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TAK vs. UTHR: Takeda Pharmaceutical vs. United Therapeutics Stock Comparison

How do Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but TAK is classified in Pharmaceuticals while UTHR is classified in Biotechnology.

United Therapeutics (UTHR) trades as ordinary local shares, while Takeda Pharmaceutical (TAK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR)
Profile ItemTAKUTHR
NameTakeda Pharmaceutical Co Ltd ADRUnited Therapeutics Corporation
Country/RegionJapanUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsBiotechnology
GICS Sub-IndustryPharmaceuticalsBiotechnology
Market Capitalization67.16 billion USD23.94 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateJanuary 5, 2010June 17, 1999
Security TypeADRCommon Stock

Price Performance

Cumulative Growth

TAK
UTHR
GSPC
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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR)
MetricTAKUTHR
Total Return (1Y)54.54%28.77%
Total Return (3Y, Annualized)18.39%37.63%
Total Return (5Y, Annualized)9.29%23.78%

Risk Profile

Drawdown History

TAK
UTHR
GSPC
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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. United Therapeutics (UTHR) has a non-negative beta of 0.49.

Risk profile metrics for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR)
MetricTAKUTHR
Volatility (1Y, Annualized)21.45%35.00%
Beta (5Y)-0.010.49
Max Drawdown (5Y)-24.83%-33.00%
Avg. Volume (3M)2.61M694.55K

Risk-Adjusted Performance

Risk-Return Positioning

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TAK and UTHR are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR)
MetricTAKUTHR
Sharpe Ratio (1Y)2.340.70
Sortino Ratio (1Y)3.881.29

Profitability

ROE (TTM)

United Therapeutics (UTHR) at 19.13% sits in the top ROE quartile, while Takeda Pharmaceutical (TAK) at 0.56% is closer to the peer norm — stronger capital efficiency for UTHR.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.56%

Max
109.18%
Q3
6.23%
TAK
0.56%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

19.13%

Max
109.18%
UTHR
19.13%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

United Therapeutics (UTHR) at 38.61% converts revenue to bottom-line profit above its industry’s benchmark range, while Takeda Pharmaceutical (TAK) at 0.87% keeps roughly the typical share for its industry.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87%

Max
18.05%
Q3
4.78%
TAK
0.87%
Median
0.00%
Q1
-4.14%
Min
-17.05%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

38.61%

UTHR
38.61%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Takeda Pharmaceutical (TAK) at 24.55% and United Therapeutics (UTHR) at 28.99% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.55%

Max
83.12%
TAK
24.55%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.99%

Max
83.12%
UTHR
28.99%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR)
MetricTAKUTHR
ROE (TTM)0.56%19.13%
ROA (TTM)3.27%10.91%
Net Margin (TTM)0.87%38.61%
Operating Margin (TTM)24.55%28.99%
Gross Margin (TTM)64.77%86.34%

Growth

Revenue Growth

United Therapeutics (UTHR) at 10.61% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): A comparison of their Revenue Growth across different time periods.

EPS Growth

Takeda Pharmaceutical (TAK) at 77.96% sits in the top EPS growth quartile, while United Therapeutics (UTHR) at 13.07% is closer to the peer norm — faster per-share earnings growth for TAK.

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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR)
MetricTAKUTHR
Revenue Growth (YoY)-1.66%10.61%
Revenue Growth (3Y CAGR)3.81%18.02%
EPS Growth (YoY)77.96%13.07%
EPS Growth (3Y CAGR)-16.01%22.92%

Financial Strength

Current Ratio (MRQ)

United Therapeutics (UTHR) at 4.61 keeps current ratio within its industry’s typical mid-range, while Takeda Pharmaceutical (TAK) at 1.15 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for TAK.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.15

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TAK
1.15
Min
0.10

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.61

Max
25.13
Q3
12.13
Median
5.52
UTHR
4.61
Q1
2.47
Min
0.10
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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: Takeda Pharmaceutical (TAK) carries debt-to-equity ratio of 0.72 against its industry range, while United Therapeutics (UTHR) reports no figure this period.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.72

Max
1.42
TAK
0.72
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
UTHR
--
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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): UTHR does not report debt-to-equity ratio, so it has no value marker; TAK is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Financial Strength Metrics

Financial strength metrics for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR)
MetricTAKUTHR
Current Ratio (MRQ)1.154.61
Debt / Equity (MRQ)0.72--
Net Debt / EBITDA3.61-1.53

Dividends

Dividend Yield (TTM)

United Therapeutics (UTHR) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Takeda Pharmaceutical (TAK) reports a yield of 953.28%, ranking against industry peers normally.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

953.28%

TAK
953.28%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

UTHR
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings; United Therapeutics (UTHR) pays no dividend (payout 0.00%).

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

426.53%

TAK
426.53%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

UTHR
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR)
MetricTAKUTHR
Dividend Yield (TTM)953.28%0.00%
Dividend Payout Ratio (TTM)426.53%0.00%

Valuation

P/E Ratio (TTM)

United Therapeutics (UTHR) at 21.22 is near its industry’s usual P/E ratio, while Takeda Pharmaceutical (TAK) at 300.29 sits above its peer range — an unusually expensive price for TAK’s trailing earnings.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

300.29

TAK
300.29
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

21.22

Max
85.34
Q3
43.46
Median
26.69
UTHR
21.22
Q1
13.30
Min
0.07
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Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

Takeda Pharmaceutical (TAK) at 0.01 sits in the cheaper P/S ratio quartile while United Therapeutics (UTHR) at 7.51 prices around its industry’s middle — TAK costs less per dollar of sales, though read it alongside growth and margins.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
TAK
0.01
Min
0.01

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.51

Max
58.18
Q3
25.77
UTHR
7.51
Median
7.30
Q1
3.01
Min
0.01
Loading chart…
Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Takeda Pharmaceutical (TAK) at 1.43 sits in the lower P/B ratio quartile against book while United Therapeutics (UTHR) at 3.80 is valued near its industry’s middle — TAK is cheaper on assets, though weigh it against ROE and asset quality.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.43

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
TAK
1.43
Min
-5.59

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.80

Max
13.53
Q3
6.54
UTHR
3.80
Median
3.25
Q1
1.69
Min
-5.59
Loading chart…
Takeda Pharmaceutical (TAK) vs. United Therapeutics (UTHR): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Takeda Pharmaceutical (TAK) and United Therapeutics (UTHR)
MetricTAKUTHR
P/E Ratio (TTM)300.2921.22
P/S Ratio (TTM)0.017.51
P/B Ratio (MRQ)1.433.80
Free Cash Flow Yield (TTM)1,014.61%1.90%