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TAK vs. TMO: Takeda Pharmaceutical vs. Thermo Fisher Scientific Stock Comparison

How do Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but TAK is classified in Pharmaceuticals while TMO is classified in Life Sciences Tools & Services.

Thermo Fisher Scientific (TMO) trades as ordinary local shares, while Takeda Pharmaceutical (TAK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO)
Profile ItemTAKTMO
NameTakeda Pharmaceutical Co Ltd ADRThermo Fisher Scientific Inc.
Country/RegionJapanUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsLife Sciences Tools & Services
GICS Sub-IndustryPharmaceuticalsLife Sciences Tools & Services
Market Capitalization67.16 billion USD257.42 billion USD
CurrencyUSDUSD
ExchangeNYSENYSE
Listing DateJanuary 5, 2010March 17, 1980
Security TypeADRCommon Stock

Price Performance

Cumulative Growth

TAK
TMO
GSPC
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO)
MetricTAKTMO
Total Return (1Y)54.54%24.62%
Total Return (3Y, Annualized)18.39%17.34%
Total Return (5Y, Annualized)9.29%3.11%

Risk Profile

Drawdown History

TAK
TMO
GSPC
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Thermo Fisher Scientific (TMO) has a non-negative beta of 0.83.

Risk profile metrics for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO)
MetricTAKTMO
Volatility (1Y, Annualized)21.45%29.96%
Beta (5Y)-0.010.83
Max Drawdown (5Y)-24.83%-40.95%
Avg. Volume (3M)2.61M2.10M

Risk-Adjusted Performance

Risk-Return Positioning

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TAK and TMO are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO)
MetricTAKTMO
Sharpe Ratio (1Y)2.340.68
Sortino Ratio (1Y)3.881.02

Profitability

ROE (TTM)

Thermo Fisher Scientific (TMO) at 13.38% sits in the top ROE quartile, while Takeda Pharmaceutical (TAK) at 0.56% is closer to the peer norm — stronger capital efficiency for TMO.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.56%

Max
109.18%
Q3
6.23%
TAK
0.56%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.38%

Max
109.18%
TMO
13.38%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Thermo Fisher Scientific (TMO) at 14.94% retains a top-quartile share of revenue as profit, ahead of Takeda Pharmaceutical (TAK) at 0.87%, which keeps about the industry-typical share.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87%

Max
18.05%
Q3
4.78%
TAK
0.87%
Median
0.00%
Q1
-4.14%
Min
-17.05%

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

14.94%

Max
18.05%
TMO
14.94%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Takeda Pharmaceutical (TAK) at 24.55% and Thermo Fisher Scientific (TMO) at 20.19% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.55%

Max
83.12%
TAK
24.55%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.19%

Max
83.12%
TMO
20.19%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO)
MetricTAKTMO
ROE (TTM)0.56%13.38%
ROA (TTM)3.27%5.19%
Net Margin (TTM)0.87%14.94%
Operating Margin (TTM)24.55%20.19%
Gross Margin (TTM)64.77%41.26%

Growth

Revenue Growth

Thermo Fisher Scientific (TMO) at 3.91% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their Revenue Growth across different time periods.

EPS Growth

Takeda Pharmaceutical (TAK) at 77.96% sits in the top EPS growth quartile, while Thermo Fisher Scientific (TMO) at 7.32% is closer to the peer norm — faster per-share earnings growth for TAK.

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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO)
MetricTAKTMO
Revenue Growth (YoY)-1.66%3.91%
Revenue Growth (3Y CAGR)3.81%-0.27%
EPS Growth (YoY)77.96%7.32%
EPS Growth (3Y CAGR)-16.01%0.21%

Financial Strength

Current Ratio (MRQ)

Both Takeda Pharmaceutical (TAK) at 1.15 and Thermo Fisher Scientific (TMO) at 1.81 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.15

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TAK
1.15
Min
0.10

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.81

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TMO
1.81
Min
0.10
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both Takeda Pharmaceutical (TAK) at 0.72 and Thermo Fisher Scientific (TMO) at 0.75 lean more heavily on debt funding than most peers, landing in the higher-leverage quartile of their industries.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.72

Max
1.42
TAK
0.72
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.75

Max
1.42
TMO
0.75
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO)
MetricTAKTMO
Current Ratio (MRQ)1.151.81
Debt / Equity (MRQ)0.720.75
Net Debt / EBITDA3.612.91

Dividends

Dividend Yield (TTM)

Both Takeda Pharmaceutical (TAK) at 953.28% and Thermo Fisher Scientific (TMO) at 0.27% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

953.28%

TAK
953.28%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.27%

TMO
0.27%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings and sustainability needs extra context. Meanwhile Thermo Fisher Scientific (TMO) reports 9.70%, ranking against industry peers normally.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

426.53%

TAK
426.53%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.70%

TMO
9.70%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO)
MetricTAKTMO
Dividend Yield (TTM)953.28%0.27%
Dividend Payout Ratio (TTM)426.53%9.70%

Valuation

P/E Ratio (TTM)

Thermo Fisher Scientific (TMO) at 36.64 is near its industry’s usual P/E ratio, while Takeda Pharmaceutical (TAK) at 300.29 sits above its peer range — an unusually expensive price for TAK’s trailing earnings.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

300.29

TAK
300.29
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

36.64

Max
85.34
Q3
43.46
TMO
36.64
Median
26.69
Q1
13.30
Min
0.07
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

Takeda Pharmaceutical (TAK) at 0.01 sits in the cheaper P/S ratio quartile while Thermo Fisher Scientific (TMO) at 5.44 prices around its industry’s middle — TAK costs less per dollar of sales, though read it alongside growth and margins.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
TAK
0.01
Min
0.01

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.44

Max
58.18
Q3
25.77
Median
7.30
TMO
5.44
Q1
3.01
Min
0.01
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Takeda Pharmaceutical (TAK) at 1.43 sits in the lower P/B ratio quartile against book while Thermo Fisher Scientific (TMO) at 4.70 is valued near its industry’s middle — TAK is cheaper on assets, though weigh it against ROE and asset quality.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.43

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
TAK
1.43
Min
-5.59

TMO

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.70

Max
13.53
Q3
6.54
TMO
4.70
Median
3.25
Q1
1.69
Min
-5.59
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Takeda Pharmaceutical (TAK) vs. Thermo Fisher Scientific (TMO): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Takeda Pharmaceutical (TAK) and Thermo Fisher Scientific (TMO)
MetricTAKTMO
P/E Ratio (TTM)300.2936.64
P/S Ratio (TTM)0.015.44
P/B Ratio (MRQ)1.434.70
Free Cash Flow Yield (TTM)1,014.61%2.50%