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ILMN vs. NVO: Illumina vs. Novo Nordisk Stock Comparison

How do Illumina (ILMN) and Novo Nordisk (NVO) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Illumina (ILMN) and Novo Nordisk (NVO) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ILMN is classified in Life Sciences Tools & Services while NVO is classified in Pharmaceuticals.

Illumina (ILMN) trades as ordinary local shares, while Novo Nordisk (NVO) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for Illumina (ILMN) and Novo Nordisk (NVO)
Profile ItemILMNNVO
NameIllumina Inc.Novo Nordisk A/S Sponsored ADR
Country/RegionUnited StatesDenmark
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesPharmaceuticals
GICS Sub-IndustryLife Sciences Tools & ServicesPharmaceuticals
Market Capitalization32.23 billion USD177.74 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateJuly 28, 2000April 30, 1981
Security TypeCommon StockADR

Price Performance

Cumulative Growth

ILMN
NVO
GSPC
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Illumina (ILMN) vs. Novo Nordisk (NVO), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Illumina (ILMN) and Novo Nordisk (NVO). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Illumina (ILMN) and Novo Nordisk (NVO). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Illumina (ILMN) and Novo Nordisk (NVO)
MetricILMNNVO
Total Return (1Y)79.70%-5.29%
Total Return (3Y, Annualized)28.16%-23.41%
Total Return (5Y, Annualized)-10.65%-4.13%

Risk Profile

Drawdown History

ILMN
NVO
GSPC
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Illumina (ILMN) vs. Novo Nordisk (NVO), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Illumina (ILMN) and Novo Nordisk (NVO). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Illumina (ILMN) has an aggressive beta of 1.46, indicating higher sensitivity to broad-market moves, while Novo Nordisk (NVO) is defensive at 0.67 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Illumina (ILMN) and Novo Nordisk (NVO)
MetricILMNNVO
Volatility (1Y, Annualized)48.47%45.98%
Beta (5Y)1.460.67
Max Drawdown (5Y)-82.95%-74.70%
Avg. Volume (3M)2.77M12.11M

Risk-Adjusted Performance

Risk-Return Positioning

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ILMN and NVO are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Illumina (ILMN) and Novo Nordisk (NVO)
MetricILMNNVO
Sharpe Ratio (1Y)1.56-0.21
Sortino Ratio (1Y)2.25-0.28

Profitability

ROE (TTM)

Both Illumina (ILMN) at 32.39% and Novo Nordisk (NVO) at 58.38% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.39%

Max
109.18%
ILMN
32.39%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

58.38%

Max
109.18%
NVO
58.38%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Both Illumina (ILMN) at 19.72% and Novo Nordisk (NVO) at 33.92% keep an unusually large share of revenue as bottom-line profit — each net margin clears its industry’s benchmark range.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

19.72%

ILMN
19.72%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

33.92%

NVO
33.92%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Illumina (ILMN) at 20.02% and Novo Nordisk (NVO) at 40.05% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.02%

Max
83.12%
ILMN
20.02%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

40.05%

Max
83.12%
NVO
40.05%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Illumina (ILMN) and Novo Nordisk (NVO)
MetricILMNNVO
ROE (TTM)32.39%58.38%
ROA (TTM)8.32%19.05%
Net Margin (TTM)19.72%33.92%
Operating Margin (TTM)20.02%40.05%
Gross Margin (TTM)67.68%83.33%

Growth

Revenue Growth

Novo Nordisk (NVO) at 6.43% is around its peer norm for revenue growth, while Illumina (ILMN) at -0.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Novo Nordisk (NVO) reports EPS growth of 1.77%, ranked against its industry; Illumina (ILMN) has no EPS growth figure this period.

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Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Illumina (ILMN) and Novo Nordisk (NVO)
MetricILMNNVO
Revenue Growth (YoY)-0.66%6.43%
Revenue Growth (3Y CAGR)-1.78%20.43%
EPS Growth (YoY)--1.77%
EPS Growth (3Y CAGR)--23.52%

Financial Strength

Current Ratio (MRQ)

Illumina (ILMN) at 2.63 keeps current ratio within its industry’s typical mid-range, while Novo Nordisk (NVO) at 0.85 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for NVO.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.63

Max
25.13
Q3
12.13
Median
5.52
ILMN
2.63
Q1
2.47
Min
0.10

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.85

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
NVO
0.85
Min
0.10
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Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Novo Nordisk (NVO) at 0.62 carries an industry-typical debt-to-equity mix, while Illumina (ILMN) at 0.74 uses more debt funding than most peers.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.74

Max
1.42
ILMN
0.74
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.62

Max
1.42
Q3
0.65
NVO
0.62
Median
0.15
Q1
0.02
Min
0.00
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Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Illumina (ILMN) and Novo Nordisk (NVO)
MetricILMNNVO
Current Ratio (MRQ)2.630.85
Debt / Equity (MRQ)0.740.62
Net Debt / EBITDA0.850.49

Dividends

Dividend Yield (TTM)

Illumina (ILMN) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Novo Nordisk (NVO) reports a yield of 29.03%, ranking against industry peers normally.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ILMN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

29.03%

NVO
29.03%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Illumina (ILMN) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Novo Nordisk (NVO) reports a payout of 45.36%, ranking against industry peers normally.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ILMN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

45.36%

NVO
45.36%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Illumina (ILMN) and Novo Nordisk (NVO)
MetricILMNNVO
Dividend Yield (TTM)0.00%29.03%
Dividend Payout Ratio (TTM)0.00%45.36%

Valuation

P/E Ratio (TTM)

Novo Nordisk (NVO) at 10.18 sits in the cheaper P/E ratio quartile, while Illumina (ILMN) at 36.68 is closer to its industry’s usual earnings multiple — a discount for NVO, though growth and earnings durability still matter.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

36.68

Max
85.34
Q3
43.46
ILMN
36.68
Median
26.69
Q1
13.30
Min
0.07

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.18

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
NVO
10.18
Min
0.07
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Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

Novo Nordisk (NVO) at 0.53 sits in the cheaper P/S ratio quartile while Illumina (ILMN) at 7.10 prices around its industry’s middle — NVO costs less per dollar of sales, though read it alongside growth and margins.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.10

Max
58.18
Q3
25.77
Median
7.30
ILMN
7.10
Q1
3.01
Min
0.01

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.53

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
NVO
0.53
Min
0.01
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Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Novo Nordisk (NVO) at 5.43 is valued about in line with its industry on P/B ratio, while Illumina (ILMN) at 10.30 carries an above-peer premium to book — ILMN is pricier on assets.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.30

Max
13.53
ILMN
10.30
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

NVO

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.43

Max
13.53
Q3
6.54
NVO
5.43
Median
3.25
Q1
1.69
Min
-5.59
Loading chart…
Illumina (ILMN) vs. Novo Nordisk (NVO): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Illumina (ILMN) and Novo Nordisk (NVO)
MetricILMNNVO
P/E Ratio (TTM)36.6810.18
P/S Ratio (TTM)7.100.53
P/B Ratio (MRQ)10.305.43
Free Cash Flow Yield (TTM)2.67%18.43%