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BMRN vs. TAK: BioMarin Pharmaceutical vs. Takeda Pharmaceutical Stock Comparison

How do BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but BMRN is classified in Biotechnology while TAK is classified in Pharmaceuticals.

BioMarin Pharmaceutical (BMRN) trades as ordinary local shares, while Takeda Pharmaceutical (TAK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK)
Profile ItemBMRNTAK
NameBioMarin Pharmaceutical Inc.Takeda Pharmaceutical Co Ltd ADR
Country/RegionUnited StatesJapan
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization10.85 billion USD67.16 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateJuly 26, 1999January 5, 2010
Security TypeCommon StockADR

Price Performance

Cumulative Growth

BMRN
TAK
GSPC
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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK)
MetricBMRNTAK
Total Return (1Y)8.82%54.54%
Total Return (3Y, Annualized)-12.54%18.39%
Total Return (5Y, Annualized)-7.51%9.29%

Risk Profile

Drawdown History

BMRN
TAK
GSPC
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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. BioMarin Pharmaceutical (BMRN) has a non-negative beta of 0.24.

Risk profile metrics for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK)
MetricBMRNTAK
Volatility (1Y, Annualized)35.50%21.45%
Beta (5Y)0.24-0.01
Max Drawdown (5Y)-57.64%-24.83%
Avg. Volume (3M)2.28M2.61M

Risk-Adjusted Performance

Risk-Return Positioning

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BMRN and TAK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK)
MetricBMRNTAK
Sharpe Ratio (1Y)0.132.34
Sortino Ratio (1Y)0.233.88

Profitability

ROE (TTM)

BioMarin Pharmaceutical (BMRN) reports a negative ROE of -0.31%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Takeda Pharmaceutical (TAK) reports 0.56%, ranking against industry peers normally.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.31%

Max
109.18%
Q3
6.23%
BMRN
-0.31%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.56%

Max
109.18%
Q3
6.23%
TAK
0.56%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

BioMarin Pharmaceutical (BMRN) reports a negative net margin of -0.52%, usually indicating a net loss over the period. Meanwhile Takeda Pharmaceutical (TAK) reports 0.87%, ranking against industry peers normally.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.52%

Max
18.05%
Q3
4.78%
Median
0.00%
BMRN
-0.52%
Q1
-4.14%
Min
-17.05%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87%

Max
18.05%
Q3
4.78%
TAK
0.87%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both BioMarin Pharmaceutical (BMRN) at 26.58% and Takeda Pharmaceutical (TAK) at 24.55% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.58%

Max
83.12%
BMRN
26.58%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.55%

Max
83.12%
TAK
24.55%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK)
MetricBMRNTAK
ROE (TTM)-0.31%0.56%
ROA (TTM)3.89%3.27%
Net Margin (TTM)-0.52%0.87%
Operating Margin (TTM)26.58%24.55%
Gross Margin (TTM)53.21%64.77%

Growth

Revenue Growth

BioMarin Pharmaceutical (BMRN) at 12.87% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): A comparison of their Revenue Growth across different time periods.

EPS Growth

Takeda Pharmaceutical (TAK) at 77.96% sits in the top EPS growth quartile, while BioMarin Pharmaceutical (BMRN) at -18.55% is closer to the peer norm — faster per-share earnings growth for TAK.

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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK)
MetricBMRNTAK
Revenue Growth (YoY)12.87%-1.66%
Revenue Growth (3Y CAGR)15.40%3.81%
EPS Growth (YoY)-18.55%77.96%
EPS Growth (3Y CAGR)33.89%-16.01%

Financial Strength

Current Ratio (MRQ)

Both BioMarin Pharmaceutical (BMRN) at 2.44 and Takeda Pharmaceutical (TAK) at 1.15 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.44

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
BMRN
2.44
Min
0.10

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.15

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TAK
1.15
Min
0.10
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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both BioMarin Pharmaceutical (BMRN) at 0.67 and Takeda Pharmaceutical (TAK) at 0.72 lean more heavily on debt funding than most peers, landing in the higher-leverage quartile of their industries.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.67

Max
1.42
BMRN
0.67
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.72

Max
1.42
TAK
0.72
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK)
MetricBMRNTAK
Current Ratio (MRQ)2.441.15
Debt / Equity (MRQ)0.670.72
Net Debt / EBITDA4.043.61

Dividends

Dividend Yield (TTM)

BioMarin Pharmaceutical (BMRN) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Takeda Pharmaceutical (TAK) reports a yield of 953.28%, ranking against industry peers normally.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BMRN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

953.28%

TAK
953.28%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings; BioMarin Pharmaceutical (BMRN) pays no dividend (payout 0.00%).

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BMRN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

426.53%

TAK
426.53%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK)
MetricBMRNTAK
Dividend Yield (TTM)0.00%953.28%
Dividend Payout Ratio (TTM)0.00%426.53%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Takeda Pharmaceutical (TAK) trades at 300.29 times trailing earnings, ranked against its peers, while BioMarin Pharmaceutical (BMRN) has no P/E ratio this period.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
BMRN
--

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

300.29

TAK
300.29
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): BMRN does not report P/E ratio, so it has no value marker; TAK is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

Both BioMarin Pharmaceutical (BMRN) at 2.97 and Takeda Pharmaceutical (TAK) at 0.01 fetch a relatively low price per dollar of sales, landing in the cheaper P/S ratio quartile of their industries.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.97

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
BMRN
2.97
Min
0.01

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
TAK
0.01
Min
0.01
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BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Takeda Pharmaceutical (TAK) at 1.43 sits in the lower P/B ratio quartile against book while BioMarin Pharmaceutical (BMRN) at 1.73 is valued near its industry’s middle — TAK is cheaper on assets, though weigh it against ROE and asset quality.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.73

Max
13.53
Q3
6.54
Median
3.25
BMRN
1.73
Q1
1.69
Min
-5.59

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.43

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
TAK
1.43
Min
-5.59
Loading chart…
BioMarin Pharmaceutical (BMRN) vs. Takeda Pharmaceutical (TAK): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for BioMarin Pharmaceutical (BMRN) and Takeda Pharmaceutical (TAK)
MetricBMRNTAK
P/E Ratio (TTM)--300.29
P/S Ratio (TTM)2.970.01
P/B Ratio (MRQ)1.731.43
Free Cash Flow Yield (TTM)-0.15%1,014.61%