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APLS vs. ASND: A Head-to-Head Stock Comparison

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Here’s a clear look at APLS and ASND, comparing key factors like historical performance, profitability, financial strength, growth, dividend, and valuation.

Company Profile

APLS is a standard domestic listing, while ASND trades as an American Depositary Receipt (ADR), offering U.S. investors access to its foreign-listed shares.

SymbolAPLSASND
Company NameApellis Pharmaceuticals, Inc.Ascendis Pharma A/S
CountryUnited StatesDenmark
GICS SectorHealth CareHealth Care
GICS IndustryBiotechnologyBiotechnology
Market Capitalization3.36 billion USD11.67 billion USD
ExchangeNasdaqGSNasdaqGS
Listing DateNovember 9, 2017January 28, 2015
Security TypeCommon StockADR

Historical Performance

This chart compares the performance of APLS and ASND by tracking the growth of an initial $10,000 investment in each. Use the tabs to select the desired time period. Data is adjusted for dividends and splits.

APLS vs. ASND: Growth of a $10,000 investment over the past one year.

Historical Performance at a Glance

SymbolAPLSASND
5-Day Price Return-3.77%1.85%
13-Week Price Return50.42%23.49%
26-Week Price Return-3.20%54.29%
52-Week Price Return-31.09%40.18%
Month-to-Date Return18.98%12.17%
Year-to-Date Return-16.70%41.37%
10-Day Avg. Volume2.55M0.65M
3-Month Avg. Volume2.55M0.49M
3-Month Volatility63.36%36.12%
Beta0.710.40

Profitability

Return on Equity (TTM)

APLS

-116.09%

Biotechnology Industry

Max
77.14%
Q3
10.76%
Median
-20.08%
Q1
-42.71%
Min
-119.20%

APLS has a negative Return on Equity of -116.09%. This indicates the company is generating a loss for its shareholders, which can be a result of unprofitability or negative shareholder equity and is often a sign of financial distress.

ASND

-257.14%

Biotechnology Industry

Max
77.14%
Q3
10.76%
Median
-20.08%
Q1
-42.71%
Min
-119.20%

ASND has a negative Return on Equity of -257.14%. This indicates the company is generating a loss for its shareholders, which can be a result of unprofitability or negative shareholder equity and is often a sign of financial distress.

APLS vs. ASND: A comparison of their Return on Equity (TTM) against the Biotechnology industry benchmark.

Net Profit Margin (TTM)

APLS

-30.24%

Biotechnology Industry

Max
59.44%
Q3
16.21%
Median
-11.49%
Q1
-167.42%
Min
-409.07%

APLS has a negative Net Profit Margin of -30.24%, indicating the company is operating at a net loss as its expenses exceeded its revenues.

ASND

-55.25%

Biotechnology Industry

Max
59.44%
Q3
16.21%
Median
-11.49%
Q1
-167.42%
Min
-409.07%

ASND has a negative Net Profit Margin of -55.25%, indicating the company is operating at a net loss as its expenses exceeded its revenues.

APLS vs. ASND: A comparison of their Net Profit Margin (TTM) against the Biotechnology industry benchmark.

Operating Profit Margin (TTM)

APLS

-25.18%

Biotechnology Industry

Max
60.62%
Q3
20.76%
Median
-12.41%
Q1
-181.14%
Min
-482.02%

APLS has a negative Operating Profit Margin of -25.18%. This signifies the company is unprofitable at the operational level, as its core business expenses exceed its revenue.

ASND

-51.66%

Biotechnology Industry

Max
60.62%
Q3
20.76%
Median
-12.41%
Q1
-181.14%
Min
-482.02%

ASND has a negative Operating Profit Margin of -51.66%. This signifies the company is unprofitable at the operational level, as its core business expenses exceed its revenue.

APLS vs. ASND: A comparison of their Operating Profit Margin (TTM) against the Biotechnology industry benchmark.

Profitability at a Glance

SymbolAPLSASND
Return on Equity (TTM)-116.09%-257.14%
Return on Assets (TTM)-26.72%-24.52%
Net Profit Margin (TTM)-30.24%-55.25%
Operating Profit Margin (TTM)-25.18%-51.66%
Gross Profit Margin (TTM)83.78%84.88%

Financial Strength

Current Ratio (MRQ)

APLS

3.77

Biotechnology Industry

Max
19.31
Q3
9.38
Median
4.54
Q1
2.45
Min
0.76

APLS’s Current Ratio of 3.77 aligns with the median group of the Biotechnology industry, indicating that its short-term liquidity is in line with its sector peers.

ASND

1.02

Biotechnology Industry

Max
19.31
Q3
9.38
Median
4.54
Q1
2.45
Min
0.76

ASND’s Current Ratio of 1.02 falls into the lower quartile for the Biotechnology industry. This indicates a tighter liquidity situation and a more constrained capacity to handle short-term debt than many of its competitors.

APLS vs. ASND: A comparison of their Current Ratio (MRQ) against the Biotechnology industry benchmark.

Debt-to-Equity Ratio (MRQ)

APLS

2.90

Biotechnology Industry

Max
1.35
Q3
0.64
Median
0.09
Q1
0.00
Min
0.00

With a Debt-to-Equity Ratio of 2.90, APLS operates with exceptionally high leverage compared to the Biotechnology industry norm. This suggests an aggressive reliance on debt financing, which can magnify returns but also significantly elevates financial risk.

ASND

7.81

Biotechnology Industry

Max
1.35
Q3
0.64
Median
0.09
Q1
0.00
Min
0.00

With a Debt-to-Equity Ratio of 7.81, ASND operates with exceptionally high leverage compared to the Biotechnology industry norm. This suggests an aggressive reliance on debt financing, which can magnify returns but also significantly elevates financial risk.

APLS vs. ASND: A comparison of their Debt-to-Equity Ratio (MRQ) against the Biotechnology industry benchmark.

Interest Coverage Ratio (TTM)

APLS

-5.65

Biotechnology Industry

Max
72.37
Q3
1.91
Median
-7.81
Q1
-63.90
Min
-153.80

APLS has a negative Interest Coverage Ratio of -5.65. This indicates that its earnings were insufficient to cover even its operational costs, let alone its interest payments, signaling significant financial distress.

ASND

-4.54

Biotechnology Industry

Max
72.37
Q3
1.91
Median
-7.81
Q1
-63.90
Min
-153.80

ASND has a negative Interest Coverage Ratio of -4.54. This indicates that its earnings were insufficient to cover even its operational costs, let alone its interest payments, signaling significant financial distress.

APLS vs. ASND: A comparison of their Interest Coverage Ratio (TTM) against the Biotechnology industry benchmark.

Financial Strength at a Glance

SymbolAPLSASND
Current Ratio (MRQ)3.771.02
Quick Ratio (MRQ)3.020.66
Debt-to-Equity Ratio (MRQ)2.907.81
Interest Coverage Ratio (TTM)-5.65-4.54

Growth

Revenue Growth

APLS vs. ASND: A side-by-side comparison of their Revenue Growth for the MRQ (YoY), TTM (YoY), 3-Year CAGR, and 5-Year CAGR periods.

EPS Growth

APLS vs. ASND: A side-by-side comparison of their EPS Growth for the MRQ (YoY), TTM (YoY), 3-Year CAGR, and 5-Year CAGR periods.

Dividend

Dividend Yield (TTM)

APLS

0.00%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

APLS currently does not pay a dividend, resulting in a yield of 0%. This is a common strategy for growth-focused companies that prioritize reinvesting earnings, though it may be less typical in mature, income-oriented sectors.

ASND

0.00%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ASND currently does not pay a dividend, resulting in a yield of 0%. This is a common strategy for growth-focused companies that prioritize reinvesting earnings, though it may be less typical in mature, income-oriented sectors.

APLS vs. ASND: A comparison of their Dividend Yield (TTM) against the Biotechnology industry benchmark.

Dividend Payout Ratio (TTM)

APLS

0.00%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

APLS has a Dividend Payout Ratio of 0%, indicating it does not currently pay a dividend. This is a common strategy for growth-oriented companies that reinvest all profits back into the business.

ASND

0.00%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ASND has a Dividend Payout Ratio of 0%, indicating it does not currently pay a dividend. This is a common strategy for growth-oriented companies that reinvest all profits back into the business.

APLS vs. ASND: A comparison of their Dividend Payout Ratio (TTM) against the Biotechnology industry benchmark.

Dividend at a Glance

SymbolAPLSASND
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

Price-to-Earnings Ratio (TTM)

APLS

--

Biotechnology Industry

Max
60.14
Q3
38.17
Median
29.01
Q1
15.12
Min
0.00

P/E Ratio data for APLS is currently unavailable.

ASND

--

Biotechnology Industry

Max
60.14
Q3
38.17
Median
29.01
Q1
15.12
Min
0.00

P/E Ratio data for ASND is currently unavailable.

APLS vs. ASND: A comparison of their Price-to-Earnings Ratio (TTM) against the Biotechnology industry benchmark.

Price-to-Sales Ratio (TTM)

APLS

4.48

Biotechnology Industry

Max
76.98
Q3
36.53
Median
9.49
Q1
4.49
Min
0.00

In the lower quartile for the Biotechnology industry, APLS’s P/S Ratio of 4.48 indicates its revenue is valued more conservatively than most of its peers. This could present a compelling opportunity if the market has overlooked its sales-generating capabilities.

ASND

20.60

Biotechnology Industry

Max
76.98
Q3
36.53
Median
9.49
Q1
4.49
Min
0.00

ASND’s P/S Ratio of 20.60 aligns with the market consensus for the Biotechnology industry. This suggests its valuation, based on sales, is seen as standard and is on par with its competitors.

APLS vs. ASND: A comparison of their Price-to-Sales Ratio (TTM) against the Biotechnology industry benchmark.

Price-to-Book Ratio (MRQ)

APLS

13.92

Biotechnology Industry

Max
20.53
Q3
9.76
Median
4.77
Q1
2.49
Min
0.59

APLS’s P/B Ratio of 13.92 is in the upper tier for the Biotechnology industry. This indicates that investors are paying a premium relative to the company’s net assets, a valuation that hinges on its ability to generate superior profits.

ASND

67.75

Biotechnology Industry

Max
20.53
Q3
9.76
Median
4.77
Q1
2.49
Min
0.59

At 67.75, ASND’s P/B Ratio is at an extreme premium to the Biotechnology industry. This signifies that the market’s valuation is heavily reliant on future potential rather than its current net asset value, which can be a high-risk proposition.

APLS vs. ASND: A comparison of their Price-to-Book Ratio (MRQ) against the Biotechnology industry benchmark.

Valuation at a Glance

SymbolAPLSASND
Price-to-Earnings Ratio (TTM)----
Price-to-Sales Ratio (TTM)4.4820.60
Price-to-Book Ratio (MRQ)13.9267.75
Price-to-Free Cash Flow Ratio (TTM)58.51--