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ALNY vs. HUM: A Head-to-Head Stock Comparison

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Here’s a clear look at ALNY and HUM, comparing key factors like historical performance, profitability, financial strength, growth, dividend, and valuation.

Company Overview

ALNY’s market capitalization stands at 43.28 billion USD, while HUM’s is 28.93 billion USD, indicating their market valuations are broadly comparable.

HUM carries a higher beta at 0.43, indicating it’s more sensitive to market moves, while ALNY (beta: 0.21) exhibits greater stability.

SymbolALNYHUM
Company NameAlnylam Pharmaceuticals, Inc.Humana Inc.
CountryUSUS
SectorHealthcareHealthcare
IndustryBiotechnologyMedical - Healthcare Plans
CEOYvonne L. GreenstreetJames A. Rechtin
Price331.91 USD239.68 USD
Market Cap43.28 billion USD28.93 billion USD
Beta0.210.43
ExchangeNASDAQNYSE
IPO DateJune 1, 2004December 31, 1981
ADRNoNo

Historical Performance

This chart compares the performance of ALNY and HUM by tracking the growth of an initial $10,000 investment in each. Use the tabs to select the desired time period.

Data is adjusted for dividends and splits.

ALNY vs. HUM: Growth of a $10,000 investment over the past one year.

Profitability

Return on Equity

ALNY

-509.33%

Biotechnology Industry

Max
72.39%
Q3
-6.30%
Median
-32.82%
Q1
-68.26%
Min
-147.61%

ALNY has a negative Return on Equity of -509.33%. This indicates the company is generating a loss for its shareholders, which can be a result of unprofitability or negative shareholder equity and is often a sign of financial distress.

HUM

10.01%

Medical - Healthcare Plans Industry

Max
13.94%
Q3
13.62%
Median
11.42%
Q1
7.74%
Min
6.98%

HUM’s Return on Equity of 10.01% is on par with the norm for the Medical - Healthcare Plans industry, indicating its profitability relative to shareholder equity is typical for the sector.

ALNY vs. HUM: A comparison of their ROE against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Return on Invested Capital

ALNY

-2.79%

Biotechnology Industry

Max
48.74%
Q3
-10.68%
Median
-31.65%
Q1
-52.92%
Min
-113.69%

ALNY has a negative Return on Invested Capital of -2.79%. This indicates that its operations are failing to generate a profit on the total capital invested, signaling significant inefficiency or value destruction.

HUM

5.69%

Medical - Healthcare Plans Industry

Max
15.50%
Q3
7.12%
Median
5.48%
Q1
-3.47%
Min
-15.02%

HUM’s Return on Invested Capital of 5.69% is in line with the norm for the Medical - Healthcare Plans industry, reflecting a standard level of efficiency in generating profits from its capital base.

ALNY vs. HUM: A comparison of their ROIC against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Net Profit Margin

ALNY

-11.49%

Biotechnology Industry

Max
87.75%
Q3
-5.05%
Median
-103.44%
Q1
-1,032.77%
Min
-2,366.07%

ALNY has a negative Net Profit Margin of -11.49%, indicating the company is operating at a net loss as its expenses exceeded its revenues.

HUM

1.42%

Medical - Healthcare Plans Industry

Max
3.23%
Q3
2.62%
Median
1.70%
Q1
1.27%
Min
1.22%

HUM’s Net Profit Margin of 1.42% is aligned with the median group of its peers in the Medical - Healthcare Plans industry. This indicates its ability to convert revenue into profit is typical for the sector.

ALNY vs. HUM: A comparison of their Net Profit Margin against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Operating Profit Margin

ALNY

-4.91%

Biotechnology Industry

Max
87.75%
Q3
-3.28%
Median
-115.26%
Q1
-1,188.86%
Min
-2,943.30%

ALNY has a negative Operating Profit Margin of -4.91%. This signifies the company is unprofitable at the operational level, as its core business expenses exceed its revenue.

HUM

2.78%

Medical - Healthcare Plans Industry

Max
4.30%
Q3
3.77%
Median
2.61%
Q1
1.60%
Min
-1.64%

HUM’s Operating Profit Margin of 2.78% is around the midpoint for the Medical - Healthcare Plans industry, indicating that its efficiency in managing core business operations is typical for the sector.

ALNY vs. HUM: A comparison of their Operating Margin against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Profitability at a Glance

SymbolALNYHUM
Return on Equity (TTM)-509.33%10.01%
Return on Assets (TTM)-6.40%3.36%
Return on Invested Capital (TTM)-2.79%5.69%
Net Profit Margin (TTM)-11.49%1.42%
Operating Profit Margin (TTM)-4.91%2.78%
Gross Profit Margin (TTM)86.01%100.00%

Financial Strength

Current Ratio

ALNY

3.04

Biotechnology Industry

Max
28.73
Q3
13.97
Median
6.31
Q1
3.60
Min
0.02

ALNY’s Current Ratio of 3.04 falls into the lower quartile for the Biotechnology industry. This indicates a tighter liquidity situation and a more constrained capacity to handle short-term debt than many of its competitors.

HUM

1.91

Medical - Healthcare Plans Industry

Max
1.91
Q3
1.63
Median
1.43
Q1
0.85
Min
0.78

HUM’s Current Ratio of 1.91 is in the upper quartile for the Medical - Healthcare Plans industry. This signifies a strong liquidity position, suggesting the company is well-equipped to cover its immediate liabilities compared to its peers.

ALNY vs. HUM: A comparison of their Current Ratio against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Debt-to-Equity Ratio

ALNY

11.28

Biotechnology Industry

Max
0.46
Q3
0.22
Median
0.06
Q1
0.02
Min
0.00

With a Debt-to-Equity Ratio of 11.28, ALNY operates with exceptionally high leverage compared to the Biotechnology industry norm. This suggests an aggressive reliance on debt financing, which can magnify returns but also significantly elevates financial risk.

HUM

0.75

Medical - Healthcare Plans Industry

Max
1.06
Q3
0.86
Median
0.75
Q1
0.66
Min
0.66

HUM’s Debt-to-Equity Ratio of 0.75 is typical for the Medical - Healthcare Plans industry, indicating its use of leverage is in line with the sector norm. This suggests a balanced approach to its capital structure.

ALNY vs. HUM: A comparison of their D/E Ratio against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Interest Coverage Ratio

ALNY

-0.79

Biotechnology Industry

Max
108.32
Q3
-0.55
Median
-8.49
Q1
-74.83
Min
-168.36

ALNY has a negative Interest Coverage Ratio of -0.79. This indicates that its earnings were insufficient to cover even its operational costs, let alone its interest payments, signaling significant financial distress.

HUM

5.05

Medical - Healthcare Plans Industry

Max
6.23
Q3
6.23
Median
5.19
Q1
4.64
Min
3.18

HUM’s Interest Coverage Ratio of 5.05 is positioned comfortably within the norm for the Medical - Healthcare Plans industry, indicating a standard and healthy capacity to cover its interest payments.

ALNY vs. HUM: A comparison of their Interest Coverage against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Financial Strength at a Glance

SymbolALNYHUM
Current Ratio (TTM)3.041.91
Quick Ratio (TTM)2.981.91
Debt-to-Equity Ratio (TTM)11.280.75
Debt-to-Asset Ratio (TTM)0.310.26
Net Debt-to-EBITDA Ratio (TTM)-1.852.20
Interest Coverage Ratio (TTM)-0.795.05

Growth

The following charts compare key year-over-year (YoY) growth metrics for ALNY and HUM. These metrics are based on the companies’ annual financial reports.

Revenue Growth

ALNY vs. HUM: A comparison of their annual year-over-year Revenue Growth.

Earnings Per Share (EPS) Growth

ALNY vs. HUM: A comparison of their annual year-over-year Earnings Per Share (EPS) Growth.

Free Cash Flow Growth

ALNY vs. HUM: A comparison of their annual year-over-year Free Cash Flow Growth.

Dividend

Dividend Yield

ALNY

0.00%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ALNY currently does not pay a dividend, resulting in a yield of 0%. This is a common strategy for growth-focused companies that prioritize reinvesting earnings, though it may be less typical in mature, income-oriented sectors.

HUM

1.48%

Medical - Healthcare Plans Industry

Max
3.88%
Q3
1.78%
Median
0.73%
Q1
0.00%
Min
0.00%

HUM’s Dividend Yield of 1.48% is consistent with its peers in the Medical - Healthcare Plans industry, providing a dividend return that is standard for its sector.

ALNY vs. HUM: A comparison of their Dividend Yield against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Dividend Payout Ratio

ALNY

0.00%

Biotechnology Industry

Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ALNY has a Dividend Payout Ratio of 0%, indicating it does not currently pay a dividend. This is a common strategy for growth-oriented companies that reinvest all profits back into the business.

HUM

25.15%

Medical - Healthcare Plans Industry

Max
63.88%
Q3
29.91%
Median
12.57%
Q1
0.00%
Min
0.00%

HUM’s Dividend Payout Ratio of 25.15% is within the typical range for the Medical - Healthcare Plans industry, suggesting a balanced approach between shareholder payouts and company reinvestment.

ALNY vs. HUM: A comparison of their Payout Ratio against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Dividend at a Glance

SymbolALNYHUM
Dividend Yield (TTM)0.00%1.48%
Dividend Payout Ratio (TTM)0.00%25.15%

Valuation

Price-to-Earnings Ratio

ALNY

-159.59

Biotechnology Industry

Max
78.44
Q3
48.98
Median
20.50
Q1
12.64
Min
2.14

ALNY has a negative P/E Ratio of -159.59. This occurs when a company has negative earnings (a net loss), making the ratio unsuitable for valuation analysis.

HUM

16.88

Medical - Healthcare Plans Industry

Max
18.17
Q3
17.32
Median
15.48
Q1
13.55
Min
12.84

HUM’s P/E Ratio of 16.88 is within the middle range for the Medical - Healthcare Plans industry. This suggests its valuation is in line with the sector average, representing neither a significant premium nor a discount compared to its peers.

ALNY vs. HUM: A comparison of their P/E Ratio against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Forward P/E to Growth Ratio

ALNY

-43.29

Biotechnology Industry

Max
2.29
Q3
1.10
Median
0.49
Q1
0.16
Min
0.02

ALNY has a negative Forward PEG Ratio of -43.29. This typically results from negative earnings or forecasts of declining future earnings, making the ratio not meaningful for valuation.

HUM

0.80

Medical - Healthcare Plans Industry

Max
1.41
Q3
1.09
Median
0.85
Q1
0.79
Min
0.60

HUM’s Forward PEG Ratio of 0.80 is within the middle range of its peers in the Medical - Healthcare Plans industry. This suggests a reasonable balance between the stock’s price and its expected growth, aligning with sector valuation norms.

ALNY vs. HUM: A comparison of their Forward PEG Ratio against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Price-to-Sales Ratio

ALNY

18.43

Biotechnology Industry

Max
110.90
Q3
59.76
Median
11.33
Q1
4.45
Min
0.17

ALNY’s P/S Ratio of 18.43 aligns with the market consensus for the Biotechnology industry. This suggests its valuation, based on sales, is seen as standard and is on par with its competitors.

HUM

0.24

Medical - Healthcare Plans Industry

Max
0.94
Q3
0.64
Median
0.43
Q1
0.27
Min
0.16

In the lower quartile for the Medical - Healthcare Plans industry, HUM’s P/S Ratio of 0.24 indicates its revenue is valued more conservatively than most of its peers. This could present a compelling opportunity if the market has overlooked its sales-generating capabilities.

ALNY vs. HUM: A comparison of their P/S Ratio against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Price-to-Book Ratio

ALNY

372.86

Biotechnology Industry

Max
15.78
Q3
7.44
Median
3.31
Q1
1.58
Min
0.31

The P/B Ratio is often not a primary valuation metric for the Biotechnology industry.

HUM

1.63

Medical - Healthcare Plans Industry

Max
4.08
Q3
3.83
Median
2.63
Q1
1.74
Min
0.96

HUM’s P/B Ratio of 1.63 is in the lower quartile for the Medical - Healthcare Plans industry. From a value investing perspective, this is favorable, as it suggests the stock is trading at a discount to its net asset value and may offer a greater margin of safety.

ALNY vs. HUM: A comparison of their P/B Ratio against their respective Biotechnology and Medical - Healthcare Plans industry benchmarks.

Valuation at a Glance

SymbolALNYHUM
Price-to-Earnings Ratio (P/E, TTM)-159.5916.88
Forward PEG Ratio (TTM)-43.290.80
Price-to-Sales Ratio (P/S, TTM)18.430.24
Price-to-Book Ratio (P/B, TTM)372.861.63
Price-to-Free Cash Flow Ratio (P/FCF, TTM)-574.0812.15
EV-to-EBITDA (TTM)-285.329.22
EV-to-Sales (TTM)18.550.32