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GSK vs. TAK: GSK vs. Takeda Pharmaceutical Stock Comparison

How do GSK (GSK) and Takeda Pharmaceutical (TAK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

GSK (GSK) and Takeda Pharmaceutical (TAK) are both classified in the Pharmaceuticals sub-industry within the broader Pharmaceuticals industry, placing them in the closest GICS peer bucket.

Both GSK (GSK) and Takeda Pharmaceutical (TAK) trade as ADRs — their core financials are comparable, but keep FX, depositary-program fees, and dividend withholding in view for each.

Company profile comparison for GSK (GSK) and Takeda Pharmaceutical (TAK)
Profile ItemGSKTAK
NameGSK plc ADRTakeda Pharmaceutical Co Ltd ADR
Country/RegionUnited KingdomJapan
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsPharmaceuticals
GICS Sub-IndustryPharmaceuticalsPharmaceuticals
Market Capitalization100.88 billion USD67.16 billion USD
CurrencyUSDUSD
ExchangeNYSENYSE
Listing DateMarch 28, 1980January 5, 2010
Security TypeADRADR

Price Performance

Cumulative Growth

GSK
TAK
GSPC
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GSK (GSK) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for GSK (GSK) and Takeda Pharmaceutical (TAK). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for GSK (GSK) and Takeda Pharmaceutical (TAK). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for GSK (GSK) and Takeda Pharmaceutical (TAK)
MetricGSKTAK
Total Return (1Y)13.73%54.54%
Total Return (3Y, Annualized)18.65%18.39%
Total Return (5Y, Annualized)7.97%9.29%

Risk Profile

Drawdown History

GSK
TAK
GSPC
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GSK (GSK) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for GSK (GSK) and Takeda Pharmaceutical (TAK). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. GSK (GSK) has a non-negative beta of 0.31.

Risk profile metrics for GSK (GSK) and Takeda Pharmaceutical (TAK)
MetricGSKTAK
Volatility (1Y, Annualized)26.25%21.45%
Beta (5Y)0.31-0.01
Max Drawdown (5Y)-37.63%-24.83%
Avg. Volume (3M)4.05M2.61M

Risk-Adjusted Performance

Risk-Return Positioning

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GSK and TAK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for GSK (GSK) and Takeda Pharmaceutical (TAK)
MetricGSKTAK
Sharpe Ratio (1Y)0.362.34
Sortino Ratio (1Y)0.563.88

Profitability

ROE (TTM)

GSK (GSK) at 28.27% sits in the top ROE quartile, while Takeda Pharmaceutical (TAK) at 0.56% is closer to the peer norm — stronger capital efficiency for GSK.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.27%

Max
109.18%
GSK
28.27%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.56%

Max
109.18%
Q3
6.23%
TAK
0.56%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

GSK (GSK) at 12.97% retains a top-quartile share of revenue as profit, ahead of Takeda Pharmaceutical (TAK) at 0.87%, which keeps about the industry-typical share.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

12.97%

Max
18.05%
GSK
12.97%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87%

Max
18.05%
Q3
4.78%
TAK
0.87%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both GSK (GSK) at 32.14% and Takeda Pharmaceutical (TAK) at 24.55% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.14%

Max
83.12%
GSK
32.14%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.55%

Max
83.12%
TAK
24.55%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for GSK (GSK) and Takeda Pharmaceutical (TAK)
MetricGSKTAK
ROE (TTM)28.27%0.56%
ROA (TTM)9.24%3.27%
Net Margin (TTM)12.97%0.87%
Operating Margin (TTM)32.14%24.55%
Gross Margin (TTM)73.79%64.77%

Growth

Revenue Growth

GSK (GSK) at 4.11% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their Revenue Growth across different time periods.

EPS Growth

Both GSK (GSK) at 123.15% and Takeda Pharmaceutical (TAK) at 77.96% sit in the top peer quartile for EPS growth, so each is compounding per-share earnings faster than typical industry peers.

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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for GSK (GSK) and Takeda Pharmaceutical (TAK)
MetricGSKTAK
Revenue Growth (YoY)4.11%-1.66%
Revenue Growth (3Y CAGR)3.66%3.81%
EPS Growth (YoY)123.15%77.96%
EPS Growth (3Y CAGR)-27.63%-16.01%

Financial Strength

Current Ratio (MRQ)

Both GSK (GSK) at 0.86 and Takeda Pharmaceutical (TAK) at 1.15 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.86

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
GSK
0.86
Min
0.10

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.15

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TAK
1.15
Min
0.10
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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both GSK (GSK) at 1.30 and Takeda Pharmaceutical (TAK) at 0.72 lean more heavily on debt funding than most peers, landing in the higher-leverage quartile of their industries.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.30

Max
1.42
GSK
1.30
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.72

Max
1.42
TAK
0.72
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for GSK (GSK) and Takeda Pharmaceutical (TAK)
MetricGSKTAK
Current Ratio (MRQ)0.861.15
Debt / Equity (MRQ)1.300.72
Net Debt / EBITDA1.883.61

Dividends

Dividend Yield (TTM)

Both GSK (GSK) at 1.57% and Takeda Pharmaceutical (TAK) at 953.28% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.57%

GSK
1.57%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

953.28%

TAK
953.28%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings and sustainability needs extra context. Meanwhile GSK (GSK) reports 63.33%, ranking against industry peers normally.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

63.33%

GSK
63.33%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

426.53%

TAK
426.53%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for GSK (GSK) and Takeda Pharmaceutical (TAK)
MetricGSKTAK
Dividend Yield (TTM)1.57%953.28%
Dividend Payout Ratio (TTM)63.33%426.53%

Valuation

P/E Ratio (TTM)

GSK (GSK) at 17.54 is near its industry’s usual P/E ratio, while Takeda Pharmaceutical (TAK) at 300.29 sits above its peer range — an unusually expensive price for TAK’s trailing earnings.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.54

Max
85.34
Q3
43.46
Median
26.69
GSK
17.54
Q1
13.30
Min
0.07

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

300.29

TAK
300.29
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

Both GSK (GSK) at 3.01 and Takeda Pharmaceutical (TAK) at 0.01 fetch a relatively low price per dollar of sales, landing in the cheaper P/S ratio quartile of their industries.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
GSK
3.01
Min
0.01

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
TAK
0.01
Min
0.01
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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Takeda Pharmaceutical (TAK) at 1.43 sits in the lower P/B ratio quartile against book while GSK (GSK) at 4.02 is valued near its industry’s middle — TAK is cheaper on assets, though weigh it against ROE and asset quality.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.02

Max
13.53
Q3
6.54
GSK
4.02
Median
3.25
Q1
1.69
Min
-5.59

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.43

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
TAK
1.43
Min
-5.59
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GSK (GSK) vs. Takeda Pharmaceutical (TAK): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for GSK (GSK) and Takeda Pharmaceutical (TAK)
MetricGSKTAK
P/E Ratio (TTM)17.54300.29
P/S Ratio (TTM)3.010.01
P/B Ratio (MRQ)4.021.43
Free Cash Flow Yield (TTM)5.28%1,014.61%