AstraZeneca (AZN) vs. GSK (GSK)
This page compares AstraZeneca (AZN) with GSK (GSK) using performance and risk, profitability, financial strength, growth, dividends, and valuation metrics.
Company Profile
AstraZeneca (AZN) and GSK (GSK) are both classified in the Pharmaceuticals sub-industry within the broader Pharmaceuticals industry, placing them in the closest GICS peer bucket.
Both AstraZeneca (AZN, ADR) and GSK (GSK, ADR) trade as depositary receipts or similar foreign-share lines; core company financials may still be comparable, but trading line, FX, program fees, dividend withholding, and home-market rules are worth keeping in view.
| Symbol | AZN | GSK |
|---|---|---|
| Name | AstraZeneca PLC American Depositary Shares | GSK plc Sponsored ADR |
| Country/Region | United Kingdom | United Kingdom |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Pharmaceuticals | Pharmaceuticals |
| GICS Sub-Industry | Pharmaceuticals | Pharmaceuticals |
| Market Capitalization | 287.95 billion USD | 101.38 billion USD |
| Currency | USD | USD |
| Exchange | Nasdaq | NYSE |
| Listing Date | May 12, 1993 | March 28, 1980 |
| Security Type | ADR | ADR |
Valuation
Price-to-Earnings Ratio (TTM)
GSK (GSK) at 13.27 trades in the lower-multiple quartile for Price-to-Earnings Ratio (TTM), while AstraZeneca (AZN) at 27.92 sits around the industry midpoint — GSK has a lower trailing earnings multiple relative to peers, though the gap should be read alongside growth and earnings quality.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
27.92
- Max
- 77.51
- Q3
- 42.45
- Median
- 25.47
- Q1
- 14.64
- Min
- 1.58
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
13.27
- Max
- 77.51
- Q3
- 42.45
- Median
- 25.47
- Q1
- 14.64
- Min
- 1.58
Price-to-Sales Ratio (TTM)
GSK (GSK) at 3.09 sits in the cheaper Price-to-Sales Ratio (TTM) quartile while AstraZeneca (AZN) at 4.76 prices around its industry’s middle — GSK costs less per dollar of sales, though read it alongside growth and margins.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
4.76
- Max
- 60.01
- Q3
- 26.95
- Median
- 6.83
- Q1
- 3.43
- Min
- 0.01
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
3.09
- Max
- 60.01
- Q3
- 26.95
- Median
- 6.83
- Q1
- 3.43
- Min
- 0.01
Price-to-Book Ratio (MRQ)
On Price-to-Book Ratio (MRQ), both AstraZeneca (AZN) at 6.08 and GSK (GSK) at 4.23 are valued close to their industries’ norm against book — neither stands out from peers.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
6.08
- Max
- 12.80
- Q3
- 6.35
- Median
- 3.45
- Q1
- 1.69
- Min
- -4.09
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
4.23
- Max
- 12.80
- Q3
- 6.35
- Median
- 3.45
- Q1
- 1.69
- Min
- -4.09
Valuation at a Glance
| Symbol | AZN | GSK |
|---|---|---|
| Price-to-Earnings Ratio (TTM) | 27.92 | 13.27 |
| Price-to-Sales Ratio (TTM) | 4.76 | 3.09 |
| Price-to-Book Ratio (MRQ) | 6.08 | 4.23 |
| Free Cash Flow Yield | 2.28% | 2.98% |
Profitability
Return on Equity (TTM)
Both AstraZeneca (AZN) at 23.48% and GSK (GSK) at 40.91% rank in the top quartile for Return on Equity (TTM) among industry peers, indicating strong returns on shareholders’ equity.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
23.48%
- Max
- 94.73%
- Q3
- 2.50%
- Median
- -32.62%
- Q1
- -61.80%
- Min
- -157.07%
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
40.91%
- Max
- 94.73%
- Q3
- 2.50%
- Median
- -32.62%
- Q1
- -61.80%
- Min
- -157.07%
Net Profit Margin (TTM)
Both AstraZeneca (AZN) at 17.19% and GSK (GSK) at 17.78% keep an unusually large share of revenue as bottom-line profit — each Net Profit Margin (TTM) clears its industry’s benchmark range.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
17.19%
- Max
- 11.21%
- Q3
- 3.34%
- Median
- 0.00%
- Q1
- -2.04%
- Min
- -9.05%
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
17.78%
- Max
- 11.21%
- Q3
- 3.34%
- Median
- 0.00%
- Q1
- -2.04%
- Min
- -9.05%
Operating Profit Margin (TTM)
Both AstraZeneca (AZN) at 27.94% and GSK (GSK) at 36.28% squeeze more operating profit from each sales dollar than most peers, ranking in the top Operating Profit Margin (TTM) quartile of their industries.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
27.94%
- Max
- 100.30%
- Q3
- 3.47%
- Median
- 0.00%
- Q1
- -138.44%
- Min
- -337.81%
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
36.28%
- Max
- 100.30%
- Q3
- 3.47%
- Median
- 0.00%
- Q1
- -138.44%
- Min
- -337.81%
Profitability at a Glance
| Symbol | AZN | GSK |
|---|---|---|
| Return on Equity (TTM) | 23.48% | 40.91% |
| Return on Assets (TTM) | 8.49% | 10.02% |
| Net Profit Margin (TTM) | 17.19% | 17.78% |
| Operating Profit Margin (TTM) | 27.94% | 36.28% |
| Gross Profit Margin (TTM) | 81.51% | 72.87% |
Growth
Revenue Growth
Revenue Growth at a Glance
| Symbol | AZN | GSK |
|---|---|---|
| 1-Year Revenue Growth | 8.63% | 4.11% |
| 3-Year Revenue CAGR | 9.82% | 3.66% |
EPS Growth
EPS Growth at a Glance
| Symbol | AZN | GSK |
|---|---|---|
| 1-Year EPS Growth | 45.33% | 123.15% |
| 3-Year EPS CAGR | 45.80% | -27.63% |
Financial Strength
Current Ratio (MRQ)
Both AstraZeneca (AZN) at 0.91 and GSK (GSK) at 0.79 run Current Ratio (MRQ) in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.91
- Max
- 24.81
- Q3
- 11.93
- Median
- 5.83
- Q1
- 2.73
- Min
- 0.23
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.79
- Max
- 24.81
- Q3
- 11.93
- Median
- 5.83
- Q1
- 2.73
- Min
- 0.23
Debt-to-Equity Ratio (MRQ)
Both AstraZeneca (AZN) at 0.72 and GSK (GSK) at 1.10 run Debt-to-Equity Ratio (MRQ) in the higher-leverage quartile of industry peers, indicating more debt relative to equity than typical competitors.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.72
- Max
- 1.60
- Q3
- 0.67
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.10
- Max
- 1.60
- Q3
- 0.67
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
Financial Strength at a Glance
| Symbol | AZN | GSK |
|---|---|---|
| Current Ratio (MRQ) | 0.91 | 0.79 |
| Debt-to-Equity Ratio (MRQ) | 0.72 | 1.10 |
| Net Debt / EBITDA | 1.32 | 1.37 |
Dividends
Dividend Yield (TTM)
GSK (GSK) at 3.57% reports Dividend Yield (TTM) in the top quartile of industry peers, ahead of AstraZeneca (AZN) at 1.70%, which sits around the industry mid-range.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.70%
- Max
- 6.57%
- Q3
- 3.18%
- Median
- 1.97%
- Q1
- 0.62%
- Min
- 0.27%
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
3.57%
- Max
- 6.57%
- Q3
- 3.18%
- Median
- 1.97%
- Q1
- 0.62%
- Min
- 0.27%
Dividend Payout Ratio (TTM)
Both AstraZeneca (AZN) at 47.70% and GSK (GSK) at 46.54% post Dividend Payout Ratio (TTM) outside their industries’ typical mid-range — either leaning toward more retention or more distribution than the industry median.
AZN
Pharmaceuticals, Biotechnology & Life Sciences industry group
47.70%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
46.54%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividends at a Glance
| Symbol | AZN | GSK |
|---|---|---|
| Dividend Yield (TTM) | 1.70% | 3.57% |
| Dividend Payout Ratio (TTM) | 47.70% | 46.54% |
Performance & Risk
Performance & Risk at a Glance
| Symbol | AZN | GSK |
|---|---|---|
| 1-Year Return | 33.28% | 31.08% |
| 1-Year Volatility | 25.45% | 26.87% |
| Beta | 0.25 | 0.39 |
| 3-Month Avg. Volume | 1.93M | 4.18M |