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ARGX vs. RPRX: A Head-to-Head Stock Comparison

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Here’s a clear look at ARGX and RPRX, comparing key factors like historical performance, profitability, financial strength, growth, dividend, and valuation.

Company Overview

ARGX’s market capitalization of 33.18 billion USD is substantially larger than RPRX’s 20.45 billion USD, indicating a significant difference in their market valuations.

RPRX carries a higher beta at 0.47, indicating it’s more sensitive to market moves, while ARGX (beta: 0.04) exhibits greater stability.

ARGX trades as an American Depositary Receipt (ADR), offering U.S. investors a convenient way to access its foreign-listed shares. In contrast, RPRX is a standard domestic listing.

SymbolARGXRPRX
Company Nameargenx SERoyalty Pharma plc
CountryNLUS
SectorHealthcareHealthcare
IndustryBiotechnologyBiotechnology
CEOTimothy Van Hauwermeiren EMBA,Pablo Gerardo Legorreta
Price543.48 USD36.37 USD
Market Cap33.18 billion USD20.45 billion USD
Beta0.040.47
ExchangeNASDAQNASDAQ
IPO DateMay 18, 2017June 16, 2020
ADRYesNo

Historical Performance

This chart compares the performance of ARGX and RPRX by tracking the growth of an initial $10,000 investment in each. Use the tabs to select the desired time period.

Data is adjusted for dividends and splits.

ARGX vs. RPRX: Growth of a $10,000 investment over the past one year.

Profitability

Return on Equity

ARGX

16.83%

Biotechnology Industry

Max
72.39%
Q3
-6.30%
Median
-32.82%
Q1
-68.26%
Min
-147.61%

In the upper quartile for the Biotechnology industry, ARGX’s Return on Equity of 16.83% signals a highly effective use of shareholder capital to drive profitability compared to most of its peers.

RPRX

16.19%

Biotechnology Industry

Max
72.39%
Q3
-6.30%
Median
-32.82%
Q1
-68.26%
Min
-147.61%

In the upper quartile for the Biotechnology industry, RPRX’s Return on Equity of 16.19% signals a highly effective use of shareholder capital to drive profitability compared to most of its peers.

ARGX vs. RPRX: A comparison of their ROE against the Biotechnology industry benchmark.

Return on Invested Capital

ARGX

-118.38%

Biotechnology Industry

Max
48.74%
Q3
-10.68%
Median
-31.65%
Q1
-52.92%
Min
-113.69%

ARGX has a negative Return on Invested Capital of -118.38%. This indicates that its operations are failing to generate a profit on the total capital invested, signaling significant inefficiency or value destruction.

RPRX

9.56%

Biotechnology Industry

Max
48.74%
Q3
-10.68%
Median
-31.65%
Q1
-52.92%
Min
-113.69%

In the upper quartile for the Biotechnology industry, RPRX’s Return on Invested Capital of 9.56% signifies a highly effective use of its capital to generate profits when compared to its peers.

ARGX vs. RPRX: A comparison of their ROIC against the Biotechnology industry benchmark.

Net Profit Margin

ARGX

37.53%

Biotechnology Industry

Max
87.75%
Q3
-5.05%
Median
-103.44%
Q1
-1,032.77%
Min
-2,366.07%

A Net Profit Margin of 37.53% places ARGX in the upper quartile for the Biotechnology industry, signifying strong profitability and more effective cost management than most of its peers.

RPRX

48.24%

Biotechnology Industry

Max
87.75%
Q3
-5.05%
Median
-103.44%
Q1
-1,032.77%
Min
-2,366.07%

A Net Profit Margin of 48.24% places RPRX in the upper quartile for the Biotechnology industry, signifying strong profitability and more effective cost management than most of its peers.

ARGX vs. RPRX: A comparison of their Net Profit Margin against the Biotechnology industry benchmark.

Operating Profit Margin

ARGX

-1.24%

Biotechnology Industry

Max
87.75%
Q3
-3.28%
Median
-115.26%
Q1
-1,188.86%
Min
-2,943.30%

ARGX has a negative Operating Profit Margin of -1.24%. This signifies the company is unprofitable at the operational level, as its core business expenses exceed its revenue.

RPRX

83.95%

Biotechnology Industry

Max
87.75%
Q3
-3.28%
Median
-115.26%
Q1
-1,188.86%
Min
-2,943.30%

An Operating Profit Margin of 83.95% places RPRX in the upper quartile for the Biotechnology industry. This signals a strong ability to translate revenue into operating profit, outperforming most of its competitors in core business efficiency.

ARGX vs. RPRX: A comparison of their Operating Margin against the Biotechnology industry benchmark.

Profitability at a Glance

SymbolARGXRPRX
Return on Equity (TTM)16.83%16.19%
Return on Assets (TTM)13.45%6.20%
Return on Invested Capital (TTM)-118.38%9.56%
Net Profit Margin (TTM)37.53%48.24%
Operating Profit Margin (TTM)-1.24%83.95%
Gross Profit Margin (TTM)46.33%99.66%

Financial Strength

Current Ratio

ARGX

7.29

Biotechnology Industry

Max
28.73
Q3
13.97
Median
6.31
Q1
3.60
Min
0.02

ARGX’s Current Ratio of 7.29 aligns with the median group of the Biotechnology industry, indicating that its short-term liquidity is in line with its sector peers.

RPRX

1.56

Biotechnology Industry

Max
28.73
Q3
13.97
Median
6.31
Q1
3.60
Min
0.02

RPRX’s Current Ratio of 1.56 falls into the lower quartile for the Biotechnology industry. This indicates a tighter liquidity situation and a more constrained capacity to handle short-term debt than many of its competitors.

ARGX vs. RPRX: A comparison of their Current Ratio against the Biotechnology industry benchmark.

Debt-to-Equity Ratio

ARGX

0.01

Biotechnology Industry

Max
0.46
Q3
0.22
Median
0.06
Q1
0.02
Min
0.00

Falling into the lower quartile for the Biotechnology industry, ARGX’s Debt-to-Equity Ratio of 0.01 points to a conservative financing strategy. This results in lower financial risk but potentially limits strategic investments compared to more leveraged competitors.

RPRX

1.14

Biotechnology Industry

Max
0.46
Q3
0.22
Median
0.06
Q1
0.02
Min
0.00

With a Debt-to-Equity Ratio of 1.14, RPRX operates with exceptionally high leverage compared to the Biotechnology industry norm. This suggests an aggressive reliance on debt financing, which can magnify returns but also significantly elevates financial risk.

ARGX vs. RPRX: A comparison of their D/E Ratio against the Biotechnology industry benchmark.

Interest Coverage Ratio

ARGX

-20.85

Biotechnology Industry

Max
108.32
Q3
-0.55
Median
-8.49
Q1
-74.83
Min
-168.36

ARGX has a negative Interest Coverage Ratio of -20.85. This indicates that its earnings were insufficient to cover even its operational costs, let alone its interest payments, signaling significant financial distress.

RPRX

7.70

Biotechnology Industry

Max
108.32
Q3
-0.55
Median
-8.49
Q1
-74.83
Min
-168.36

RPRX’s Interest Coverage Ratio of 7.70 is in the upper quartile for the Biotechnology industry, signifying a strong and healthy capacity to meet its interest payments from operating profits.

ARGX vs. RPRX: A comparison of their Interest Coverage against the Biotechnology industry benchmark.

Financial Strength at a Glance

SymbolARGXRPRX
Current Ratio (TTM)7.291.56
Quick Ratio (TTM)6.681.56
Debt-to-Equity Ratio (TTM)0.011.14
Debt-to-Asset Ratio (TTM)0.010.43
Net Debt-to-EBITDA Ratio (TTM)-189.752.80
Interest Coverage Ratio (TTM)-20.857.70

Growth

The following charts compare key year-over-year (YoY) growth metrics for ARGX and RPRX. These metrics are based on the companies’ annual financial reports.

Revenue Growth

ARGX vs. RPRX: A comparison of their annual year-over-year Revenue Growth.

Earnings Per Share (EPS) Growth

ARGX vs. RPRX: A comparison of their annual year-over-year Earnings Per Share (EPS) Growth.

Free Cash Flow Growth

ARGX vs. RPRX: A comparison of their annual year-over-year Free Cash Flow Growth.

Dividend

Dividend Yield

ARGX

0.00%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ARGX currently does not pay a dividend, resulting in a yield of 0%. This is a common strategy for growth-focused companies that prioritize reinvesting earnings, though it may be less typical in mature, income-oriented sectors.

RPRX

2.36%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RPRX’s Dividend Yield of 2.36% is exceptionally high, placing it well above the typical range for the Biotechnology industry. While this may seem attractive, an unusually high yield can sometimes be a warning sign, reflecting a falling stock price or market concerns about the dividend’s sustainability.

ARGX vs. RPRX: A comparison of their Dividend Yield against the Biotechnology industry benchmark.

Dividend Payout Ratio

ARGX

0.00%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ARGX has a Dividend Payout Ratio of 0%, indicating it does not currently pay a dividend. This is a common strategy for growth-oriented companies that reinvest all profits back into the business.

RPRX

34.61%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

At 34.61%, RPRX’s Dividend Payout Ratio is exceptionally high, exceeding the typical range for the Biotechnology industry. While this provides a significant return to shareholders, it may limit funds for reinvestment and could be difficult to sustain.

ARGX vs. RPRX: A comparison of their Payout Ratio against the Biotechnology industry benchmark.

Dividend at a Glance

SymbolARGXRPRX
Dividend Yield (TTM)0.00%2.36%
Dividend Payout Ratio (TTM)0.00%34.61%

Valuation

Price-to-Earnings Ratio

ARGX

48.48

Biotechnology Industry

Max
78.44
Q3
48.98
Median
20.50
Q1
12.64
Min
2.14

ARGX’s P/E Ratio of 48.48 is within the middle range for the Biotechnology industry. This suggests its valuation is in line with the sector average, representing neither a significant premium nor a discount compared to its peers.

RPRX

14.43

Biotechnology Industry

Max
78.44
Q3
48.98
Median
20.50
Q1
12.64
Min
2.14

RPRX’s P/E Ratio of 14.43 is within the middle range for the Biotechnology industry. This suggests its valuation is in line with the sector average, representing neither a significant premium nor a discount compared to its peers.

ARGX vs. RPRX: A comparison of their P/E Ratio against the Biotechnology industry benchmark.

Forward P/E to Growth Ratio

ARGX

1.27

Biotechnology Industry

Max
2.29
Q3
1.10
Median
0.49
Q1
0.16
Min
0.02

A Forward PEG Ratio of 1.27 places ARGX in the upper quartile for the Biotechnology industry. This suggests the stock is potentially expensive compared to its peers relative to its growth forecast, which may warrant caution.

RPRX

0.81

Biotechnology Industry

Max
2.29
Q3
1.10
Median
0.49
Q1
0.16
Min
0.02

RPRX’s Forward PEG Ratio of 0.81 is within the middle range of its peers in the Biotechnology industry. This suggests a reasonable balance between the stock’s price and its expected growth, aligning with sector valuation norms.

ARGX vs. RPRX: A comparison of their Forward PEG Ratio against the Biotechnology industry benchmark.

Price-to-Sales Ratio

ARGX

15.66

Biotechnology Industry

Max
110.90
Q3
59.76
Median
11.33
Q1
4.45
Min
0.17

ARGX’s P/S Ratio of 15.66 aligns with the market consensus for the Biotechnology industry. This suggests its valuation, based on sales, is seen as standard and is on par with its competitors.

RPRX

9.03

Biotechnology Industry

Max
110.90
Q3
59.76
Median
11.33
Q1
4.45
Min
0.17

RPRX’s P/S Ratio of 9.03 aligns with the market consensus for the Biotechnology industry. This suggests its valuation, based on sales, is seen as standard and is on par with its competitors.

ARGX vs. RPRX: A comparison of their P/S Ratio against the Biotechnology industry benchmark.

Price-to-Book Ratio

ARGX

7.35

Biotechnology Industry

Max
15.78
Q3
7.44
Median
3.31
Q1
1.58
Min
0.31

The P/B Ratio is often not a primary valuation metric for the Biotechnology industry.

RPRX

2.36

Biotechnology Industry

Max
15.78
Q3
7.44
Median
3.31
Q1
1.58
Min
0.31

The P/B Ratio is often not a primary valuation metric for the Biotechnology industry.

ARGX vs. RPRX: A comparison of their P/B Ratio against the Biotechnology industry benchmark.

Valuation at a Glance

SymbolARGXRPRX
Price-to-Earnings Ratio (P/E, TTM)48.4814.43
Forward PEG Ratio (TTM)1.270.81
Price-to-Sales Ratio (P/S, TTM)15.669.03
Price-to-Book Ratio (P/B, TTM)7.352.36
Price-to-Free Cash Flow Ratio (P/FCF, TTM)-432.727.57
EV-to-EBITDA (TTM)4329.9911.58
EV-to-Sales (TTM)15.0011.92