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AMGN vs. NBIX: A Head-to-Head Stock Comparison

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Here’s a clear look at AMGN and NBIX, comparing key factors like historical performance, profitability, financial strength, growth, dividend, and valuation.

Company Overview

AMGN’s market capitalization of 160.37 billion USD is substantially larger than NBIX’s 12.78 billion USD, indicating a significant difference in their market valuations.

AMGN’s beta of 0.50 points to significantly higher volatility compared to NBIX (beta: 0.24), suggesting AMGN has greater potential for both gains and losses relative to market movements.

SymbolAMGNNBIX
Company NameAmgen Inc.Neurocrine Biosciences, Inc.
CountryUSUS
SectorHealthcareHealthcare
IndustryDrug Manufacturers - GeneralDrug Manufacturers - Specialty & Generic
CEORobert A. BradwayKyle W. Gano
Price298.24 USD129.11 USD
Market Cap160.37 billion USD12.78 billion USD
Beta0.500.24
ExchangeNASDAQNASDAQ
IPO DateJune 17, 1983May 23, 1996
ADRNoNo

Historical Performance

This chart compares the performance of AMGN and NBIX by tracking the growth of an initial $10,000 investment in each. Use the tabs to select the desired time period.

Data is adjusted for dividends and splits.

AMGN vs. NBIX: Growth of a $10,000 investment over the past one year.

Profitability

Return on Equity

AMGN

92.94%

Drug Manufacturers - General Industry

Max
95.59%
Q3
76.92%
Median
30.71%
Q1
8.97%
Min
-14.85%

In the upper quartile for the Drug Manufacturers - General industry, AMGN’s Return on Equity of 92.94% signals a highly effective use of shareholder capital to drive profitability compared to most of its peers.

NBIX

11.81%

Drug Manufacturers - Specialty & Generic Industry

Max
51.32%
Q3
9.89%
Median
-3.37%
Q1
-20.99%
Min
-36.07%

In the upper quartile for the Drug Manufacturers - Specialty & Generic industry, NBIX’s Return on Equity of 11.81% signals a highly effective use of shareholder capital to drive profitability compared to most of its peers.

AMGN vs. NBIX: A comparison of their ROE against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Return on Invested Capital

AMGN

9.53%

Drug Manufacturers - General Industry

Max
25.72%
Q3
17.89%
Median
11.47%
Q1
9.39%
Min
2.87%

AMGN’s Return on Invested Capital of 9.53% is in line with the norm for the Drug Manufacturers - General industry, reflecting a standard level of efficiency in generating profits from its capital base.

NBIX

10.31%

Drug Manufacturers - Specialty & Generic Industry

Max
22.54%
Q3
8.45%
Median
1.42%
Q1
-9.01%
Min
-28.41%

In the upper quartile for the Drug Manufacturers - Specialty & Generic industry, NBIX’s Return on Invested Capital of 10.31% signifies a highly effective use of its capital to generate profits when compared to its peers.

AMGN vs. NBIX: A comparison of their ROIC against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Net Profit Margin

AMGN

17.39%

Drug Manufacturers - General Industry

Max
34.51%
Q3
23.04%
Median
14.73%
Q1
11.78%
Min
2.18%

AMGN’s Net Profit Margin of 17.39% is aligned with the median group of its peers in the Drug Manufacturers - General industry. This indicates its ability to convert revenue into profit is typical for the sector.

NBIX

12.68%

Drug Manufacturers - Specialty & Generic Industry

Max
40.33%
Q3
11.92%
Median
-0.45%
Q1
-13.07%
Min
-34.27%

A Net Profit Margin of 12.68% places NBIX in the upper quartile for the Drug Manufacturers - Specialty & Generic industry, signifying strong profitability and more effective cost management than most of its peers.

AMGN vs. NBIX: A comparison of their Net Profit Margin against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Operating Profit Margin

AMGN

21.82%

Drug Manufacturers - General Industry

Max
40.70%
Q3
28.90%
Median
23.41%
Q1
19.05%
Min
16.13%

AMGN’s Operating Profit Margin of 21.82% is around the midpoint for the Drug Manufacturers - General industry, indicating that its efficiency in managing core business operations is typical for the sector.

NBIX

20.61%

Drug Manufacturers - Specialty & Generic Industry

Max
46.91%
Q3
19.02%
Median
6.23%
Q1
-11.23%
Min
-51.89%

An Operating Profit Margin of 20.61% places NBIX in the upper quartile for the Drug Manufacturers - Specialty & Generic industry. This signals a strong ability to translate revenue into operating profit, outperforming most of its competitors in core business efficiency.

AMGN vs. NBIX: A comparison of their Operating Margin against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Profitability at a Glance

SymbolAMGNNBIX
Return on Equity (TTM)92.94%11.81%
Return on Assets (TTM)6.64%8.29%
Return on Invested Capital (TTM)9.53%10.31%
Net Profit Margin (TTM)17.39%12.68%
Operating Profit Margin (TTM)21.82%20.61%
Gross Profit Margin (TTM)63.00%98.25%

Financial Strength

Current Ratio

AMGN

1.17

Drug Manufacturers - General Industry

Max
1.67
Q3
1.37
Median
1.26
Q1
0.87
Min
0.39

AMGN’s Current Ratio of 1.17 aligns with the median group of the Drug Manufacturers - General industry, indicating that its short-term liquidity is in line with its sector peers.

NBIX

3.13

Drug Manufacturers - Specialty & Generic Industry

Max
5.74
Q3
3.37
Median
2.64
Q1
1.73
Min
0.88

NBIX’s Current Ratio of 3.13 aligns with the median group of the Drug Manufacturers - Specialty & Generic industry, indicating that its short-term liquidity is in line with its sector peers.

AMGN vs. NBIX: A comparison of their Current Ratio against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Debt-to-Equity Ratio

AMGN

9.24

Drug Manufacturers - General Industry

Max
2.95
Q3
2.44
Median
0.86
Q1
0.68
Min
0.09

With a Debt-to-Equity Ratio of 9.24, AMGN operates with exceptionally high leverage compared to the Drug Manufacturers - General industry norm. This suggests an aggressive reliance on debt financing, which can magnify returns but also significantly elevates financial risk.

NBIX

0.18

Drug Manufacturers - Specialty & Generic Industry

Max
1.45
Q3
1.06
Median
0.62
Q1
0.13
Min
0.00

NBIX’s Debt-to-Equity Ratio of 0.18 is typical for the Drug Manufacturers - Specialty & Generic industry, indicating its use of leverage is in line with the sector norm. This suggests a balanced approach to its capital structure.

AMGN vs. NBIX: A comparison of their D/E Ratio against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Interest Coverage Ratio

AMGN

3.19

Drug Manufacturers - General Industry

Max
27.46
Q3
14.40
Median
7.80
Q1
4.07
Min
1.67

In the lower quartile for the Drug Manufacturers - General industry, AMGN’s Interest Coverage Ratio of 3.19 indicates a tighter cushion for servicing debt, suggesting less financial flexibility than many of its competitors.

NBIX

--

Drug Manufacturers - Specialty & Generic Industry

Max
10.17
Q3
3.39
Median
0.85
Q1
-2.63
Min
-5.84

Interest Coverage Ratio data for NBIX is currently unavailable.

AMGN vs. NBIX: A comparison of their Interest Coverage against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Financial Strength at a Glance

SymbolAMGNNBIX
Current Ratio (TTM)1.173.13
Quick Ratio (TTM)0.883.02
Debt-to-Equity Ratio (TTM)9.240.18
Debt-to-Asset Ratio (TTM)0.640.12
Net Debt-to-EBITDA Ratio (TTM)3.920.47
Interest Coverage Ratio (TTM)3.19--

Growth

The following charts compare key year-over-year (YoY) growth metrics for AMGN and NBIX. These metrics are based on the companies’ annual financial reports.

Revenue Growth

AMGN vs. NBIX: A comparison of their annual year-over-year Revenue Growth.

Earnings Per Share (EPS) Growth

AMGN vs. NBIX: A comparison of their annual year-over-year Earnings Per Share (EPS) Growth.

Free Cash Flow Growth

AMGN vs. NBIX: A comparison of their annual year-over-year Free Cash Flow Growth.

Dividend

Dividend Yield

AMGN

3.10%

Drug Manufacturers - General Industry

Max
8.72%
Q3
4.10%
Median
3.34%
Q1
1.89%
Min
0.00%

AMGN’s Dividend Yield of 3.10% is consistent with its peers in the Drug Manufacturers - General industry, providing a dividend return that is standard for its sector.

NBIX

0.00%

Drug Manufacturers - Specialty & Generic Industry

Max
9.29%
Q3
0.31%
Median
0.00%
Q1
0.00%
Min
0.00%

NBIX currently does not pay a dividend, resulting in a yield of 0%. This is a common strategy for growth-focused companies that prioritize reinvesting earnings, though it may be less typical in mature, income-oriented sectors.

AMGN vs. NBIX: A comparison of their Dividend Yield against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Dividend Payout Ratio

AMGN

82.64%

Drug Manufacturers - General Industry

Max
266.46%
Q3
78.91%
Median
60.27%
Q1
43.74%
Min
0.00%

AMGN’s Dividend Payout Ratio of 82.64% is in the upper quartile for the Drug Manufacturers - General industry. This indicates a strong commitment to shareholder returns but also suggests that a smaller portion of earnings is retained for reinvestment compared to many peers.

NBIX

0.00%

Drug Manufacturers - Specialty & Generic Industry

Max
125.42%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

NBIX has a Dividend Payout Ratio of 0%, indicating it does not currently pay a dividend. This is a common strategy for growth-oriented companies that reinvest all profits back into the business.

AMGN vs. NBIX: A comparison of their Payout Ratio against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Dividend at a Glance

SymbolAMGNNBIX
Dividend Yield (TTM)3.10%0.00%
Dividend Payout Ratio (TTM)82.64%0.00%

Valuation

Price-to-Earnings Ratio

AMGN

27.04

Drug Manufacturers - General Industry

Max
27.96
Q3
25.84
Median
18.32
Q1
16.65
Min
3.39

A P/E Ratio of 27.04 places AMGN in the upper quartile for the Drug Manufacturers - General industry. This high valuation relative to peers suggests the market holds elevated expectations for the company’s future growth.

NBIX

42.09

Drug Manufacturers - Specialty & Generic Industry

Max
40.89
Q3
28.12
Median
23.94
Q1
18.79
Min
7.76

At 42.09, NBIX’s P/E Ratio is exceptionally high, exceeding the typical maximum for the Drug Manufacturers - Specialty & Generic industry. This suggests the stock may be significantly overvalued compared to its peers and implies high market expectations that could be difficult to meet.

AMGN vs. NBIX: A comparison of their P/E Ratio against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Forward P/E to Growth Ratio

AMGN

7.57

Drug Manufacturers - General Industry

Max
3.10
Q3
3.09
Median
2.72
Q1
2.18
Min
1.02

AMGN’s Forward PEG Ratio of 7.57 is exceptionally high for the Drug Manufacturers - General industry. This suggests its stock price is very high relative to its expected earnings growth, signaling significant overvaluation risk.

NBIX

1.48

Drug Manufacturers - Specialty & Generic Industry

Max
4.19
Q3
2.94
Median
1.47
Q1
0.35
Min
0.00

NBIX’s Forward PEG Ratio of 1.48 is within the middle range of its peers in the Drug Manufacturers - Specialty & Generic industry. This suggests a reasonable balance between the stock’s price and its expected growth, aligning with sector valuation norms.

AMGN vs. NBIX: A comparison of their Forward PEG Ratio against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Price-to-Sales Ratio

AMGN

4.70

Drug Manufacturers - General Industry

Max
6.47
Q3
4.47
Median
3.53
Q1
1.96
Min
0.41

AMGN’s P/S Ratio of 4.70 is in the upper echelon for the Drug Manufacturers - General industry. This means the company is valued richly on its revenue stream compared to its peers, suggesting the stock is priced for a high level of future performance.

NBIX

5.30

Drug Manufacturers - Specialty & Generic Industry

Max
7.49
Q3
4.45
Median
2.12
Q1
1.21
Min
0.25

NBIX’s P/S Ratio of 5.30 is in the upper echelon for the Drug Manufacturers - Specialty & Generic industry. This means the company is valued richly on its revenue stream compared to its peers, suggesting the stock is priced for a high level of future performance.

AMGN vs. NBIX: A comparison of their P/S Ratio against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Price-to-Book Ratio

AMGN

25.85

Drug Manufacturers - General Industry

Max
7.80
Q3
7.80
Median
5.30
Q1
4.06
Min
1.08

The P/B Ratio is often not a primary valuation metric for the Drug Manufacturers - General industry.

NBIX

5.08

Drug Manufacturers - Specialty & Generic Industry

Max
4.93
Q3
3.95
Median
2.14
Q1
1.30
Min
0.13

The P/B Ratio is often not a primary valuation metric for the Drug Manufacturers - Specialty & Generic industry.

AMGN vs. NBIX: A comparison of their P/B Ratio against their respective Drug Manufacturers - General and Drug Manufacturers - Specialty & Generic industry benchmarks.

Valuation at a Glance

SymbolAMGNNBIX
Price-to-Earnings Ratio (P/E, TTM)27.0442.09
Forward PEG Ratio (TTM)7.571.48
Price-to-Sales Ratio (P/S, TTM)4.705.30
Price-to-Book Ratio (P/B, TTM)25.855.08
Price-to-Free Cash Flow Ratio (P/FCF, TTM)14.6925.96
EV-to-EBITDA (TTM)16.8824.14
EV-to-Sales (TTM)6.125.40