ASND vs. VRTX: A Head-to-Head Stock Comparison

Company Overview

VRTX stands out with 111.79 billion USD in market value—about 11.71× ASND’s market cap of 9.55 billion USD.

With betas of 0.40 for ASND and 0.51 for VRTX, both show similar volatility profiles relative to the overall market.

ASND trades as an ADR, giving U.S. investors a simple on-ramp to its foreign shares, while VRTX remains a standard domestic listing.

Performance Comparison

This chart compares the performance of ASND and VRTX over the past year by tracking the growth of an initial $10,000 investment in each (starting one year ago).

Hover over the lines to see the investment’s value and total return (%) at specific dates.

Data is adjusted for dividends and splits.

Valuation Metrics Comparison

The section examines key financial ratios to assess the valuation of ASND and VRTX based on earnings, cash flow, sales, and book value. Pay attention to the following notable points where extreme values stand out.

• Neither ASND nor VRTX turned a profit—both carry negative P/E ratios of -24.55 and -113.09, underscoring continued losses that pressure their valuations.
• Analysts assign negative forward PEG ratios to both ASND (-2.23) and VRTX (-9.08), suggesting expectation of shrinking or negative earnings in the upcoming period—a worrying sign for their profit outlook.
• ASND has a negative P/B ratio of -44.19, indicating its liabilities exceed assets (negative equity). VRTX, with a P/B of 6.78, maintains positive shareholder equity.
• ASND and VRTX both consumed more free cash flow than they generated last year—P/FCF of -27.43 and -88.86, respectively—highlighting persistent liquidity pressure.

Dividend Comparison

Neither ASND nor VRTX currently pays a dividend yield; this often indicates they are reinvesting earnings for growth, prioritizing long-term expansion over immediate cash returns to shareholders.

Financial Strength Metrics Comparison

This section dives into the financial resilience of ASND and VRTX, spotlighting key metrics like liquidity, leverage, and debt coverage. Check out the standout observations below where notable differences or extremes pop up.

• ASND’s quick ratio of 0.71 suggests it may struggle to cover immediate liabilities without selling inventory or raising cash, whereas VRTX at 2.29 maintains a comfortable buffer of liquid assets.
• ASND has negative equity (debt-to-equity ratio -4.46), an unusual warning sign, while VRTX at 0.10 maintains a conventional debt-to-equity balance.
• Both ASND and VRTX report negative interest coverage ratios (-3.72, -32.00), meaning EBIT itself is negative—neither can cover interest, a critical solvency warning.