NVS vs. TAK: Novartis vs. Takeda Pharmaceutical Stock Comparison
How do Novartis (NVS) and Takeda Pharmaceutical (TAK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Novartis (NVS) and Takeda Pharmaceutical (TAK) are both classified in the Pharmaceuticals sub-industry within the broader Pharmaceuticals industry, placing them in the closest GICS peer bucket.
Both Novartis (NVS) and Takeda Pharmaceutical (TAK) trade as ADRs — their core financials are comparable, but keep FX, depositary-program fees, and dividend withholding in view for each.
| Profile Item | NVS | TAK |
|---|---|---|
| Name | Novartis AG Sponsored ADR | Takeda Pharmaceutical Co Ltd ADR |
| Country/Region | Switzerland | Japan |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Pharmaceuticals | Pharmaceuticals |
| GICS Sub-Industry | Pharmaceuticals | Pharmaceuticals |
| Market Capitalization | 307.00 billion USD | 67.16 billion USD |
| Currency | USD | USD |
| Exchange | NYSE | NYSE |
| Listing Date | November 7, 1996 | January 5, 2010 |
| Security Type | ADR | ADR |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | NVS | TAK |
|---|---|---|
| Total Return (1Y) | 32.98% | 54.54% |
| Total Return (3Y, Annualized) | 24.72% | 18.39% |
| Total Return (5Y, Annualized) | 18.80% | 9.29% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Novartis (NVS) has a non-negative beta of 0.41.
| Metric | NVS | TAK |
|---|---|---|
| Volatility (1Y, Annualized) | 27.12% | 21.45% |
| Beta (5Y) | 0.41 | -0.01 |
| Max Drawdown (5Y) | -20.42% | -24.83% |
| Avg. Volume (3M) | 2.07M | 2.61M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | NVS | TAK |
|---|---|---|
| Sharpe Ratio (1Y) | 1.06 | 2.34 |
| Sortino Ratio (1Y) | 1.46 | 3.88 |
Profitability
ROE (TTM)
Novartis (NVS) at 24.33% sits in the top ROE quartile, while Takeda Pharmaceutical (TAK) at 0.56% is closer to the peer norm — stronger capital efficiency for NVS.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
24.33%
- Max
- 109.18%
- NVS
- 24.33%
- Q3
- 6.23%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.56%
- Max
- 109.18%
- Q3
- 6.23%
- TAK
- 0.56%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
Net Margin (TTM)
Novartis (NVS) at 17.49% retains a top-quartile share of revenue as profit, ahead of Takeda Pharmaceutical (TAK) at 0.87%, which keeps about the industry-typical share.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
17.49%
- Max
- 18.05%
- NVS
- 17.49%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.87%
- Max
- 18.05%
- Q3
- 4.78%
- TAK
- 0.87%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
Operating Margin (TTM)
Both Novartis (NVS) at 34.27% and Takeda Pharmaceutical (TAK) at 24.55% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
34.27%
- Max
- 83.12%
- NVS
- 34.27%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
24.55%
- Max
- 83.12%
- TAK
- 24.55%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
Profitability Metrics
| Metric | NVS | TAK |
|---|---|---|
| ROE (TTM) | 24.33% | 0.56% |
| ROA (TTM) | 10.86% | 3.27% |
| Net Margin (TTM) | 17.49% | 0.87% |
| Operating Margin (TTM) | 34.27% | 24.55% |
| Gross Margin (TTM) | 75.21% | 64.77% |
Growth
Revenue Growth
Novartis (NVS) at 9.57% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.
EPS Growth
Takeda Pharmaceutical (TAK) at 77.96% sits in the top EPS growth quartile, while Novartis (NVS) at 21.81% is closer to the peer norm — faster per-share earnings growth for TAK.
Growth Metrics
| Metric | NVS | TAK |
|---|---|---|
| Revenue Growth (YoY) | 9.57% | -1.66% |
| Revenue Growth (3Y CAGR) | 9.25% | 3.81% |
| EPS Growth (YoY) | 21.81% | 77.96% |
| EPS Growth (3Y CAGR) | 31.14% | -16.01% |
Financial Strength
Current Ratio (MRQ)
Both Novartis (NVS) at 0.88 and Takeda Pharmaceutical (TAK) at 1.15 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.88
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- NVS
- 0.88
- Min
- 0.10
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.15
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- TAK
- 1.15
- Min
- 0.10
Debt / Equity (MRQ)
Both Novartis (NVS) at 1.29 and Takeda Pharmaceutical (TAK) at 0.72 lean more heavily on debt funding than most peers, landing in the higher-leverage quartile of their industries.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.29
- Max
- 1.42
- NVS
- 1.29
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.72
- Max
- 1.42
- TAK
- 0.72
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
Financial Strength Metrics
| Metric | NVS | TAK |
|---|---|---|
| Current Ratio (MRQ) | 0.88 | 1.15 |
| Debt / Equity (MRQ) | 1.29 | 0.72 |
| Net Debt / EBITDA | 1.64 | 3.61 |
Dividends
Dividend Yield (TTM)
Both Novartis (NVS) at 2.88% and Takeda Pharmaceutical (TAK) at 953.28% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
2.88%
- NVS
- 2.88%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
953.28%
- TAK
- 953.28%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings and sustainability needs extra context. Meanwhile Novartis (NVS) reports 90.46%, ranking against industry peers normally.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
90.46%
- NVS
- 90.46%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
426.53%
- TAK
- 426.53%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | NVS | TAK |
|---|---|---|
| Dividend Yield (TTM) | 2.88% | 953.28% |
| Dividend Payout Ratio (TTM) | 90.46% | 426.53% |
Valuation
P/E Ratio (TTM)
Novartis (NVS) at 31.02 is near its industry’s usual P/E ratio, while Takeda Pharmaceutical (TAK) at 300.29 sits above its peer range — an unusually expensive price for TAK’s trailing earnings.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
31.02
- Max
- 85.34
- Q3
- 43.46
- NVS
- 31.02
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
300.29
- TAK
- 300.29
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
P/S Ratio (TTM)
Takeda Pharmaceutical (TAK) at 0.01 sits in the cheaper P/S ratio quartile while Novartis (NVS) at 5.35 prices around its industry’s middle — TAK costs less per dollar of sales, though read it alongside growth and margins.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
5.35
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- NVS
- 5.35
- Q1
- 3.01
- Min
- 0.01
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.01
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- Q1
- 3.01
- TAK
- 0.01
- Min
- 0.01
P/B Ratio (MRQ)
Takeda Pharmaceutical (TAK) at 1.43 looks cheap against book in the lower P/B ratio quartile, while Novartis (NVS) at 8.25 carries a premium in the upper quartile — a clear price-to-book gap.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
8.25
- Max
- 13.53
- NVS
- 8.25
- Q3
- 6.54
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.43
- Max
- 13.53
- Q3
- 6.54
- Median
- 3.25
- Q1
- 1.69
- TAK
- 1.43
- Min
- -5.59
Valuation Metrics
| Metric | NVS | TAK |
|---|---|---|
| P/E Ratio (TTM) | 31.02 | 300.29 |
| P/S Ratio (TTM) | 5.35 | 0.01 |
| P/B Ratio (MRQ) | 8.25 | 1.43 |
| Free Cash Flow Yield (TTM) | 3.67% | 1,014.61% |