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EXEL vs. ISRG: A Head-to-Head Stock Comparison

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Here’s a clear look at EXEL and ISRG, comparing key factors like historical performance, profitability, financial strength, growth, dividend, and valuation.

Company Profile

SymbolEXELISRG
Company NameExelixis, Inc.Intuitive Surgical, Inc.
CountryUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS IndustryBiotechnologyHealth Care Equipment & Supplies
Market Capitalization11.09 billion USD158.13 billion USD
ExchangeNasdaqGSNasdaqGS
Listing DateApril 17, 2000June 16, 2000
Security TypeCommon StockCommon Stock

Historical Performance

This chart compares the performance of EXEL and ISRG by tracking the growth of an initial $10,000 investment in each. Use the tabs to select the desired time period. Data is adjusted for dividends and splits.

EXEL vs. ISRG: Growth of a $10,000 investment over the past one year.

Historical Performance at a Glance

SymbolEXELISRG
5-Day Price Return6.14%0.73%
13-Week Price Return-6.30%-17.70%
26-Week Price Return11.59%-12.14%
52-Week Price Return59.09%-6.67%
Month-to-Date Return10.37%-5.51%
Year-to-Date Return24.02%-14.32%
10-Day Avg. Volume2.68M2.50M
3-Month Avg. Volume3.08M2.04M
3-Month Volatility42.93%24.85%
Beta0.331.61

Profitability

Return on Equity (TTM)

EXEL

27.74%

Biotechnology Industry

Max
97.92%
Q3
11.99%
Median
-19.30%
Q1
-51.29%
Min
-132.03%

In the upper quartile for the Biotechnology industry, EXEL’s Return on Equity of 27.74% signals a highly effective use of shareholder capital to drive profitability compared to most of its peers.

ISRG

15.55%

Health Care Equipment & Supplies Industry

Max
29.93%
Q3
16.99%
Median
9.28%
Q1
5.10%
Min
-12.52%

ISRG’s Return on Equity of 15.55% is on par with the norm for the Health Care Equipment & Supplies industry, indicating its profitability relative to shareholder equity is typical for the sector.

EXEL vs. ISRG: A comparison of their Return on Equity (TTM) against their respective Biotechnology and Health Care Equipment & Supplies industry benchmarks.

Net Profit Margin (TTM)

EXEL

27.01%

Biotechnology Industry

Max
73.34%
Q3
18.98%
Median
-12.96%
Q1
-105.72%
Min
-259.82%

A Net Profit Margin of 27.01% places EXEL in the upper quartile for the Biotechnology industry, signifying strong profitability and more effective cost management than most of its peers.

ISRG

28.51%

Health Care Equipment & Supplies Industry

Max
24.41%
Q3
13.71%
Median
10.08%
Q1
5.96%
Min
-5.58%

ISRG’s Net Profit Margin of 28.51% is exceptionally high, placing it well beyond the typical range for the Health Care Equipment & Supplies industry. This demonstrates outstanding operational efficiency and a strong competitive advantage in converting revenue into profit.

EXEL vs. ISRG: A comparison of their Net Profit Margin (TTM) against their respective Biotechnology and Health Care Equipment & Supplies industry benchmarks.

Operating Profit Margin (TTM)

EXEL

31.38%

Biotechnology Industry

Max
78.85%
Q3
21.90%
Median
-13.30%
Q1
-109.94%
Min
-278.10%

An Operating Profit Margin of 31.38% places EXEL in the upper quartile for the Biotechnology industry. This signals a strong ability to translate revenue into operating profit, outperforming most of its competitors in core business efficiency.

ISRG

28.80%

Health Care Equipment & Supplies Industry

Max
31.09%
Q3
18.11%
Median
15.07%
Q1
8.48%
Min
-0.28%

An Operating Profit Margin of 28.80% places ISRG in the upper quartile for the Health Care Equipment & Supplies industry. This signals a strong ability to translate revenue into operating profit, outperforming most of its competitors in core business efficiency.

EXEL vs. ISRG: A comparison of their Operating Profit Margin (TTM) against their respective Biotechnology and Health Care Equipment & Supplies industry benchmarks.

Profitability at a Glance

SymbolEXELISRG
Return on Equity (TTM)27.74%15.55%
Return on Assets (TTM)21.09%13.75%
Net Profit Margin (TTM)27.01%28.51%
Operating Profit Margin (TTM)31.38%28.80%
Gross Profit Margin (TTM)96.59%66.61%

Financial Strength

Current Ratio (MRQ)

EXEL

3.51

Biotechnology Industry

Max
16.97
Q3
8.39
Median
4.11
Q1
2.64
Min
0.74

EXEL’s Current Ratio of 3.51 aligns with the median group of the Biotechnology industry, indicating that its short-term liquidity is in line with its sector peers.

ISRG

5.64

Health Care Equipment & Supplies Industry

Max
5.19
Q3
3.00
Median
2.13
Q1
1.44
Min
0.86

ISRG’s Current Ratio of 5.64 is exceptionally high, placing it well outside the typical range for the Health Care Equipment & Supplies industry. This indicates a very strong liquidity position, though such a high ratio may also suggest that the company is not using its assets efficiently to generate profits.

EXEL vs. ISRG: A comparison of their Current Ratio (MRQ) against their respective Biotechnology and Health Care Equipment & Supplies industry benchmarks.

Debt-to-Equity Ratio (MRQ)

EXEL

0.00

Biotechnology Industry

Max
1.92
Q3
0.79
Median
0.12
Q1
0.00
Min
0.00

EXEL’s Debt-to-Equity Ratio of 0.00 is typical for the Biotechnology industry, indicating its use of leverage is in line with the sector norm. This suggests a balanced approach to its capital structure.

ISRG

0.00

Health Care Equipment & Supplies Industry

Max
1.61
Q3
0.76
Median
0.45
Q1
0.14
Min
0.00

Falling into the lower quartile for the Health Care Equipment & Supplies industry, ISRG’s Debt-to-Equity Ratio of 0.00 points to a conservative financing strategy. This results in lower financial risk but potentially limits strategic investments compared to more leveraged competitors.

EXEL vs. ISRG: A comparison of their Debt-to-Equity Ratio (MRQ) against their respective Biotechnology and Health Care Equipment & Supplies industry benchmarks.

Interest Coverage Ratio (TTM)

EXEL

42.74

Biotechnology Industry

Max
72.37
Q3
1.03
Median
-9.59
Q1
-65.05
Min
-163.11

EXEL’s Interest Coverage Ratio of 42.74 is in the upper quartile for the Biotechnology industry, signifying a strong and healthy capacity to meet its interest payments from operating profits.

ISRG

--

Health Care Equipment & Supplies Industry

Max
56.35
Q3
25.56
Median
9.60
Q1
3.78
Min
-26.49

Interest Coverage Ratio data for ISRG is currently unavailable.

EXEL vs. ISRG: A comparison of their Interest Coverage Ratio (TTM) against their respective Biotechnology and Health Care Equipment & Supplies industry benchmarks.

Financial Strength at a Glance

SymbolEXELISRG
Current Ratio (MRQ)3.515.64
Quick Ratio (MRQ)3.224.89
Debt-to-Equity Ratio (MRQ)0.000.00
Interest Coverage Ratio (TTM)42.74--

Growth

Revenue Growth

EXEL vs. ISRG: A side-by-side comparison of their Revenue Growth for the MRQ (YoY), TTM (YoY), 3-Year CAGR, and 5-Year CAGR periods.

EPS Growth

EXEL vs. ISRG: A side-by-side comparison of their EPS Growth for the MRQ (YoY), TTM (YoY), 3-Year CAGR, and 5-Year CAGR periods.

Dividend

Dividend Yield (TTM)

EXEL

0.00%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

EXEL currently does not pay a dividend, resulting in a yield of 0%. This is a common strategy for growth-focused companies that prioritize reinvesting earnings, though it may be less typical in mature, income-oriented sectors.

ISRG

0.00%

Health Care Equipment & Supplies Industry

Max
4.15%
Q3
1.76%
Median
0.79%
Q1
0.00%
Min
0.00%

ISRG currently does not pay a dividend, resulting in a yield of 0%. This is a common strategy for growth-focused companies that prioritize reinvesting earnings, though it may be less typical in mature, income-oriented sectors.

EXEL vs. ISRG: A comparison of their Dividend Yield (TTM) against their respective Biotechnology and Health Care Equipment & Supplies industry benchmarks.

Dividend Payout Ratio (TTM)

EXEL

0.00%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

EXEL has a Dividend Payout Ratio of 0%, indicating it does not currently pay a dividend. This is a common strategy for growth-oriented companies that reinvest all profits back into the business.

ISRG

0.00%

Health Care Equipment & Supplies Industry

Max
160.00%
Q3
66.60%
Median
27.49%
Q1
0.00%
Min
0.00%

ISRG has a Dividend Payout Ratio of 0%, indicating it does not currently pay a dividend. This is a common strategy for growth-oriented companies that reinvest all profits back into the business.

EXEL vs. ISRG: A comparison of their Dividend Payout Ratio (TTM) against their respective Biotechnology and Health Care Equipment & Supplies industry benchmarks.

Dividend at a Glance

SymbolEXELISRG
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

Price-to-Earnings Ratio (TTM)

EXEL

18.37

Biotechnology Industry

Max
40.44
Q3
39.37
Median
22.12
Q1
15.76
Min
3.48

EXEL’s P/E Ratio of 18.37 is within the middle range for the Biotechnology industry. This suggests its valuation is in line with the sector average, representing neither a significant premium nor a discount compared to its peers.

ISRG

61.32

Health Care Equipment & Supplies Industry

Max
67.29
Q3
47.01
Median
30.94
Q1
23.91
Min
10.79

A P/E Ratio of 61.32 places ISRG in the upper quartile for the Health Care Equipment & Supplies industry. This high valuation relative to peers suggests the market holds elevated expectations for the company’s future growth.

EXEL vs. ISRG: A comparison of their Price-to-Earnings Ratio (TTM) against their respective Biotechnology and Health Care Equipment & Supplies industry benchmarks.

Price-to-Sales Ratio (TTM)

EXEL

4.96

Biotechnology Industry

Max
92.67
Q3
41.36
Median
8.45
Q1
4.46
Min
0.97

EXEL’s P/S Ratio of 4.96 aligns with the market consensus for the Biotechnology industry. This suggests its valuation, based on sales, is seen as standard and is on par with its competitors.

ISRG

17.49

Health Care Equipment & Supplies Industry

Max
9.49
Q3
5.41
Median
2.86
Q1
2.07
Min
0.74

With a P/S Ratio of 17.49, ISRG trades at a valuation that eclipses even the highest in the Health Care Equipment & Supplies industry. This implies the market has priced in exceptionally optimistic scenarios for future revenue growth, posing considerable valuation risk.

EXEL vs. ISRG: A comparison of their Price-to-Sales Ratio (TTM) against their respective Biotechnology and Health Care Equipment & Supplies industry benchmarks.

Price-to-Book Ratio (MRQ)

EXEL

6.19

Biotechnology Industry

Max
22.72
Q3
10.68
Median
4.55
Q1
2.44
Min
0.59

EXEL’s P/B Ratio of 6.19 is within the conventional range for the Biotechnology industry. This shows a balanced market view, where the stock’s price is neither at a significant premium nor a discount to the book value of its peers.

ISRG

10.85

Health Care Equipment & Supplies Industry

Max
10.85
Q3
6.56
Median
3.53
Q1
2.36
Min
0.71

ISRG’s P/B Ratio of 10.85 is in the upper tier for the Health Care Equipment & Supplies industry. This indicates that investors are paying a premium relative to the company’s net assets, a valuation that hinges on its ability to generate superior profits.

EXEL vs. ISRG: A comparison of their Price-to-Book Ratio (MRQ) against their respective Biotechnology and Health Care Equipment & Supplies industry benchmarks.

Valuation at a Glance

SymbolEXELISRG
Price-to-Earnings Ratio (TTM)18.3761.32
Price-to-Sales Ratio (TTM)4.9617.49
Price-to-Book Ratio (MRQ)6.1910.85
Price-to-Free Cash Flow Ratio (TTM)14.6780.18