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NVS vs. TAK: Novartis vs. Takeda Pharmaceutical Stock Comparison

How do Novartis (NVS) and Takeda Pharmaceutical (TAK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Novartis (NVS) and Takeda Pharmaceutical (TAK) are both classified in the Pharmaceuticals sub-industry within the broader Pharmaceuticals industry, placing them in the closest GICS peer bucket.

Both Novartis (NVS) and Takeda Pharmaceutical (TAK) trade as ADRs — their core financials are comparable, but keep FX, depositary-program fees, and dividend withholding in view for each.

Company profile comparison for Novartis (NVS) and Takeda Pharmaceutical (TAK)
Profile ItemNVSTAK
NameNovartis AG Sponsored ADRTakeda Pharmaceutical Co Ltd ADR
Country/RegionSwitzerlandJapan
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsPharmaceuticals
GICS Sub-IndustryPharmaceuticalsPharmaceuticals
Market Capitalization307.00 billion USD67.16 billion USD
CurrencyUSDUSD
ExchangeNYSENYSE
Listing DateNovember 7, 1996January 5, 2010
Security TypeADRADR

Price Performance

Cumulative Growth

NVS
TAK
GSPC
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Novartis (NVS) and Takeda Pharmaceutical (TAK). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Novartis (NVS) and Takeda Pharmaceutical (TAK). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Novartis (NVS) and Takeda Pharmaceutical (TAK)
MetricNVSTAK
Total Return (1Y)32.98%54.54%
Total Return (3Y, Annualized)24.72%18.39%
Total Return (5Y, Annualized)18.80%9.29%

Risk Profile

Drawdown History

NVS
TAK
GSPC
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Novartis (NVS) and Takeda Pharmaceutical (TAK). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Novartis (NVS) has a non-negative beta of 0.41.

Risk profile metrics for Novartis (NVS) and Takeda Pharmaceutical (TAK)
MetricNVSTAK
Volatility (1Y, Annualized)27.12%21.45%
Beta (5Y)0.41-0.01
Max Drawdown (5Y)-20.42%-24.83%
Avg. Volume (3M)2.07M2.61M

Risk-Adjusted Performance

Risk-Return Positioning

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NVS and TAK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Novartis (NVS) and Takeda Pharmaceutical (TAK)
MetricNVSTAK
Sharpe Ratio (1Y)1.062.34
Sortino Ratio (1Y)1.463.88

Profitability

ROE (TTM)

Novartis (NVS) at 24.33% sits in the top ROE quartile, while Takeda Pharmaceutical (TAK) at 0.56% is closer to the peer norm — stronger capital efficiency for NVS.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.33%

Max
109.18%
NVS
24.33%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.56%

Max
109.18%
Q3
6.23%
TAK
0.56%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Novartis (NVS) at 17.49% retains a top-quartile share of revenue as profit, ahead of Takeda Pharmaceutical (TAK) at 0.87%, which keeps about the industry-typical share.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.49%

Max
18.05%
NVS
17.49%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87%

Max
18.05%
Q3
4.78%
TAK
0.87%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Novartis (NVS) at 34.27% and Takeda Pharmaceutical (TAK) at 24.55% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

34.27%

Max
83.12%
NVS
34.27%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.55%

Max
83.12%
TAK
24.55%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Novartis (NVS) and Takeda Pharmaceutical (TAK)
MetricNVSTAK
ROE (TTM)24.33%0.56%
ROA (TTM)10.86%3.27%
Net Margin (TTM)17.49%0.87%
Operating Margin (TTM)34.27%24.55%
Gross Margin (TTM)75.21%64.77%

Growth

Revenue Growth

Novartis (NVS) at 9.57% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their Revenue Growth across different time periods.

EPS Growth

Takeda Pharmaceutical (TAK) at 77.96% sits in the top EPS growth quartile, while Novartis (NVS) at 21.81% is closer to the peer norm — faster per-share earnings growth for TAK.

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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Novartis (NVS) and Takeda Pharmaceutical (TAK)
MetricNVSTAK
Revenue Growth (YoY)9.57%-1.66%
Revenue Growth (3Y CAGR)9.25%3.81%
EPS Growth (YoY)21.81%77.96%
EPS Growth (3Y CAGR)31.14%-16.01%

Financial Strength

Current Ratio (MRQ)

Both Novartis (NVS) at 0.88 and Takeda Pharmaceutical (TAK) at 1.15 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.88

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
NVS
0.88
Min
0.10

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.15

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TAK
1.15
Min
0.10
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both Novartis (NVS) at 1.29 and Takeda Pharmaceutical (TAK) at 0.72 lean more heavily on debt funding than most peers, landing in the higher-leverage quartile of their industries.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.29

Max
1.42
NVS
1.29
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.72

Max
1.42
TAK
0.72
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Novartis (NVS) and Takeda Pharmaceutical (TAK)
MetricNVSTAK
Current Ratio (MRQ)0.881.15
Debt / Equity (MRQ)1.290.72
Net Debt / EBITDA1.643.61

Dividends

Dividend Yield (TTM)

Both Novartis (NVS) at 2.88% and Takeda Pharmaceutical (TAK) at 953.28% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.88%

NVS
2.88%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

953.28%

TAK
953.28%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings and sustainability needs extra context. Meanwhile Novartis (NVS) reports 90.46%, ranking against industry peers normally.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

90.46%

NVS
90.46%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

426.53%

TAK
426.53%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Novartis (NVS) and Takeda Pharmaceutical (TAK)
MetricNVSTAK
Dividend Yield (TTM)2.88%953.28%
Dividend Payout Ratio (TTM)90.46%426.53%

Valuation

P/E Ratio (TTM)

Novartis (NVS) at 31.02 is near its industry’s usual P/E ratio, while Takeda Pharmaceutical (TAK) at 300.29 sits above its peer range — an unusually expensive price for TAK’s trailing earnings.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

31.02

Max
85.34
Q3
43.46
NVS
31.02
Median
26.69
Q1
13.30
Min
0.07

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

300.29

TAK
300.29
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

Takeda Pharmaceutical (TAK) at 0.01 sits in the cheaper P/S ratio quartile while Novartis (NVS) at 5.35 prices around its industry’s middle — TAK costs less per dollar of sales, though read it alongside growth and margins.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.35

Max
58.18
Q3
25.77
Median
7.30
NVS
5.35
Q1
3.01
Min
0.01

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
TAK
0.01
Min
0.01
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Takeda Pharmaceutical (TAK) at 1.43 looks cheap against book in the lower P/B ratio quartile, while Novartis (NVS) at 8.25 carries a premium in the upper quartile — a clear price-to-book gap.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.25

Max
13.53
NVS
8.25
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.43

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
TAK
1.43
Min
-5.59
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Novartis (NVS) vs. Takeda Pharmaceutical (TAK): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Novartis (NVS) and Takeda Pharmaceutical (TAK)
MetricNVSTAK
P/E Ratio (TTM)31.02300.29
P/S Ratio (TTM)5.350.01
P/B Ratio (MRQ)8.251.43
Free Cash Flow Yield (TTM)3.67%1,014.61%