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MTD vs. VRTX: Mettler-Toledo vs. Vertex Pharmaceuticals Stock Comparison

How do Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but MTD is classified in Life Sciences Tools & Services while VRTX is classified in Biotechnology.

Company profile comparison for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX)
Profile ItemMTDVRTX
NameMettler-Toledo International Inc.Vertex Pharmaceuticals Incorporated Common Stock
Country/RegionSwitzerlandUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesBiotechnology
GICS Sub-IndustryLife Sciences Tools & ServicesBiotechnology
Market Capitalization34.25 billion USD138.71 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateNovember 14, 1997July 24, 1991
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

MTD
VRTX
GSPC
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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX)
MetricMTDVRTX
Total Return (1Y)21.58%34.89%
Total Return (3Y, Annualized)19.54%14.44%
Total Return (5Y, Annualized)2.36%23.65%

Risk Profile

Drawdown History

MTD
VRTX
GSPC
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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX)
MetricMTDVRTX
Volatility (1Y, Annualized)31.70%29.73%
Beta (5Y)1.150.29
Max Drawdown (5Y)-43.47%-29.07%
Avg. Volume (3M)197.80K1.25M

Risk-Adjusted Performance

Risk-Return Positioning

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MTD and VRTX are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX)
MetricMTDVRTX
Sharpe Ratio (1Y)0.551.03
Sortino Ratio (1Y)0.751.68

Profitability

ROE (TTM)

Capital efficiency shows on one side only: Vertex Pharmaceuticals (VRTX) earns 20.80% on shareholders’ equity, ranked against its industry; Mettler-Toledo (MTD) has no ROE this period.

MTD

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
MTD
--

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.80%

Max
109.18%
VRTX
20.80%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): MTD does not report ROE, so it has no value marker; VRTX is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Net Margin (TTM)

Both Mettler-Toledo (MTD) at 22.25% and Vertex Pharmaceuticals (VRTX) at 30.70% keep an unusually large share of revenue as bottom-line profit — each net margin clears its industry’s benchmark range.

MTD

Pharmaceuticals, Biotechnology & Life Sciences industry group

22.25%

MTD
22.25%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

30.70%

VRTX
30.70%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Mettler-Toledo (MTD) at 28.70% and Vertex Pharmaceuticals (VRTX) at 35.57% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

MTD

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.70%

Max
83.12%
MTD
28.70%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.57%

Max
83.12%
VRTX
35.57%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX)
MetricMTDVRTX
ROE (TTM)--20.80%
ROA (TTM)20.09%10.62%
Net Margin (TTM)22.25%30.70%
Operating Margin (TTM)28.70%35.57%
Gross Margin (TTM)59.16%54.81%

Growth

Revenue Growth

Both Mettler-Toledo (MTD) at 3.98% and Vertex Pharmaceuticals (VRTX) at 8.90% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Mettler-Toledo (MTD) reports EPS growth of 3.88%, ranked against its industry; Vertex Pharmaceuticals (VRTX) has no EPS growth figure this period.

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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX)
MetricMTDVRTX
Revenue Growth (YoY)3.98%8.90%
Revenue Growth (3Y CAGR)0.90%10.35%
EPS Growth (YoY)3.88%--
EPS Growth (3Y CAGR)3.06%6.12%

Financial Strength

Current Ratio (MRQ)

Both Mettler-Toledo (MTD) at 1.10 and Vertex Pharmaceuticals (VRTX) at 2.34 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

MTD

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.10

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
MTD
1.10
Min
0.10

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.34

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
VRTX
2.34
Min
0.10
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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Vertex Pharmaceuticals (VRTX) at 0.31 is near its industry mid-range for debt-to-equity ratio, while Mettler-Toledo (MTD) at 26.06 sits above its benchmark range, pointing to a heavier debt load relative to equity.

MTD

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.06

MTD
26.06
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.31

Max
1.42
Q3
0.65
VRTX
0.31
Median
0.15
Q1
0.02
Min
0.00
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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX)
MetricMTDVRTX
Current Ratio (MRQ)1.102.34
Debt / Equity (MRQ)26.060.31
Net Debt / EBITDA1.580.03

Dividends

Dividend Yield (TTM)

Neither Mettler-Toledo (MTD) nor Vertex Pharmaceuticals (VRTX) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

MTD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

MTD
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

VRTX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Mettler-Toledo (MTD) nor Vertex Pharmaceuticals (VRTX) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

MTD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

MTD
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

VRTX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX)
MetricMTDVRTX
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

Both Mettler-Toledo (MTD) at 37.38 and Vertex Pharmaceuticals (VRTX) at 35.21 land around their industries’ usual P/E ratio levels — neither is getting a clear earnings-multiple discount or premium versus peers.

MTD

Pharmaceuticals, Biotechnology & Life Sciences industry group

37.38

Max
85.34
Q3
43.46
MTD
37.38
Median
26.69
Q1
13.30
Min
0.07

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.21

Max
85.34
Q3
43.46
VRTX
35.21
Median
26.69
Q1
13.30
Min
0.07
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Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Mettler-Toledo (MTD) at 8.16 and Vertex Pharmaceuticals (VRTX) at 10.71 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

MTD

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.16

Max
58.18
Q3
25.77
MTD
8.16
Median
7.30
Q1
3.01
Min
0.01

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.71

Max
58.18
Q3
25.77
VRTX
10.71
Median
7.30
Q1
3.01
Min
0.01
Loading chart…
Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Both look rich against book: Vertex Pharmaceuticals (VRTX) at 6.63 sits in the upper P/B ratio quartile, and Mettler-Toledo (MTD) at 442.71 prices even higher, above its industry range.

MTD

Pharmaceuticals, Biotechnology & Life Sciences industry group

442.71

MTD
442.71
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.63

Max
13.53
VRTX
6.63
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
Loading chart…
Mettler-Toledo (MTD) vs. Vertex Pharmaceuticals (VRTX): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Mettler-Toledo (MTD) and Vertex Pharmaceuticals (VRTX)
MetricMTDVRTX
P/E Ratio (TTM)37.3835.21
P/S Ratio (TTM)8.1610.71
P/B Ratio (MRQ)442.716.63
Free Cash Flow Yield (TTM)1.97%1.69%