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ALNY vs. BMY: Alnylam Pharmaceuticals vs. Bristol-Myers Squibb Stock Comparison

How do Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ALNY is classified in Biotechnology while BMY is classified in Pharmaceuticals.

Company profile comparison for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY)
Profile ItemALNYBMY
NameAlnylam Pharmaceuticals, Inc.Bristol-Myers Squibb Company
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization20.89 billion USD127.02 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateJune 1, 2004June 1, 1972
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

ALNY
BMY
GSPC
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY)
MetricALNYBMY
Total Return (1Y)-64.57%38.62%
Total Return (3Y, Annualized)-1.58%12.29%
Total Return (5Y, Annualized)-3.13%5.09%

Risk Profile

Drawdown History

ALNY
BMY
GSPC
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY)
MetricALNYBMY
Volatility (1Y, Annualized)54.08%28.01%
Beta (5Y)0.450.19
Max Drawdown (5Y)-68.25%-47.67%
Avg. Volume (3M)1.90M10.85M

Risk-Adjusted Performance

Risk-Return Positioning

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ALNY and BMY are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY)
MetricALNYBMY
Sharpe Ratio (1Y)-1.271.23
Sortino Ratio (1Y)-1.451.95

Profitability

ROE (TTM)

Both companies show strong equity returns, but Alnylam Pharmaceuticals (ALNY) at 138.07% is the standout with ROE above its industry range; Bristol-Myers Squibb (BMY) at 44.01% also sits in the top quartile.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

138.07%

ALNY
138.07%
Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

BMY

Pharmaceuticals, Biotechnology & Life Sciences industry group

44.01%

Max
109.18%
BMY
44.01%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Both Alnylam Pharmaceuticals (ALNY) at 52.85% and Bristol-Myers Squibb (BMY) at 18.47% keep an unusually large share of revenue as bottom-line profit — each net margin clears its industry’s benchmark range.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

52.85%

ALNY
52.85%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

BMY

Pharmaceuticals, Biotechnology & Life Sciences industry group

18.47%

BMY
18.47%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Alnylam Pharmaceuticals (ALNY) at 23.72% and Bristol-Myers Squibb (BMY) at 33.79% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.72%

Max
83.12%
ALNY
23.72%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

BMY

Pharmaceuticals, Biotechnology & Life Sciences industry group

33.79%

Max
83.12%
BMY
33.79%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY)
MetricALNYBMY
ROE (TTM)138.07%44.01%
ROA (TTM)9.51%10.90%
Net Margin (TTM)52.85%18.47%
Operating Margin (TTM)23.72%33.79%
Gross Margin (TTM)77.28%70.50%

Growth

Revenue Growth

Alnylam Pharmaceuticals (ALNY) at 65.19% sits in the top revenue growth quartile, while Bristol-Myers Squibb (BMY) at -0.22% is closer to the peer norm — faster top-line expansion for ALNY.

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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their Revenue Growth across different time periods.

EPS Growth

Neither Alnylam Pharmaceuticals (ALNY) nor Bristol-Myers Squibb (BMY) reports a EPS growth value for this period, so a direct comparison isn't possible.

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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY)
MetricALNYBMY
Revenue Growth (YoY)65.19%-0.22%
Revenue Growth (3Y CAGR)52.98%1.45%
EPS Growth (YoY)----
EPS Growth (3Y CAGR)--5.46%

Financial Strength

Current Ratio (MRQ)

Alnylam Pharmaceuticals (ALNY) at 2.48 keeps current ratio within its industry’s typical mid-range, while Bristol-Myers Squibb (BMY) at 1.59 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for BMY.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.48

Max
25.13
Q3
12.13
Median
5.52
ALNY
2.48
Q1
2.47
Min
0.10

BMY

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.59

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
BMY
1.59
Min
0.10
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both balance sheets lean debt-heavy versus peers, but BMY is more stretched: Alnylam Pharmaceuticals (ALNY) at 0.83 sits in the higher-leverage quartile and Bristol-Myers Squibb (BMY) at 1.91 is above its industry benchmark range.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.83

Max
1.42
ALNY
0.83
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

BMY

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.91

BMY
1.91
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY)
MetricALNYBMY
Current Ratio (MRQ)2.481.59
Debt / Equity (MRQ)0.831.91
Net Debt / EBITDA-0.571.77

Dividends

Dividend Yield (TTM)

Alnylam Pharmaceuticals (ALNY) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Bristol-Myers Squibb (BMY) reports a yield of 3.99%, ranking against industry peers normally.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ALNY
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

BMY

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.99%

BMY
3.99%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Alnylam Pharmaceuticals (ALNY) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Bristol-Myers Squibb (BMY) reports a payout of 55.88%, ranking against industry peers normally.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ALNY
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

BMY

Pharmaceuticals, Biotechnology & Life Sciences industry group

55.88%

BMY
55.88%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY)
MetricALNYBMY
Dividend Yield (TTM)0.00%3.99%
Dividend Payout Ratio (TTM)0.00%55.88%

Valuation

P/E Ratio (TTM)

Alnylam Pharmaceuticals (ALNY) at 7.88 sits in the cheaper P/E ratio quartile, while Bristol-Myers Squibb (BMY) at 13.78 is closer to its industry’s usual earnings multiple — a discount for ALNY, though growth and earnings durability still matter.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.88

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
ALNY
7.88
Min
0.07

BMY

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.78

Max
85.34
Q3
43.46
Median
26.69
BMY
13.78
Q1
13.30
Min
0.07
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

Bristol-Myers Squibb (BMY) at 2.54 sits in the cheaper P/S ratio quartile while Alnylam Pharmaceuticals (ALNY) at 4.17 prices around its industry’s middle — BMY costs less per dollar of sales, though read it alongside growth and margins.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.17

Max
58.18
Q3
25.77
Median
7.30
ALNY
4.17
Q1
3.01
Min
0.01

BMY

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.54

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
BMY
2.54
Min
0.01
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

On P/B ratio, both Alnylam Pharmaceuticals (ALNY) at 5.79 and Bristol-Myers Squibb (BMY) at 5.43 are valued close to their industries’ norm against book — neither stands out from peers.

ALNY

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.79

Max
13.53
Q3
6.54
ALNY
5.79
Median
3.25
Q1
1.69
Min
-5.59

BMY

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.43

Max
13.53
Q3
6.54
BMY
5.43
Median
3.25
Q1
1.69
Min
-5.59
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Alnylam Pharmaceuticals (ALNY) vs. Bristol-Myers Squibb (BMY): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY)
MetricALNYBMY
P/E Ratio (TTM)7.8813.78
P/S Ratio (TTM)4.172.54
P/B Ratio (MRQ)5.795.43
Free Cash Flow Yield (TTM)1.57%5.01%