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TEM vs. UTHR: Tempus AI vs. United Therapeutics Stock Comparison

How do Tempus AI (TEM) and United Therapeutics (UTHR) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Tempus AI (TEM) and United Therapeutics (UTHR) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but TEM is classified in Life Sciences Tools & Services while UTHR is classified in Biotechnology.

United Therapeutics (UTHR) carries decades of public-market history since June 17, 1999, while Tempus AI (TEM) listed on June 14, 2024 — long-window comparisons have far more historical data on the UTHR side.

Company profile comparison for Tempus AI (TEM) and United Therapeutics (UTHR)
Profile ItemTEMUTHR
NameTempus AI Inc Class A Common StockUnited Therapeutics Corporation
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesBiotechnology
GICS Sub-IndustryLife Sciences Tools & ServicesBiotechnology
Market Capitalization13.87 billion USD23.94 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateJune 14, 2024June 17, 1999
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

TEM
UTHR
GSPC
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Tempus AI (TEM) vs. United Therapeutics (UTHR), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Tempus AI (TEM) and United Therapeutics (UTHR). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Tempus AI (TEM) and United Therapeutics (UTHR). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Tempus AI (TEM) and United Therapeutics (UTHR)
MetricTEMUTHR
Total Return (1Y)16.25%28.77%
Total Return (3Y, Annualized)--37.63%
Total Return (5Y, Annualized)--23.78%

Risk Profile

Drawdown History

TEM
UTHR
GSPC
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Tempus AI (TEM) vs. United Therapeutics (UTHR), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Tempus AI (TEM) and United Therapeutics (UTHR). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Tempus AI (TEM) has a highly aggressive beta of 3.34, indicating much higher sensitivity to broad-market moves, while United Therapeutics (UTHR) is defensive at 0.49 and tends to be less market-sensitive — a wide gap in beta profiles.

Risk profile metrics for Tempus AI (TEM) and United Therapeutics (UTHR)
MetricTEMUTHR
Volatility (1Y, Annualized)76.08%35.00%
Beta (5Y)3.340.49
Max Drawdown (5Y)-59.76%-33.00%
Avg. Volume (3M)7.20M694.55K

Risk-Adjusted Performance

Risk-Return Positioning

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TEM and UTHR are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Tempus AI (TEM) and United Therapeutics (UTHR)
MetricTEMUTHR
Sharpe Ratio (1Y)0.160.70
Sortino Ratio (1Y)0.261.29

Profitability

ROE (TTM)

Tempus AI (TEM) reports a negative ROE of -37.55%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile United Therapeutics (UTHR) reports 19.13%, ranking against industry peers normally.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-37.55%

Max
109.18%
Q3
6.23%
Median
-26.66%
TEM
-37.55%
Q1
-64.05%
Min
-167.77%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

19.13%

Max
109.18%
UTHR
19.13%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Tempus AI (TEM) vs. United Therapeutics (UTHR): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Tempus AI (TEM) reports a negative net margin of -12.54%, usually indicating a net loss over the period. Meanwhile United Therapeutics (UTHR) reports 38.61%, ranking against industry peers normally.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-12.54%

Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
TEM
-12.54%
Min
-17.05%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

38.61%

UTHR
38.61%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Tempus AI (TEM) vs. United Therapeutics (UTHR): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Tempus AI (TEM) reports a negative operating margin of -13.82%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile United Therapeutics (UTHR) reports 28.99%, ranking against industry peers normally.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-13.82%

Max
83.12%
Q3
14.77%
Median
0.00%
TEM
-13.82%
Q1
-78.82%
Min
-207.40%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.99%

Max
83.12%
UTHR
28.99%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Tempus AI (TEM) vs. United Therapeutics (UTHR): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Tempus AI (TEM) and United Therapeutics (UTHR)
MetricTEMUTHR
ROE (TTM)-37.55%19.13%
ROA (TTM)-7.36%10.91%
Net Margin (TTM)-12.54%38.61%
Operating Margin (TTM)-13.82%28.99%
Gross Margin (TTM)64.46%86.34%

Growth

Revenue Growth

Tempus AI (TEM) at 83.41% sits in the top revenue growth quartile, while United Therapeutics (UTHR) at 10.61% is closer to the peer norm — faster top-line expansion for TEM.

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Tempus AI (TEM) vs. United Therapeutics (UTHR): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: United Therapeutics (UTHR) reports EPS growth of 13.07%, ranked against its industry; Tempus AI (TEM) has no EPS growth figure this period.

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Tempus AI (TEM) vs. United Therapeutics (UTHR): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Tempus AI (TEM) and United Therapeutics (UTHR)
MetricTEMUTHR
Revenue Growth (YoY)83.41%10.61%
Revenue Growth (3Y CAGR)58.29%18.02%
EPS Growth (YoY)--13.07%
EPS Growth (3Y CAGR)--22.92%

Financial Strength

Current Ratio (MRQ)

Both Tempus AI (TEM) at 2.61 and United Therapeutics (UTHR) at 4.61 carry current ratio within their industries’ typical mid-ranges, suggesting balanced short-term liquidity relative to peers.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.61

Max
25.13
Q3
12.13
Median
5.52
TEM
2.61
Q1
2.47
Min
0.10

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.61

Max
25.13
Q3
12.13
Median
5.52
UTHR
4.61
Q1
2.47
Min
0.10
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Tempus AI (TEM) vs. United Therapeutics (UTHR): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: Tempus AI (TEM) carries debt-to-equity ratio of 2.86 against its industry range, while United Therapeutics (UTHR) reports no figure this period.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.86

TEM
2.86
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
UTHR
--
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Tempus AI (TEM) vs. United Therapeutics (UTHR): UTHR does not report debt-to-equity ratio, so it has no value marker; TEM is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Financial Strength Metrics

Financial strength metrics for Tempus AI (TEM) and United Therapeutics (UTHR)
MetricTEMUTHR
Current Ratio (MRQ)2.614.61
Debt / Equity (MRQ)2.86--
Net Debt / EBITDA---1.53

Dividends

Dividend Yield (TTM)

Neither Tempus AI (TEM) nor United Therapeutics (UTHR) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

TEM
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

UTHR
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Tempus AI (TEM) vs. United Therapeutics (UTHR): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Tempus AI (TEM) nor United Therapeutics (UTHR) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

TEM
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

UTHR
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Tempus AI (TEM) vs. United Therapeutics (UTHR): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Tempus AI (TEM) and United Therapeutics (UTHR)
MetricTEMUTHR
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: United Therapeutics (UTHR) trades at 21.22 times trailing earnings, ranked against its peers, while Tempus AI (TEM) has no P/E ratio this period.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
TEM
--

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

21.22

Max
85.34
Q3
43.46
Median
26.69
UTHR
21.22
Q1
13.30
Min
0.07
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Tempus AI (TEM) vs. United Therapeutics (UTHR): TEM does not report P/E ratio, so it has no value marker; UTHR is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

On P/S ratio, both Tempus AI (TEM) at 9.19 and United Therapeutics (UTHR) at 7.51 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.19

Max
58.18
Q3
25.77
TEM
9.19
Median
7.30
Q1
3.01
Min
0.01

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.51

Max
58.18
Q3
25.77
UTHR
7.51
Median
7.30
Q1
3.01
Min
0.01
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Tempus AI (TEM) vs. United Therapeutics (UTHR): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

United Therapeutics (UTHR) at 3.80 sits near its industry’s typical P/B ratio, while Tempus AI (TEM) at 27.66 prices above its benchmark range — TEM looks rich relative to book.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

27.66

TEM
27.66
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.80

Max
13.53
Q3
6.54
UTHR
3.80
Median
3.25
Q1
1.69
Min
-5.59
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Tempus AI (TEM) vs. United Therapeutics (UTHR): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Tempus AI (TEM) and United Therapeutics (UTHR)
MetricTEMUTHR
P/E Ratio (TTM)--21.22
P/S Ratio (TTM)9.197.51
P/B Ratio (MRQ)27.663.80
Free Cash Flow Yield (TTM)0.30%1.90%