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AMGN vs. ARGX: Amgen vs. argenx Stock Comparison

How do Amgen (AMGN) and argenx (ARGX) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Amgen (AMGN) and argenx (ARGX) are both classified in the Biotechnology sub-industry within the broader Biotechnology industry, placing them in the closest GICS peer bucket.

Amgen (AMGN) trades as ordinary local shares, while argenx (ARGX) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for Amgen (AMGN) and argenx (ARGX)
Profile ItemAMGNARGX
NameAmgen Inc. Common Stockargenx SE American Depositary Receipt
Country/RegionUnited StatesNetherlands
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyBiotechnology
GICS Sub-IndustryBiotechnologyBiotechnology
Market Capitalization249.05 billion USD58.31 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateJune 17, 1983May 18, 2017
Security TypeCommon StockADR

Price Performance

Cumulative Growth

AMGN
ARGX
GSPC
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Amgen (AMGN) vs. argenx (ARGX), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Amgen (AMGN) and argenx (ARGX). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Amgen (AMGN) and argenx (ARGX). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Amgen (AMGN) and argenx (ARGX)
MetricAMGNARGX
Total Return (1Y)48.82%11.91%
Total Return (3Y, Annualized)24.31%25.68%
Total Return (5Y, Annualized)20.67%24.22%

Risk Profile

Drawdown History

AMGN
ARGX
GSPC
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Amgen (AMGN) vs. argenx (ARGX), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Amgen (AMGN) and argenx (ARGX). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Amgen (AMGN) and argenx (ARGX)
MetricAMGNARGX
Volatility (1Y, Annualized)29.12%37.87%
Beta (5Y)0.430.45
Max Drawdown (5Y)-24.86%-38.20%
Avg. Volume (3M)2.76M359.84K

Risk-Adjusted Performance

Risk-Return Positioning

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AMGN and ARGX are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Amgen (AMGN) and argenx (ARGX)
MetricAMGNARGX
Sharpe Ratio (1Y)1.530.20
Sortino Ratio (1Y)2.360.31

Profitability

ROE (TTM)

Capital efficiency shows on one side only: Amgen (AMGN) earns 78.35% on shareholders’ equity, ranked against its industry; argenx (ARGX) has no ROE this period.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

78.35%

Max
109.18%
AMGN
78.35%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
ARGX
--
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Amgen (AMGN) vs. argenx (ARGX): ARGX does not report ROE, so it has no value marker; AMGN is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Net Margin (TTM)

Both Amgen (AMGN) at 24.14% and argenx (ARGX) at 31.73% keep an unusually large share of revenue as bottom-line profit — each net margin clears its industry’s benchmark range.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.14%

AMGN
24.14%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

31.73%

ARGX
31.73%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Amgen (AMGN) vs. argenx (ARGX): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Amgen (AMGN) at 35.79% and argenx (ARGX) at 36.27% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.79%

Max
83.12%
AMGN
35.79%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

36.27%

Max
83.12%
ARGX
36.27%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Amgen (AMGN) vs. argenx (ARGX): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Amgen (AMGN) and argenx (ARGX)
MetricAMGNARGX
ROE (TTM)78.35%--
ROA (TTM)8.91%--
Net Margin (TTM)24.14%31.73%
Operating Margin (TTM)35.79%36.27%
Gross Margin (TTM)72.47%59.84%

Growth

Revenue Growth

argenx (ARGX) at 89.64% sits in the top revenue growth quartile, while Amgen (AMGN) at 9.95% is closer to the peer norm — faster top-line expansion for ARGX.

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Amgen (AMGN) vs. argenx (ARGX): A comparison of their Revenue Growth across different time periods.

EPS Growth

Amgen (AMGN) at 88.23% sits in the top EPS growth quartile, while argenx (ARGX) at 53.13% is closer to the peer norm — faster per-share earnings growth for AMGN.

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Amgen (AMGN) vs. argenx (ARGX): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Amgen (AMGN) and argenx (ARGX)
MetricAMGNARGX
Revenue Growth (YoY)9.95%89.64%
Revenue Growth (3Y CAGR)11.77%116.25%
EPS Growth (YoY)88.23%53.13%
EPS Growth (3Y CAGR)5.52%--

Financial Strength

Current Ratio (MRQ)

Short-term liquidity can only be read on one side of this pairing: Amgen (AMGN) shows current ratio of 1.48 against its industry benchmark, while argenx (ARGX) has no reading this period.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.48

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
AMGN
1.48
Min
0.10

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
Min
0.10
ARGX
--
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Amgen (AMGN) vs. argenx (ARGX): ARGX does not report current ratio, so it has no value marker; AMGN is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Debt / Equity (MRQ)

argenx (ARGX) at 0.01 keeps leverage in the lower quartile, while Amgen (AMGN) at 3.76 is above its industry debt-to-equity ratio range.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.76

AMGN
3.76
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.01

Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
ARGX
0.01
Min
0.00
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Amgen (AMGN) vs. argenx (ARGX): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Amgen (AMGN) and argenx (ARGX)
MetricAMGNARGX
Current Ratio (MRQ)1.48--
Debt / Equity (MRQ)3.760.01
Net Debt / EBITDA2.31-2.70

Dividends

Dividend Yield (TTM)

argenx (ARGX) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Amgen (AMGN) reports a yield of 2.16%, ranking against industry peers normally.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.16%

AMGN
2.16%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ARGX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Amgen (AMGN) vs. argenx (ARGX): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

argenx (ARGX) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Amgen (AMGN) reports a payout of 57.62%, ranking against industry peers normally.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

57.62%

AMGN
57.62%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ARGX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Amgen (AMGN) vs. argenx (ARGX): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Amgen (AMGN) and argenx (ARGX)
MetricAMGNARGX
Dividend Yield (TTM)2.16%0.00%
Dividend Payout Ratio (TTM)57.62%0.00%

Valuation

P/E Ratio (TTM)

Both Amgen (AMGN) at 26.69 and argenx (ARGX) at 32.12 land around their industries’ usual P/E ratio levels — neither is getting a clear earnings-multiple discount or premium versus peers.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.69

Max
85.34
Q3
43.46
AMGN
26.69
Median
26.69
Q1
13.30
Min
0.07

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.12

Max
85.34
Q3
43.46
ARGX
32.12
Median
26.69
Q1
13.30
Min
0.07
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Amgen (AMGN) vs. argenx (ARGX): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Amgen (AMGN) at 6.40 and argenx (ARGX) at 9.86 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.40

Max
58.18
Q3
25.77
Median
7.30
AMGN
6.40
Q1
3.01
Min
0.01

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.86

Max
58.18
Q3
25.77
ARGX
9.86
Median
7.30
Q1
3.01
Min
0.01
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Amgen (AMGN) vs. argenx (ARGX): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Measured against book value, both Amgen (AMGN) at 17.35 and argenx (ARGX) at 172.23 look expensive — each P/B ratio sits above its industry’s benchmark range.

AMGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.35

AMGN
17.35
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

ARGX

Pharmaceuticals, Biotechnology & Life Sciences industry group

172.23

ARGX
172.23
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Amgen (AMGN) vs. argenx (ARGX): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Amgen (AMGN) and argenx (ARGX)
MetricAMGNARGX
P/E Ratio (TTM)26.6932.12
P/S Ratio (TTM)6.409.86
P/B Ratio (MRQ)17.35172.23
Free Cash Flow Yield (TTM)2.96%--