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ALNY vs. IQV: Alnylam Pharmaceuticals vs. IQVIA Stock Comparison

How do Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ALNY is classified in Biotechnology while IQV is classified in Life Sciences Tools & Services.

Company profile comparison for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV)
Profile ItemALNYIQV
NameAlnylam Pharmaceuticals, Inc.IQVIA Holdings Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyLife Sciences Tools & Services
GICS Sub-IndustryBiotechnologyLife Sciences Tools & Services
Market Capitalization20.89 billion USD44.80 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateJune 1, 2004May 9, 2013
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

ALNY
IQV
GSPC
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV)
MetricALNYIQV
Total Return (1Y)-64.57%32.11%
Total Return (3Y, Annualized)-1.58%13.15%
Total Return (5Y, Annualized)-3.13%2.00%

Risk Profile

Drawdown History

ALNY
IQV
GSPC
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV)
MetricALNYIQV
Volatility (1Y, Annualized)54.08%40.77%
Beta (5Y)0.451.14
Max Drawdown (5Y)-68.25%-51.52%
Avg. Volume (3M)1.90M1.40M

Risk-Adjusted Performance

Risk-Return Positioning

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ALNY and IQV are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV)
MetricALNYIQV
Sharpe Ratio (1Y)-1.270.68
Sortino Ratio (1Y)-1.451.03

Profitability

ROE (TTM)

Both companies show strong equity returns, but Alnylam Pharmaceuticals (ALNY) at 138.07% is the standout with ROE above its industry range; IQVIA (IQV) at 21.39% also sits in the top quartile.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

138.07%

ALNY
138.07%
Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

21.39%

Max
109.18%
IQV
21.39%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Alnylam Pharmaceuticals (ALNY) at 52.85% keeps the most of each sales dollar — above its industry’s net margin range — and IQVIA (IQV) at 8.05% also retains a top-quartile share.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

52.85%

ALNY
52.85%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.05%

Max
18.05%
IQV
8.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Alnylam Pharmaceuticals (ALNY) at 23.72% operates in the top operating margin quartile, ahead of IQVIA (IQV) at 13.73%, which runs around its industry’s norm.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.72%

Max
83.12%
ALNY
23.72%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.73%

Max
83.12%
Q3
14.77%
IQV
13.73%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV)
MetricALNYIQV
ROE (TTM)138.07%21.39%
ROA (TTM)9.51%5.08%
Net Margin (TTM)52.85%8.05%
Operating Margin (TTM)23.72%13.73%
Gross Margin (TTM)77.28%33.07%

Growth

Revenue Growth

Alnylam Pharmaceuticals (ALNY) at 65.19% sits in the top revenue growth quartile, while IQVIA (IQV) at 5.87% is closer to the peer norm — faster top-line expansion for ALNY.

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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: IQVIA (IQV) reports EPS growth of 4.67%, ranked against its industry; Alnylam Pharmaceuticals (ALNY) has no EPS growth figure this period.

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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV)
MetricALNYIQV
Revenue Growth (YoY)65.19%5.87%
Revenue Growth (3Y CAGR)52.98%4.21%
EPS Growth (YoY)--4.67%
EPS Growth (3Y CAGR)--11.08%

Financial Strength

Current Ratio (MRQ)

Alnylam Pharmaceuticals (ALNY) at 2.48 keeps current ratio within its industry’s typical mid-range, while IQVIA (IQV) at 0.83 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for IQV.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.48

Max
25.13
Q3
12.13
Median
5.52
ALNY
2.48
Q1
2.47
Min
0.10

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.83

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
IQV
0.83
Min
0.10
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both balance sheets lean debt-heavy versus peers, but IQV is more stretched: Alnylam Pharmaceuticals (ALNY) at 0.83 sits in the higher-leverage quartile and IQVIA (IQV) at 2.40 is above its industry benchmark range.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.83

Max
1.42
ALNY
0.83
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.40

IQV
2.40
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV)
MetricALNYIQV
Current Ratio (MRQ)2.480.83
Debt / Equity (MRQ)0.832.40
Net Debt / EBITDA-0.574.46

Dividends

Dividend Yield (TTM)

Neither Alnylam Pharmaceuticals (ALNY) nor IQVIA (IQV) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ALNY
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

IQV
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Alnylam Pharmaceuticals (ALNY) nor IQVIA (IQV) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ALNY
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

IQV
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV)
MetricALNYIQV
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

Alnylam Pharmaceuticals (ALNY) at 7.88 sits in the cheaper P/E ratio quartile, while IQVIA (IQV) at 33.07 is closer to its industry’s usual earnings multiple — a discount for ALNY, though growth and earnings durability still matter.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.88

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
ALNY
7.88
Min
0.07

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

33.07

Max
85.34
Q3
43.46
IQV
33.07
Median
26.69
Q1
13.30
Min
0.07
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

IQVIA (IQV) at 2.59 sits in the cheaper P/S ratio quartile while Alnylam Pharmaceuticals (ALNY) at 4.17 prices around its industry’s middle — IQV costs less per dollar of sales, though read it alongside growth and margins.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.17

Max
58.18
Q3
25.77
Median
7.30
ALNY
4.17
Q1
3.01
Min
0.01

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.59

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
IQV
2.59
Min
0.01
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Alnylam Pharmaceuticals (ALNY) at 5.79 is valued about in line with its industry on P/B ratio, while IQVIA (IQV) at 6.73 carries an above-peer premium to book — IQV is pricier on assets.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.79

Max
13.53
Q3
6.54
ALNY
5.79
Median
3.25
Q1
1.69
Min
-5.59

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.73

Max
13.53
IQV
6.73
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Alnylam Pharmaceuticals (ALNY) vs. IQVIA (IQV): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Alnylam Pharmaceuticals (ALNY) and IQVIA (IQV)
MetricALNYIQV
P/E Ratio (TTM)7.8833.07
P/S Ratio (TTM)4.172.59
P/B Ratio (MRQ)5.796.73
Free Cash Flow Yield (TTM)1.57%4.72%