DHR vs. TAK: Danaher vs. Takeda Pharmaceutical Stock Comparison
How do Danaher (DHR) and Takeda Pharmaceutical (TAK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Danaher (DHR) and Takeda Pharmaceutical (TAK) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but DHR is classified in Life Sciences Tools & Services while TAK is classified in Pharmaceuticals.
Danaher (DHR) trades as ordinary local shares, while Takeda Pharmaceutical (TAK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.
| Profile Item | DHR | TAK |
|---|---|---|
| Name | Danaher Corp. | Takeda Pharmaceutical Co Ltd ADR |
| Country/Region | United States | Japan |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Life Sciences Tools & Services | Pharmaceuticals |
| GICS Sub-Industry | Life Sciences Tools & Services | Pharmaceuticals |
| Market Capitalization | 161.86 billion USD | 67.16 billion USD |
| Currency | USD | USD |
| Exchange | NYSE | NYSE |
| Listing Date | December 29, 1978 | January 5, 2010 |
| Security Type | Common Stock | ADR |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | DHR | TAK |
|---|---|---|
| Total Return (1Y) | 11.88% | 54.54% |
| Total Return (3Y, Annualized) | 6.67% | 18.39% |
| Total Return (5Y, Annualized) | -2.05% | 9.29% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Danaher (DHR) has a non-negative beta of 0.76.
| Metric | DHR | TAK |
|---|---|---|
| Volatility (1Y, Annualized) | 30.61% | 21.45% |
| Beta (5Y) | 0.76 | -0.01 |
| Max Drawdown (5Y) | -43.31% | -24.83% |
| Avg. Volume (3M) | 3.94M | 2.61M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | DHR | TAK |
|---|---|---|
| Sharpe Ratio (1Y) | 0.25 | 2.34 |
| Sortino Ratio (1Y) | 0.35 | 3.88 |
Profitability
ROE (TTM)
Danaher (DHR) at 8.19% sits in the top ROE quartile, while Takeda Pharmaceutical (TAK) at 0.56% is closer to the peer norm — stronger capital efficiency for DHR.
DHR
Pharmaceuticals, Biotechnology & Life Sciences industry group
8.19%
- Max
- 109.18%
- DHR
- 8.19%
- Q3
- 6.23%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.56%
- Max
- 109.18%
- Q3
- 6.23%
- TAK
- 0.56%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
Net Margin (TTM)
Danaher (DHR) at 16.91% retains a top-quartile share of revenue as profit, ahead of Takeda Pharmaceutical (TAK) at 0.87%, which keeps about the industry-typical share.
DHR
Pharmaceuticals, Biotechnology & Life Sciences industry group
16.91%
- Max
- 18.05%
- DHR
- 16.91%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.87%
- Max
- 18.05%
- Q3
- 4.78%
- TAK
- 0.87%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
Operating Margin (TTM)
Both Danaher (DHR) at 21.13% and Takeda Pharmaceutical (TAK) at 24.55% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.
DHR
Pharmaceuticals, Biotechnology & Life Sciences industry group
21.13%
- Max
- 83.12%
- DHR
- 21.13%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
24.55%
- Max
- 83.12%
- TAK
- 24.55%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
Profitability Metrics
| Metric | DHR | TAK |
|---|---|---|
| ROE (TTM) | 8.19% | 0.56% |
| ROA (TTM) | 4.06% | 3.27% |
| Net Margin (TTM) | 16.91% | 0.87% |
| Operating Margin (TTM) | 21.13% | 24.55% |
| Gross Margin (TTM) | 59.36% | 64.77% |
Growth
Revenue Growth
Danaher (DHR) at 2.90% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.
EPS Growth
Takeda Pharmaceutical (TAK) at 77.96% sits in the top EPS growth quartile, while Danaher (DHR) at -4.54% is closer to the peer norm — faster per-share earnings growth for TAK.
Growth Metrics
| Metric | DHR | TAK |
|---|---|---|
| Revenue Growth (YoY) | 2.90% | -1.66% |
| Revenue Growth (3Y CAGR) | -2.67% | 3.81% |
| EPS Growth (YoY) | -4.54% | 77.96% |
| EPS Growth (3Y CAGR) | -19.44% | -16.01% |
Financial Strength
Current Ratio (MRQ)
Both Danaher (DHR) at 1.63 and Takeda Pharmaceutical (TAK) at 1.15 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.
DHR
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.63
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- DHR
- 1.63
- Min
- 0.10
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.15
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- TAK
- 1.15
- Min
- 0.10
Debt / Equity (MRQ)
Danaher (DHR) at 0.52 carries an industry-typical debt-to-equity mix, while Takeda Pharmaceutical (TAK) at 0.72 uses more debt funding than most peers.
DHR
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.52
- Max
- 1.42
- Q3
- 0.65
- DHR
- 0.52
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.72
- Max
- 1.42
- TAK
- 0.72
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
Financial Strength Metrics
| Metric | DHR | TAK |
|---|---|---|
| Current Ratio (MRQ) | 1.63 | 1.15 |
| Debt / Equity (MRQ) | 0.52 | 0.72 |
| Net Debt / EBITDA | 2.68 | 3.61 |
Dividends
Dividend Yield (TTM)
Both Danaher (DHR) at 0.67% and Takeda Pharmaceutical (TAK) at 953.28% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.
DHR
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.67%
- DHR
- 0.67%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
953.28%
- TAK
- 953.28%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings and sustainability needs extra context. Meanwhile Danaher (DHR) reports 25.17%, ranking against industry peers normally.
DHR
Pharmaceuticals, Biotechnology & Life Sciences industry group
25.17%
- DHR
- 25.17%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
426.53%
- TAK
- 426.53%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | DHR | TAK |
|---|---|---|
| Dividend Yield (TTM) | 0.67% | 953.28% |
| Dividend Payout Ratio (TTM) | 25.17% | 426.53% |
Valuation
P/E Ratio (TTM)
Danaher (DHR) at 38.12 is near its industry’s usual P/E ratio, while Takeda Pharmaceutical (TAK) at 300.29 sits above its peer range — an unusually expensive price for TAK’s trailing earnings.
DHR
Pharmaceuticals, Biotechnology & Life Sciences industry group
38.12
- Max
- 85.34
- Q3
- 43.46
- DHR
- 38.12
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
300.29
- TAK
- 300.29
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
P/S Ratio (TTM)
Takeda Pharmaceutical (TAK) at 0.01 sits in the cheaper P/S ratio quartile while Danaher (DHR) at 6.32 prices around its industry’s middle — TAK costs less per dollar of sales, though read it alongside growth and margins.
DHR
Pharmaceuticals, Biotechnology & Life Sciences industry group
6.32
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- DHR
- 6.32
- Q1
- 3.01
- Min
- 0.01
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.01
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- Q1
- 3.01
- TAK
- 0.01
- Min
- 0.01
P/B Ratio (MRQ)
Takeda Pharmaceutical (TAK) at 1.43 sits in the lower P/B ratio quartile against book while Danaher (DHR) at 3.02 is valued near its industry’s middle — TAK is cheaper on assets, though weigh it against ROE and asset quality.
DHR
Pharmaceuticals, Biotechnology & Life Sciences industry group
3.02
- Max
- 13.53
- Q3
- 6.54
- Median
- 3.25
- DHR
- 3.02
- Q1
- 1.69
- Min
- -5.59
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.43
- Max
- 13.53
- Q3
- 6.54
- Median
- 3.25
- Q1
- 1.69
- TAK
- 1.43
- Min
- -5.59
Valuation Metrics
| Metric | DHR | TAK |
|---|---|---|
| P/E Ratio (TTM) | 38.12 | 300.29 |
| P/S Ratio (TTM) | 6.32 | 0.01 |
| P/B Ratio (MRQ) | 3.02 | 1.43 |
| Free Cash Flow Yield (TTM) | 2.93% | 1,014.61% |