AstraZeneca (AZN) vs. Merck (MRK)
This page compares AstraZeneca (AZN) with Merck (MRK) using historical performance, profitability, financial strength, growth, dividend, and valuation metrics.
Company Profile
AstraZeneca (AZN) and Merck (MRK) are both classified in the Pharmaceuticals sub-industry within the broader Pharmaceuticals industry, placing them in the closest GICS peer bucket.
| Symbol | AZN | MRK |
|---|---|---|
| Company Name | AstraZeneca PLC | Merck & Co., Inc. |
| Country/Region | United Kingdom | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Pharmaceuticals | Pharmaceuticals |
| GICS Sub-Industry | Pharmaceuticals | Pharmaceuticals |
| Market Capitalization | 294.27 billion USD | 286.20 billion USD |
| Currency | USD | USD |
| Exchange | NYSE | NYSE |
| Listing Date | May 12, 1993 | January 2, 1962 |
| Security Type | Common Stock | Common Stock |
Historical Performance
AstraZeneca (AZN) has an aggressive beta of 1.31, indicating higher sensitivity to broad-market moves, while Merck (MRK) is defensive at 0.20 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.
Historical Performance at a Glance
| Symbol | AZN | MRK |
|---|---|---|
| 5-Day Price Return | 1.53% | 4.04% |
| 13-Week Price Return | -7.98% | -4.91% |
| 26-Week Price Return | 3.20% | 24.70% |
| 52-Week Price Return | 33.67% | 50.53% |
| Month-to-Date Return | 0.01% | 6.14% |
| Year-to-Date Return | 1.16% | 10.09% |
| 10-Day Avg. Volume | 1.13M | 7.82M |
| 3-Month Avg. Volume | 1.35M | 10.62M |
| 3-Month Volatility | 24.15% | 24.25% |
| Beta | 1.31 | 0.20 |
Profitability
Return on Equity (TTM)
Both AstraZeneca (AZN) at 22.27% and Merck (MRK) at 17.93% rank in the top quartile for Return on Equity (TTM) among industry peers, indicating strong returns on shareholders’ equity.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
22.27%
- Max
- 101.31%
- Q3
- 9.45%
- Median
- -24.29%
- Q1
- -57.59%
- Min
- -152.10%
MRK
Pharmaceuticals, Biotechnology & Life Sciences industry group
17.93%
- Max
- 101.31%
- Q3
- 9.45%
- Median
- -24.29%
- Q1
- -57.59%
- Min
- -152.10%
Net Profit Margin (TTM)
AstraZeneca (AZN) at 17.19% ranks in the top quartile for Net Profit Margin (TTM), ahead of Merck (MRK) at 13.59%, which sits closer to the industry mid-range.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
17.19%
- Max
- 90.67%
- Q3
- 13.59%
- Median
- -9.02%
- Q1
- -156.67%
- Min
- -407.00%
MRK
Pharmaceuticals, Biotechnology & Life Sciences industry group
13.59%
- Max
- 90.67%
- Q3
- 13.59%
- Median
- -9.02%
- Q1
- -156.67%
- Min
- -407.00%
Operating Profit Margin (TTM)
Both AstraZeneca (AZN) at 23.69% and Merck (MRK) at 18.18% rank in the top quartile for Operating Profit Margin (TTM) among industry peers, indicating both companies convert revenue into operating income more strongly than typical competitors.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
23.69%
- Max
- 65.08%
- Q3
- 16.47%
- Median
- -9.50%
- Q1
- -194.89%
- Min
- -449.94%
MRK
Pharmaceuticals, Biotechnology & Life Sciences industry group
18.18%
- Max
- 65.08%
- Q3
- 16.47%
- Median
- -9.50%
- Q1
- -194.89%
- Min
- -449.94%
Profitability at a Glance
| Symbol | AZN | MRK |
|---|---|---|
| Return on Equity (TTM) | 22.27% | 17.93% |
| Return on Assets (TTM) | 9.13% | 6.97% |
| Net Profit Margin (TTM) | 17.19% | 13.59% |
| Operating Profit Margin (TTM) | 23.69% | 18.18% |
| Gross Profit Margin (TTM) | 81.42% | 78.07% |
Financial Strength
Current Ratio (MRQ)
Both AstraZeneca (AZN) at 0.91 and Merck (MRK) at 1.30 run Current Ratio (MRQ) in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.91
- Max
- 19.59
- Q3
- 9.51
- Median
- 4.07
- Q1
- 2.07
- Min
- 0.67
MRK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.30
- Max
- 19.59
- Q3
- 9.51
- Median
- 4.07
- Q1
- 2.07
- Min
- 0.67
Debt-to-Equity Ratio (MRQ)
AstraZeneca (AZN) at 0.72 carries Debt-to-Equity Ratio (MRQ) around its industry mid-range, while Merck (MRK) at 1.07 sits in the higher-leverage quartile.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.72
- Max
- 2.26
- Q3
- 1.00
- Median
- 0.19
- Q1
- 0.00
- Min
- 0.00
MRK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.07
- Max
- 2.26
- Q3
- 1.00
- Median
- 0.19
- Q1
- 0.00
- Min
- 0.00
Interest Coverage Ratio (TTM)
Both AstraZeneca (AZN) at 12.68 and Merck (MRK) at 22.74 rank in the top quartile for Interest Coverage Ratio (TTM) among industry peers, indicating ample headroom to cover interest payments from operating income or EBIT.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
12.68
- Max
- 72.37
- Q3
- 4.99
- Median
- -4.89
- Q1
- -43.93
- Min
- -104.22
MRK
Pharmaceuticals, Biotechnology & Life Sciences industry group
22.74
- Max
- 72.37
- Q3
- 4.99
- Median
- -4.89
- Q1
- -43.93
- Min
- -104.22
Financial Strength at a Glance
| Symbol | AZN | MRK |
|---|---|---|
| Current Ratio (MRQ) | 0.91 | 1.30 |
| Quick Ratio (MRQ) | 0.71 | 1.06 |
| Debt-to-Equity Ratio (MRQ) | 0.72 | 1.07 |
| Interest Coverage Ratio (TTM) | 12.68 | 22.74 |
Growth
Revenue Growth
Revenue Growth at a Glance
| Symbol | AZN | MRK |
|---|---|---|
| Revenue Growth (MRQ vs Prior YoY) | 12.51% | 4.87% |
| Revenue Growth (TTM vs Prior YoY) | 9.93% | 2.89% |
| 3-Year Revenue CAGR | 9.82% | 3.12% |
| 5-Year Revenue CAGR | 17.15% | 9.38% |
EPS Growth
EPS Growth at a Glance
| Symbol | AZN | MRK |
|---|---|---|
| EPS Growth (MRQ vs Prior YoY) | 5.63% | -- |
| EPS Growth (TTM vs Prior YoY) | 33.71% | -48.26% |
| 3-Year EPS CAGR | 45.90% | 8.43% |
| 5-Year EPS CAGR | 21.88% | 21.23% |
Dividend
Dividend Yield (TTM)
Both AstraZeneca (AZN) at 1.69% and Merck (MRK) at 2.91% report Dividend Yield (TTM) near their industry mid-ranges, so neither company stands out strongly from peers on cash yield relative to share price.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.69%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
MRK
Pharmaceuticals, Biotechnology & Life Sciences industry group
2.91%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Both AstraZeneca (AZN) at 47.27% and Merck (MRK) at 44.79% post Dividend Payout Ratio (TTM) outside their industries’ typical mid-range — either leaning toward more retention or more distribution than the industry median.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
47.27%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
MRK
Pharmaceuticals, Biotechnology & Life Sciences industry group
44.79%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend at a Glance
| Symbol | AZN | MRK |
|---|---|---|
| Dividend Yield (TTM) | 1.69% | 2.91% |
| Dividend Payout Ratio (TTM) | 47.27% | 44.79% |
Valuation
Price-to-Earnings Ratio (TTM)
Both AstraZeneca (AZN) at 27.96 and Merck (MRK) at 31.61 post Price-to-Earnings Ratio (TTM) near the typical industry midpoint — neither company stands out strongly from peers on trailing earnings multiple.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
27.96
- Max
- 68.36
- Q3
- 38.86
- Median
- 25.36
- Q1
- 17.81
- Min
- 4.59
MRK
Pharmaceuticals, Biotechnology & Life Sciences industry group
31.61
- Max
- 68.36
- Q3
- 38.86
- Median
- 25.36
- Q1
- 17.81
- Min
- 4.59
Price-to-Sales Ratio (TTM)
Both AstraZeneca (AZN) at 4.81 and Merck (MRK) at 4.30 post Price-to-Sales Ratio (TTM) near the typical industry midpoint — neither company stands out strongly from peers on trailing revenue multiple.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
4.81
- Max
- 45.85
- Q3
- 22.84
- Median
- 6.16
- Q1
- 3.49
- Min
- 0.19
MRK
Pharmaceuticals, Biotechnology & Life Sciences industry group
4.30
- Max
- 45.85
- Q3
- 22.84
- Median
- 6.16
- Q1
- 3.49
- Min
- 0.19
Price-to-Book Ratio (MRQ)
Both AstraZeneca (AZN) at 6.46 and Merck (MRK) at 6.48 post Price-to-Book Ratio (MRQ) near the typical industry midpoint — neither company stands out strongly from peers on book-value multiple.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
6.46
- Max
- 19.86
- Q3
- 9.76
- Median
- 4.52
- Q1
- 2.54
- Min
- 0.54
MRK
Pharmaceuticals, Biotechnology & Life Sciences industry group
6.48
- Max
- 19.86
- Q3
- 9.76
- Median
- 4.52
- Q1
- 2.54
- Min
- 0.54
Valuation at a Glance
| Symbol | AZN | MRK |
|---|---|---|
| Price-to-Earnings Ratio (TTM) | 27.96 | 31.61 |
| Price-to-Sales Ratio (TTM) | 4.81 | 4.30 |
| Price-to-Book Ratio (MRQ) | 6.46 | 6.48 |
| Price-to-Free Cash Flow Ratio (TTM) | 37.49 | 20.01 |