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ILMN vs. UTHR: Illumina vs. United Therapeutics Stock Comparison

How do Illumina (ILMN) and United Therapeutics (UTHR) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Illumina (ILMN) and United Therapeutics (UTHR) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ILMN is classified in Life Sciences Tools & Services while UTHR is classified in Biotechnology.

Company profile comparison for Illumina (ILMN) and United Therapeutics (UTHR)
Profile ItemILMNUTHR
NameIllumina Inc.United Therapeutics Corporation
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesBiotechnology
GICS Sub-IndustryLife Sciences Tools & ServicesBiotechnology
Market Capitalization32.23 billion USD23.94 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateJuly 28, 2000June 17, 1999
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

ILMN
UTHR
GSPC
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Illumina (ILMN) vs. United Therapeutics (UTHR), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Illumina (ILMN) and United Therapeutics (UTHR). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Illumina (ILMN) and United Therapeutics (UTHR). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Illumina (ILMN) and United Therapeutics (UTHR)
MetricILMNUTHR
Total Return (1Y)79.70%28.77%
Total Return (3Y, Annualized)28.16%37.63%
Total Return (5Y, Annualized)-10.65%23.78%

Risk Profile

Drawdown History

ILMN
UTHR
GSPC
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Illumina (ILMN) vs. United Therapeutics (UTHR), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Illumina (ILMN) and United Therapeutics (UTHR). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Illumina (ILMN) has an aggressive beta of 1.46, indicating higher sensitivity to broad-market moves, while United Therapeutics (UTHR) is defensive at 0.49 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Illumina (ILMN) and United Therapeutics (UTHR)
MetricILMNUTHR
Volatility (1Y, Annualized)48.47%35.00%
Beta (5Y)1.460.49
Max Drawdown (5Y)-82.95%-33.00%
Avg. Volume (3M)2.77M694.55K

Risk-Adjusted Performance

Risk-Return Positioning

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ILMN and UTHR are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Illumina (ILMN) and United Therapeutics (UTHR)
MetricILMNUTHR
Sharpe Ratio (1Y)1.560.70
Sortino Ratio (1Y)2.251.29

Profitability

ROE (TTM)

Both Illumina (ILMN) at 32.39% and United Therapeutics (UTHR) at 19.13% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.39%

Max
109.18%
ILMN
32.39%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

19.13%

Max
109.18%
UTHR
19.13%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Illumina (ILMN) vs. United Therapeutics (UTHR): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Both Illumina (ILMN) at 19.72% and United Therapeutics (UTHR) at 38.61% keep an unusually large share of revenue as bottom-line profit — each net margin clears its industry’s benchmark range.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

19.72%

ILMN
19.72%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

38.61%

UTHR
38.61%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Illumina (ILMN) vs. United Therapeutics (UTHR): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Illumina (ILMN) at 20.02% and United Therapeutics (UTHR) at 28.99% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.02%

Max
83.12%
ILMN
20.02%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.99%

Max
83.12%
UTHR
28.99%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Illumina (ILMN) vs. United Therapeutics (UTHR): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Illumina (ILMN) and United Therapeutics (UTHR)
MetricILMNUTHR
ROE (TTM)32.39%19.13%
ROA (TTM)8.32%10.91%
Net Margin (TTM)19.72%38.61%
Operating Margin (TTM)20.02%28.99%
Gross Margin (TTM)67.68%86.34%

Growth

Revenue Growth

United Therapeutics (UTHR) at 10.61% is around its peer norm for revenue growth, while Illumina (ILMN) at -0.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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Illumina (ILMN) vs. United Therapeutics (UTHR): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: United Therapeutics (UTHR) reports EPS growth of 13.07%, ranked against its industry; Illumina (ILMN) has no EPS growth figure this period.

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Illumina (ILMN) vs. United Therapeutics (UTHR): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Illumina (ILMN) and United Therapeutics (UTHR)
MetricILMNUTHR
Revenue Growth (YoY)-0.66%10.61%
Revenue Growth (3Y CAGR)-1.78%18.02%
EPS Growth (YoY)--13.07%
EPS Growth (3Y CAGR)--22.92%

Financial Strength

Current Ratio (MRQ)

Both Illumina (ILMN) at 2.63 and United Therapeutics (UTHR) at 4.61 carry current ratio within their industries’ typical mid-ranges, suggesting balanced short-term liquidity relative to peers.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.63

Max
25.13
Q3
12.13
Median
5.52
ILMN
2.63
Q1
2.47
Min
0.10

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.61

Max
25.13
Q3
12.13
Median
5.52
UTHR
4.61
Q1
2.47
Min
0.10
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Illumina (ILMN) vs. United Therapeutics (UTHR): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: Illumina (ILMN) carries debt-to-equity ratio of 0.74 against its industry range, while United Therapeutics (UTHR) reports no figure this period.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.74

Max
1.42
ILMN
0.74
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
UTHR
--
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Illumina (ILMN) vs. United Therapeutics (UTHR): UTHR does not report debt-to-equity ratio, so it has no value marker; ILMN is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Financial Strength Metrics

Financial strength metrics for Illumina (ILMN) and United Therapeutics (UTHR)
MetricILMNUTHR
Current Ratio (MRQ)2.634.61
Debt / Equity (MRQ)0.74--
Net Debt / EBITDA0.85-1.53

Dividends

Dividend Yield (TTM)

Neither Illumina (ILMN) nor United Therapeutics (UTHR) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ILMN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

UTHR
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Illumina (ILMN) vs. United Therapeutics (UTHR): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Illumina (ILMN) nor United Therapeutics (UTHR) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ILMN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

UTHR
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Illumina (ILMN) vs. United Therapeutics (UTHR): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Illumina (ILMN) and United Therapeutics (UTHR)
MetricILMNUTHR
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

Both Illumina (ILMN) at 36.68 and United Therapeutics (UTHR) at 21.22 land around their industries’ usual P/E ratio levels — neither is getting a clear earnings-multiple discount or premium versus peers.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

36.68

Max
85.34
Q3
43.46
ILMN
36.68
Median
26.69
Q1
13.30
Min
0.07

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

21.22

Max
85.34
Q3
43.46
Median
26.69
UTHR
21.22
Q1
13.30
Min
0.07
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Illumina (ILMN) vs. United Therapeutics (UTHR): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Illumina (ILMN) at 7.10 and United Therapeutics (UTHR) at 7.51 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.10

Max
58.18
Q3
25.77
Median
7.30
ILMN
7.10
Q1
3.01
Min
0.01

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.51

Max
58.18
Q3
25.77
UTHR
7.51
Median
7.30
Q1
3.01
Min
0.01
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Illumina (ILMN) vs. United Therapeutics (UTHR): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

United Therapeutics (UTHR) at 3.80 is valued about in line with its industry on P/B ratio, while Illumina (ILMN) at 10.30 carries an above-peer premium to book — ILMN is pricier on assets.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.30

Max
13.53
ILMN
10.30
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

UTHR

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.80

Max
13.53
Q3
6.54
UTHR
3.80
Median
3.25
Q1
1.69
Min
-5.59
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Illumina (ILMN) vs. United Therapeutics (UTHR): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Illumina (ILMN) and United Therapeutics (UTHR)
MetricILMNUTHR
P/E Ratio (TTM)36.6821.22
P/S Ratio (TTM)7.107.51
P/B Ratio (MRQ)10.303.80
Free Cash Flow Yield (TTM)2.67%1.90%