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AMGN vs. NVS: Amgen vs. Novartis Stock Comparison

How do Amgen (AMGN) and Novartis (NVS) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Amgen (AMGN) and Novartis (NVS) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but AMGN is classified in Biotechnology while NVS is classified in Pharmaceuticals.

Amgen (AMGN) trades as ordinary local shares, while Novartis (NVS) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for Amgen (AMGN) and Novartis (NVS)
Profile ItemAMGNNVS
NameAmgen Inc.Novartis AG Sponsored ADR
Country/RegionUnited StatesSwitzerland
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization236.38 billion USD304.10 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateJune 17, 1983November 7, 1996
Security TypeCommon StockADR

Price Performance

Cumulative Growth

AMGN
NVS
GSPC
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Amgen (AMGN) vs. Novartis (NVS), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Amgen (AMGN) and Novartis (NVS). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Amgen (AMGN) and Novartis (NVS). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Amgen (AMGN) and Novartis (NVS)
MetricAMGNNVS
Total Return (1Y)60.43%28.38%
Total Return (3Y, Annualized)23.06%20.78%
Total Return (5Y, Annualized)17.68%16.11%

Risk Profile

Drawdown History

AMGN
NVS
GSPC
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Amgen (AMGN) vs. Novartis (NVS), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Amgen (AMGN) and Novartis (NVS). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Amgen (AMGN) and Novartis (NVS)
MetricAMGNNVS
Volatility (1Y, Annualized)27.61%22.61%
Beta (5Y)0.410.41
Max Drawdown (5Y)-24.86%-20.42%
Avg. Volume (3M)2.67M1.94M

Risk-Adjusted Performance

Risk-Return Positioning

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AMGN and NVS are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Amgen (AMGN) and Novartis (NVS)
MetricAMGNNVS
Sharpe Ratio (1Y)2.041.07
Sortino Ratio (1Y)3.641.71

Profitability

ROE (TTM)

Both Amgen (AMGN) at 91.47% and Novartis (NVS) at 30.35% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

91.47%

Max
102.29%
AMGN
91.47%
Q3
3.16%
Median
-32.34%
Q1
-64.79%
Min
-157.61%

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

30.35%

Max
102.29%
NVS
30.35%
Q3
3.16%
Median
-32.34%
Q1
-64.79%
Min
-157.61%
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Amgen (AMGN) vs. Novartis (NVS): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Both Amgen (AMGN) at 22.95% and Novartis (NVS) at 22.50% keep an unusually large share of revenue as bottom-line profit — each net margin clears its industry’s benchmark range.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

22.95%

AMGN
22.95%
Max
12.02%
Q3
2.44%
Median
0.00%
Q1
-4.89%
Min
-13.51%

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

22.50%

NVS
22.50%
Max
12.02%
Q3
2.44%
Median
0.00%
Q1
-4.89%
Min
-13.51%
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Amgen (AMGN) vs. Novartis (NVS): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Amgen (AMGN) at 35.55% and Novartis (NVS) at 34.62% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.55%

Max
76.04%
AMGN
35.55%
Q3
10.45%
Median
0.00%
Q1
-120.32%
Min
-308.66%

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

34.62%

Max
76.04%
NVS
34.62%
Q3
10.45%
Median
0.00%
Q1
-120.32%
Min
-308.66%
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Amgen (AMGN) vs. Novartis (NVS): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Amgen (AMGN) and Novartis (NVS)
MetricAMGNNVS
ROE (TTM)91.47%30.35%
ROA (TTM)8.67%10.25%
Net Margin (TTM)22.95%22.50%
Operating Margin (TTM)35.55%34.62%
Gross Margin (TTM)71.89%74.98%

Growth

Revenue Growth

Both Amgen (AMGN) at 9.95% and Novartis (NVS) at 9.57% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Amgen (AMGN) vs. Novartis (NVS): A comparison of their Revenue Growth across different time periods.

EPS Growth

Amgen (AMGN) at 88.23% sits in the top EPS growth quartile, while Novartis (NVS) at 21.81% is closer to the peer norm — faster per-share earnings growth for AMGN.

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Amgen (AMGN) vs. Novartis (NVS): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Amgen (AMGN) and Novartis (NVS)
MetricAMGNNVS
Revenue Growth (YoY)9.95%9.57%
Revenue Growth (3Y CAGR)11.77%9.25%
EPS Growth (YoY)88.23%21.81%
EPS Growth (3Y CAGR)5.52%31.14%

Financial Strength

Current Ratio (MRQ)

Both Amgen (AMGN) at 1.37 and Novartis (NVS) at 0.86 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.37

Max
26.10
Q3
12.34
Median
5.72
Q1
2.80
AMGN
1.37
Min
0.10

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.86

Max
26.10
Q3
12.34
Median
5.72
Q1
2.80
NVS
0.86
Min
0.10
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Amgen (AMGN) vs. Novartis (NVS): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both balance sheets lean debt-heavy versus peers, but AMGN is more stretched: Novartis (NVS) at 1.17 sits in the higher-leverage quartile and Amgen (AMGN) at 4.90 is above its industry benchmark range.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.90

AMGN
4.90
Max
1.56
Q3
0.64
Median
0.14
Q1
0.02
Min
0.00

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.17

Max
1.56
NVS
1.17
Q3
0.64
Median
0.14
Q1
0.02
Min
0.00
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Amgen (AMGN) vs. Novartis (NVS): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Amgen (AMGN) and Novartis (NVS)
MetricAMGNNVS
Current Ratio (MRQ)1.370.86
Debt / Equity (MRQ)4.901.17
Net Debt / EBITDA2.511.79

Dividends

Dividend Yield (TTM)

Both Amgen (AMGN) at 2.21% and Novartis (NVS) at 2.86% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.21%

AMGN
2.21%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.86%

NVS
2.86%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Amgen (AMGN) vs. Novartis (NVS): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Both Amgen (AMGN) at 60.87% and Novartis (NVS) at 71.60% pay out more of their earnings than any of their industry peers — the thinnest cover in their groups, so dividend headroom deserves attention.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

60.87%

AMGN
60.87%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

71.60%

NVS
71.60%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Amgen (AMGN) vs. Novartis (NVS): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Amgen (AMGN) and Novartis (NVS)
MetricAMGNNVS
Dividend Yield (TTM)2.21%2.86%
Dividend Payout Ratio (TTM)60.87%71.60%

Valuation

P/E Ratio (TTM)

Both Amgen (AMGN) at 27.17 and Novartis (NVS) at 24.17 land around their industries’ usual P/E ratio levels — neither is getting a clear earnings-multiple discount or premium versus peers.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

27.17

Max
83.73
Q3
44.68
Median
28.50
AMGN
27.17
Q1
15.51
Min
0.14

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.17

Max
83.73
Q3
44.68
Median
28.50
NVS
24.17
Q1
15.51
Min
0.14
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Amgen (AMGN) vs. Novartis (NVS): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Amgen (AMGN) at 6.21 and Novartis (NVS) at 5.36 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.21

Max
65.27
Q3
29.50
Median
7.31
AMGN
6.21
Q1
3.49
Min
0.01

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.36

Max
65.27
Q3
29.50
Median
7.31
NVS
5.36
Q1
3.49
Min
0.01
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Amgen (AMGN) vs. Novartis (NVS): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Novartis (NVS) at 7.32 sits near its industry’s typical P/B ratio, while Amgen (AMGN) at 20.22 prices above its benchmark range — AMGN looks rich relative to book.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.22

AMGN
20.22
Max
15.46
Q3
7.32
Median
4.02
Q1
1.90
Min
-5.81

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.32

Max
15.46
Q3
7.32
NVS
7.32
Median
4.02
Q1
1.90
Min
-5.81
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Amgen (AMGN) vs. Novartis (NVS): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Amgen (AMGN) and Novartis (NVS)
MetricAMGNNVS
P/E Ratio (TTM)27.1724.17
P/S Ratio (TTM)6.215.36
P/B Ratio (MRQ)20.227.32
Free Cash Flow Yield (TTM)3.66%3.91%