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GSK vs. ONC: GSK vs. BeOne Medicines Stock Comparison

How do GSK (GSK) and BeOne Medicines (ONC) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

GSK (GSK) and BeOne Medicines (ONC) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but GSK is classified in Pharmaceuticals while ONC is classified in Biotechnology.

Both GSK (GSK) and BeOne Medicines (ONC) trade as ADRs — their core financials are comparable, but keep FX, depositary-program fees, and dividend withholding in view for each.

Company profile comparison for GSK (GSK) and BeOne Medicines (ONC)
Profile ItemGSKONC
NameGSK plc ADRBeOne Medicines Ltd. American Depositary Shares
Country/RegionUnited KingdomSwitzerland
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsBiotechnology
GICS Sub-IndustryPharmaceuticalsBiotechnology
Market Capitalization100.88 billion USD46.49 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateMarch 28, 1980February 3, 2016
Security TypeADRADR

Price Performance

Cumulative Growth

GSK
ONC
GSPC
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GSK (GSK) vs. BeOne Medicines (ONC), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for GSK (GSK) and BeOne Medicines (ONC). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for GSK (GSK) and BeOne Medicines (ONC). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for GSK (GSK) and BeOne Medicines (ONC)
MetricGSKONC
Total Return (1Y)13.73%30.59%
Total Return (3Y, Annualized)18.65%30.15%
Total Return (5Y, Annualized)7.97%2.48%

Risk Profile

Drawdown History

GSK
ONC
GSPC
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GSK (GSK) vs. BeOne Medicines (ONC), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for GSK (GSK) and BeOne Medicines (ONC). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for GSK (GSK) and BeOne Medicines (ONC)
MetricGSKONC
Volatility (1Y, Annualized)26.25%35.90%
Beta (5Y)0.310.59
Max Drawdown (5Y)-37.63%-68.89%
Avg. Volume (3M)4.05M405.29K

Risk-Adjusted Performance

Risk-Return Positioning

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GSK and ONC are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for GSK (GSK) and BeOne Medicines (ONC)
MetricGSKONC
Sharpe Ratio (1Y)0.360.73
Sortino Ratio (1Y)0.561.15

Profitability

ROE (TTM)

Both GSK (GSK) at 28.27% and BeOne Medicines (ONC) at 18.40% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.27%

Max
109.18%
GSK
28.27%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

18.40%

Max
109.18%
ONC
18.40%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

For every dollar of sales, both GSK (GSK) at 12.97% and BeOne Medicines (ONC) at 13.86% retain more as net profit than most peers, landing in the top net margin quartile of their industries.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

12.97%

Max
18.05%
GSK
12.97%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.86%

Max
18.05%
ONC
13.86%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both GSK (GSK) at 32.14% and BeOne Medicines (ONC) at 22.15% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.14%

Max
83.12%
GSK
32.14%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

22.15%

Max
83.12%
ONC
22.15%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for GSK (GSK) and BeOne Medicines (ONC)
MetricGSKONC
ROE (TTM)28.27%18.40%
ROA (TTM)9.24%8.42%
Net Margin (TTM)12.97%13.86%
Operating Margin (TTM)32.14%22.15%
Gross Margin (TTM)73.79%89.39%

Growth

Revenue Growth

Both GSK (GSK) at 4.11% and BeOne Medicines (ONC) at 40.23% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: GSK (GSK) reports EPS growth of 123.15%, ranked against its industry; BeOne Medicines (ONC) has no EPS growth figure this period.

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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for GSK (GSK) and BeOne Medicines (ONC)
MetricGSKONC
Revenue Growth (YoY)4.11%40.23%
Revenue Growth (3Y CAGR)3.66%55.69%
EPS Growth (YoY)123.15%--
EPS Growth (3Y CAGR)-27.63%--

Financial Strength

Current Ratio (MRQ)

BeOne Medicines (ONC) at 3.55 keeps current ratio within its industry’s typical mid-range, while GSK (GSK) at 0.86 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for GSK.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.86

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
GSK
0.86
Min
0.10

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.55

Max
25.13
Q3
12.13
Median
5.52
ONC
3.55
Q1
2.47
Min
0.10
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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

BeOne Medicines (ONC) at 0.35 carries an industry-typical debt-to-equity mix, while GSK (GSK) at 1.30 uses more debt funding than most peers.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.30

Max
1.42
GSK
1.30
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.35

Max
1.42
Q3
0.65
ONC
0.35
Median
0.15
Q1
0.02
Min
0.00
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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for GSK (GSK) and BeOne Medicines (ONC)
MetricGSKONC
Current Ratio (MRQ)0.863.55
Debt / Equity (MRQ)1.300.35
Net Debt / EBITDA1.88-2.80

Dividends

Dividend Yield (TTM)

BeOne Medicines (ONC) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile GSK (GSK) reports a yield of 1.57%, ranking against industry peers normally.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.57%

GSK
1.57%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ONC
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

BeOne Medicines (ONC) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile GSK (GSK) reports a payout of 63.33%, ranking against industry peers normally.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

63.33%

GSK
63.33%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ONC
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for GSK (GSK) and BeOne Medicines (ONC)
MetricGSKONC
Dividend Yield (TTM)1.57%0.00%
Dividend Payout Ratio (TTM)63.33%0.00%

Valuation

P/E Ratio (TTM)

GSK (GSK) at 17.54 is near its industry’s usual P/E ratio, while BeOne Medicines (ONC) at 52.17 sits in the richer quartile — ONC needs stronger growth or earnings quality to justify the premium.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.54

Max
85.34
Q3
43.46
Median
26.69
GSK
17.54
Q1
13.30
Min
0.07

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

52.17

Max
85.34
ONC
52.17
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

GSK (GSK) at 3.01 sits in the cheaper P/S ratio quartile while BeOne Medicines (ONC) at 7.04 prices around its industry’s middle — GSK costs less per dollar of sales, though read it alongside growth and margins.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
GSK
3.01
Min
0.01

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.04

Max
58.18
Q3
25.77
Median
7.30
ONC
7.04
Q1
3.01
Min
0.01
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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

GSK (GSK) at 4.02 is valued about in line with its industry on P/B ratio, while BeOne Medicines (ONC) at 7.98 carries an above-peer premium to book — ONC is pricier on assets.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.02

Max
13.53
Q3
6.54
GSK
4.02
Median
3.25
Q1
1.69
Min
-5.59

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.98

Max
13.53
ONC
7.98
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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GSK (GSK) vs. BeOne Medicines (ONC): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for GSK (GSK) and BeOne Medicines (ONC)
MetricGSKONC
P/E Ratio (TTM)17.5452.17
P/S Ratio (TTM)3.017.04
P/B Ratio (MRQ)4.027.98
Free Cash Flow Yield (TTM)5.28%2.21%