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AstraZeneca (AZN) vs. GSK (GSK)

This page compares AstraZeneca (AZN) with GSK (GSK) using performance and risk, profitability, financial strength, growth, dividends, and valuation metrics.

Company Profile

AstraZeneca (AZN) and GSK (GSK) are both classified in the Pharmaceuticals sub-industry within the broader Pharmaceuticals industry, placing them in the closest GICS peer bucket.

Both AstraZeneca (AZN, ADR) and GSK (GSK, ADR) trade as depositary receipts or similar foreign-share lines; core company financials may still be comparable, but trading line, FX, program fees, dividend withholding, and home-market rules are worth keeping in view.

SymbolAZNGSK
NameAstraZeneca PLC American Depositary SharesGSK plc Sponsored ADR
Country/RegionUnited KingdomUnited Kingdom
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsPharmaceuticals
GICS Sub-IndustryPharmaceuticalsPharmaceuticals
Market Capitalization287.95 billion USD101.38 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateMay 12, 1993March 28, 1980
Security TypeADRADR

Valuation

Price-to-Earnings Ratio (TTM)

GSK (GSK) at 13.27 trades in the lower-multiple quartile for Price-to-Earnings Ratio (TTM), while AstraZeneca (AZN) at 27.92 sits around the industry midpoint — GSK has a lower trailing earnings multiple relative to peers, though the gap should be read alongside growth and earnings quality.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

27.92

Max
77.51
Q3
42.45
Median
25.47
Q1
14.64
Min
1.58

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.27

Max
77.51
Q3
42.45
Median
25.47
Q1
14.64
Min
1.58
AstraZeneca (AZN) vs. GSK (GSK): A comparison of their Price-to-Earnings Ratio (TTM) against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Price-to-Sales Ratio (TTM)

GSK (GSK) at 3.09 sits in the cheaper Price-to-Sales Ratio (TTM) quartile while AstraZeneca (AZN) at 4.76 prices around its industry’s middle — GSK costs less per dollar of sales, though read it alongside growth and margins.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.76

Max
60.01
Q3
26.95
Median
6.83
Q1
3.43
Min
0.01

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.09

Max
60.01
Q3
26.95
Median
6.83
Q1
3.43
Min
0.01
AstraZeneca (AZN) vs. GSK (GSK): A comparison of their Price-to-Sales Ratio (TTM) against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Price-to-Book Ratio (MRQ)

On Price-to-Book Ratio (MRQ), both AstraZeneca (AZN) at 6.08 and GSK (GSK) at 4.23 are valued close to their industries’ norm against book — neither stands out from peers.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.08

Max
12.80
Q3
6.35
Median
3.45
Q1
1.69
Min
-4.09

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.23

Max
12.80
Q3
6.35
Median
3.45
Q1
1.69
Min
-4.09
AstraZeneca (AZN) vs. GSK (GSK): A comparison of their Price-to-Book Ratio (MRQ) against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation at a Glance

SymbolAZNGSK
Price-to-Earnings Ratio (TTM)27.9213.27
Price-to-Sales Ratio (TTM)4.763.09
Price-to-Book Ratio (MRQ)6.084.23
Free Cash Flow Yield2.28%2.98%

Profitability

Return on Equity (TTM)

Both AstraZeneca (AZN) at 23.48% and GSK (GSK) at 40.91% rank in the top quartile for Return on Equity (TTM) among industry peers, indicating strong returns on shareholders’ equity.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.48%

Max
94.73%
Q3
2.50%
Median
-32.62%
Q1
-61.80%
Min
-157.07%

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

40.91%

Max
94.73%
Q3
2.50%
Median
-32.62%
Q1
-61.80%
Min
-157.07%
AstraZeneca (AZN) vs. GSK (GSK): A comparison of their Return on Equity (TTM) against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Profit Margin (TTM)

Both AstraZeneca (AZN) at 17.19% and GSK (GSK) at 17.78% keep an unusually large share of revenue as bottom-line profit — each Net Profit Margin (TTM) clears its industry’s benchmark range.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.19%

Max
11.21%
Q3
3.34%
Median
0.00%
Q1
-2.04%
Min
-9.05%

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.78%

Max
11.21%
Q3
3.34%
Median
0.00%
Q1
-2.04%
Min
-9.05%
AstraZeneca (AZN) vs. GSK (GSK): A comparison of their Net Profit Margin (TTM) against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Profit Margin (TTM)

Both AstraZeneca (AZN) at 27.94% and GSK (GSK) at 36.28% squeeze more operating profit from each sales dollar than most peers, ranking in the top Operating Profit Margin (TTM) quartile of their industries.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

27.94%

Max
100.30%
Q3
3.47%
Median
0.00%
Q1
-138.44%
Min
-337.81%

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

36.28%

Max
100.30%
Q3
3.47%
Median
0.00%
Q1
-138.44%
Min
-337.81%
AstraZeneca (AZN) vs. GSK (GSK): A comparison of their Operating Profit Margin (TTM) against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability at a Glance

SymbolAZNGSK
Return on Equity (TTM)23.48%40.91%
Return on Assets (TTM)8.49%10.02%
Net Profit Margin (TTM)17.19%17.78%
Operating Profit Margin (TTM)27.94%36.28%
Gross Profit Margin (TTM)81.51%72.87%

Growth

Revenue Growth

AstraZeneca (AZN) vs. GSK (GSK): A comparison of their Revenue Growth across different time periods.

Revenue Growth at a Glance

SymbolAZNGSK
1-Year Revenue Growth8.63%4.11%
3-Year Revenue CAGR9.82%3.66%

EPS Growth

AstraZeneca (AZN) vs. GSK (GSK): A comparison of their EPS Growth across different time periods.

EPS Growth at a Glance

SymbolAZNGSK
1-Year EPS Growth45.33%123.15%
3-Year EPS CAGR45.80%-27.63%

Financial Strength

Current Ratio (MRQ)

Both AstraZeneca (AZN) at 0.91 and GSK (GSK) at 0.79 run Current Ratio (MRQ) in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.91

Max
24.81
Q3
11.93
Median
5.83
Q1
2.73
Min
0.23

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.79

Max
24.81
Q3
11.93
Median
5.83
Q1
2.73
Min
0.23
AstraZeneca (AZN) vs. GSK (GSK): A comparison of their Current Ratio (MRQ) against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt-to-Equity Ratio (MRQ)

Both AstraZeneca (AZN) at 0.72 and GSK (GSK) at 1.10 run Debt-to-Equity Ratio (MRQ) in the higher-leverage quartile of industry peers, indicating more debt relative to equity than typical competitors.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.72

Max
1.60
Q3
0.67
Median
0.15
Q1
0.02
Min
0.00

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.10

Max
1.60
Q3
0.67
Median
0.15
Q1
0.02
Min
0.00
AstraZeneca (AZN) vs. GSK (GSK): A comparison of their Debt-to-Equity Ratio (MRQ) against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength at a Glance

SymbolAZNGSK
Current Ratio (MRQ)0.910.79
Debt-to-Equity Ratio (MRQ)0.721.10
Net Debt / EBITDA1.321.37

Dividends

Dividend Yield (TTM)

GSK (GSK) at 3.57% reports Dividend Yield (TTM) in the top quartile of industry peers, ahead of AstraZeneca (AZN) at 1.70%, which sits around the industry mid-range.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.70%

Max
6.57%
Q3
3.18%
Median
1.97%
Q1
0.62%
Min
0.27%

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.57%

Max
6.57%
Q3
3.18%
Median
1.97%
Q1
0.62%
Min
0.27%
AstraZeneca (AZN) vs. GSK (GSK): A comparison of their Dividend Yield (TTM) against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Both AstraZeneca (AZN) at 47.70% and GSK (GSK) at 46.54% post Dividend Payout Ratio (TTM) outside their industries’ typical mid-range — either leaning toward more retention or more distribution than the industry median.

AZN

Pharmaceuticals, Biotechnology & Life Sciences industry group

47.70%

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

46.54%

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
AstraZeneca (AZN) vs. GSK (GSK): A comparison of their Dividend Payout Ratio (TTM) against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividends at a Glance

SymbolAZNGSK
Dividend Yield (TTM)1.70%3.57%
Dividend Payout Ratio (TTM)47.70%46.54%

Performance & Risk

AZN
GSK
Loading price history…
AstraZeneca (AZN) vs. GSK (GSK): Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Performance & Risk at a Glance

SymbolAZNGSK
1-Year Return33.28%31.08%
1-Year Volatility25.45%26.87%
Beta0.250.39
3-Month Avg. Volume1.93M4.18M