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NVS vs. REGN: Novartis vs. Regeneron Pharmaceuticals Stock Comparison

How do Novartis (NVS) and Regeneron Pharmaceuticals (REGN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Novartis (NVS) and Regeneron Pharmaceuticals (REGN) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but NVS is classified in Pharmaceuticals while REGN is classified in Biotechnology.

Regeneron Pharmaceuticals (REGN) trades as ordinary local shares, while Novartis (NVS) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for Novartis (NVS) and Regeneron Pharmaceuticals (REGN)
Profile ItemNVSREGN
NameNovartis AG Sponsored ADRRegeneron Pharmaceuticals, Inc.
Country/RegionSwitzerlandUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsBiotechnology
GICS Sub-IndustryPharmaceuticalsBiotechnology
Market Capitalization307.00 billion USD93.55 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateNovember 7, 1996April 2, 1991
Security TypeADRCommon Stock

Price Performance

Cumulative Growth

NVS
REGN
GSPC
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Novartis (NVS) and Regeneron Pharmaceuticals (REGN). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Novartis (NVS) and Regeneron Pharmaceuticals (REGN). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Novartis (NVS) and Regeneron Pharmaceuticals (REGN)
MetricNVSREGN
Total Return (1Y)32.98%40.87%
Total Return (3Y, Annualized)24.72%5.15%
Total Return (5Y, Annualized)18.80%8.58%

Risk Profile

Drawdown History

NVS
REGN
GSPC
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Novartis (NVS) and Regeneron Pharmaceuticals (REGN). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Novartis (NVS) and Regeneron Pharmaceuticals (REGN)
MetricNVSREGN
Volatility (1Y, Annualized)27.12%34.08%
Beta (5Y)0.410.10
Max Drawdown (5Y)-20.42%-59.69%
Avg. Volume (3M)2.07M772.95K

Risk-Adjusted Performance

Risk-Return Positioning

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NVS and REGN are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Novartis (NVS) and Regeneron Pharmaceuticals (REGN)
MetricNVSREGN
Sharpe Ratio (1Y)1.061.07
Sortino Ratio (1Y)1.461.70

Profitability

ROE (TTM)

Both Novartis (NVS) at 24.33% and Regeneron Pharmaceuticals (REGN) at 14.95% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.33%

Max
109.18%
NVS
24.33%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

14.95%

Max
109.18%
REGN
14.95%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Regeneron Pharmaceuticals (REGN) at 28.51% keeps the most of each sales dollar — above its industry’s net margin range — and Novartis (NVS) at 17.49% also retains a top-quartile share.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.49%

Max
18.05%
NVS
17.49%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.51%

REGN
28.51%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Novartis (NVS) at 34.27% and Regeneron Pharmaceuticals (REGN) at 40.46% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

34.27%

Max
83.12%
NVS
34.27%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

40.46%

Max
83.12%
REGN
40.46%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Novartis (NVS) and Regeneron Pharmaceuticals (REGN)
MetricNVSREGN
ROE (TTM)24.33%14.95%
ROA (TTM)10.86%7.59%
Net Margin (TTM)17.49%28.51%
Operating Margin (TTM)34.27%40.46%
Gross Margin (TTM)75.21%46.73%

Growth

Revenue Growth

Both Novartis (NVS) at 9.57% and Regeneron Pharmaceuticals (REGN) at 0.99% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their Revenue Growth across different time periods.

EPS Growth

Both Novartis (NVS) at 21.81% and Regeneron Pharmaceuticals (REGN) at 8.19% land near their industries' usual EPS growth ranges, so bottom-line momentum looks broadly in line with peers on both sides.

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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Novartis (NVS) and Regeneron Pharmaceuticals (REGN)
MetricNVSREGN
Revenue Growth (YoY)9.57%0.99%
Revenue Growth (3Y CAGR)9.25%5.62%
EPS Growth (YoY)21.81%8.19%
EPS Growth (3Y CAGR)31.14%2.77%

Financial Strength

Current Ratio (MRQ)

Regeneron Pharmaceuticals (REGN) at 3.35 keeps current ratio within its industry’s typical mid-range, while Novartis (NVS) at 0.88 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for NVS.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.88

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
NVS
0.88
Min
0.10

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.35

Max
25.13
Q3
12.13
Median
5.52
REGN
3.35
Q1
2.47
Min
0.10
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Regeneron Pharmaceuticals (REGN) at 0.08 carries an industry-typical debt-to-equity mix, while Novartis (NVS) at 1.29 uses more debt funding than most peers.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.29

Max
1.42
NVS
1.29
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.08

Max
1.42
Q3
0.65
Median
0.15
REGN
0.08
Q1
0.02
Min
0.00
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Novartis (NVS) and Regeneron Pharmaceuticals (REGN)
MetricNVSREGN
Current Ratio (MRQ)0.883.35
Debt / Equity (MRQ)1.290.08
Net Debt / EBITDA1.64-1.17

Dividends

Dividend Yield (TTM)

Both Novartis (NVS) at 2.88% and Regeneron Pharmaceuticals (REGN) at 0.41% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.88%

NVS
2.88%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.41%

REGN
0.41%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Both Novartis (NVS) at 90.46% and Regeneron Pharmaceuticals (REGN) at 8.18% pay out more of their earnings than any of their industry peers — the thinnest cover in their groups, so dividend headroom deserves attention.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

90.46%

NVS
90.46%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.18%

REGN
8.18%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Novartis (NVS) and Regeneron Pharmaceuticals (REGN)
MetricNVSREGN
Dividend Yield (TTM)2.88%0.41%
Dividend Payout Ratio (TTM)90.46%8.18%

Valuation

P/E Ratio (TTM)

Both Novartis (NVS) at 31.02 and Regeneron Pharmaceuticals (REGN) at 19.99 land around their industries’ usual P/E ratio levels — neither is getting a clear earnings-multiple discount or premium versus peers.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

31.02

Max
85.34
Q3
43.46
NVS
31.02
Median
26.69
Q1
13.30
Min
0.07

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

19.99

Max
85.34
Q3
43.46
Median
26.69
REGN
19.99
Q1
13.30
Min
0.07
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Novartis (NVS) at 5.35 and Regeneron Pharmaceuticals (REGN) at 5.54 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.35

Max
58.18
Q3
25.77
Median
7.30
NVS
5.35
Q1
3.01
Min
0.01

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.54

Max
58.18
Q3
25.77
Median
7.30
REGN
5.54
Q1
3.01
Min
0.01
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Regeneron Pharmaceuticals (REGN) at 2.71 is valued about in line with its industry on P/B ratio, while Novartis (NVS) at 8.25 carries an above-peer premium to book — NVS is pricier on assets.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.25

Max
13.53
NVS
8.25
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.71

Max
13.53
Q3
6.54
Median
3.25
REGN
2.71
Q1
1.69
Min
-5.59
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Novartis (NVS) vs. Regeneron Pharmaceuticals (REGN): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Novartis (NVS) and Regeneron Pharmaceuticals (REGN)
MetricNVSREGN
P/E Ratio (TTM)31.0219.99
P/S Ratio (TTM)5.355.54
P/B Ratio (MRQ)8.252.71
Free Cash Flow Yield (TTM)3.67%2.76%