

Growth

Revenue Growth

Amgen (AMGN) at 9.95% is around its peer norm for revenue growth, while Charles River Laboratories (CRL) at -0.85% drops into the bottom quartile, signaling weaker demand or pricing momentum.

Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their Revenue Growth across different time periods.

EPS Growth

Amgen (AMGN) at 88.23% sits in the top EPS growth quartile, while Charles River Laboratories (CRL) at -1,555.00% falls below its industry range — a large difference in per-share earnings trajectories.

Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Amgen (AMGN) and Charles River Laboratories (CRL)
MetricAMGNCRL
Revenue Growth (YoY)9.95%-0.85%
Revenue Growth (3Y CAGR)11.77%0.33%
EPS Growth (YoY)88.23%-1,555.00%
EPS Growth (3Y CAGR)5.52%--

Financial Strength

Current Ratio (MRQ)

Both Amgen (AMGN) at 1.48 and Charles River Laboratories (CRL) at 1.41 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.48

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
AMGN
1.48
Min
0.10

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.41

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
CRL
1.41
Min
0.10
Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both balance sheets lean debt-heavy versus peers, but AMGN is more stretched: Charles River Laboratories (CRL) at 0.87 sits in the higher-leverage quartile and Amgen (AMGN) at 3.76 is above its industry benchmark range.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.76

AMGN
3.76
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87

Max
1.42
CRL
0.87
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Amgen (AMGN) and Charles River Laboratories (CRL)
MetricAMGNCRL
Current Ratio (MRQ)1.481.41
Debt / Equity (MRQ)3.760.87
Net Debt / EBITDA2.312.92

Dividends

Dividend Yield (TTM)

Charles River Laboratories (CRL) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Amgen (AMGN) reports a yield of 2.16%, ranking against industry peers normally.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.16%

AMGN
2.16%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Charles River Laboratories (CRL) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Amgen (AMGN) reports a payout of 57.62%, ranking against industry peers normally.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

57.62%

AMGN
57.62%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Amgen (AMGN) and Charles River Laboratories (CRL)
MetricAMGNCRL
Dividend Yield (TTM)2.16%0.00%
Dividend Payout Ratio (TTM)57.62%0.00%

Valuation

P/E Ratio (TTM)

Amgen (AMGN) at 26.69 is near its industry’s usual P/E ratio, while Charles River Laboratories (CRL) at 366.87 sits above its peer range — an unusually expensive price for CRL’s trailing earnings.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.69

Max
85.34
Q3
43.46
AMGN
26.69
Median
26.69
Q1
13.30
Min
0.07

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

366.87

CRL
366.87
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Amgen (AMGN) at 6.40 and Charles River Laboratories (CRL) at 4.07 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.40

Max
58.18
Q3
25.77
Median
7.30
AMGN
6.40
Q1
3.01
Min
0.01

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.07

Max
58.18
Q3
25.77
Median
7.30
CRL
4.07
Q1
3.01
Min
0.01
Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Charles River Laboratories (CRL) at 5.01 sits near its industry’s typical P/B ratio, while Amgen (AMGN) at 17.35 prices above its benchmark range — AMGN looks rich relative to book.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.35

AMGN
17.35
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.01

Max
13.53
Q3
6.54
CRL
5.01
Median
3.25
Q1
1.69
Min
-5.59
Loading chart…
Amgen (AMGN) vs. Charles River Laboratories (CRL): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Amgen (AMGN) and Charles River Laboratories (CRL)
MetricAMGNCRL
P/E Ratio (TTM)26.69366.87
P/S Ratio (TTM)6.404.07
P/B Ratio (MRQ)17.355.01
Free Cash Flow Yield (TTM)2.96%2.74%