ALNY vs. BMY: Alnylam Pharmaceuticals vs. Bristol-Myers Squibb Stock Comparison
How do Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Alnylam Pharmaceuticals (ALNY) and Bristol-Myers Squibb (BMY) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ALNY is classified in Biotechnology while BMY is classified in Pharmaceuticals.
| Profile Item | ALNY | BMY |
|---|---|---|
| Name | Alnylam Pharmaceuticals, Inc. | Bristol-Myers Squibb Company |
| Country/Region | United States | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Biotechnology | Pharmaceuticals |
| GICS Sub-Industry | Biotechnology | Pharmaceuticals |
| Market Capitalization | 20.89 billion USD | 127.02 billion USD |
| Currency | USD | USD |
| Exchange | Nasdaq | NYSE |
| Listing Date | June 1, 2004 | June 1, 1972 |
| Security Type | Common Stock | Common Stock |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | ALNY | BMY |
|---|---|---|
| Total Return (1Y) | -64.57% | 38.62% |
| Total Return (3Y, Annualized) | -1.58% | 12.29% |
| Total Return (5Y, Annualized) | -3.13% | 5.09% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
| Metric | ALNY | BMY |
|---|---|---|
| Volatility (1Y, Annualized) | 54.08% | 28.01% |
| Beta (5Y) | 0.45 | 0.19 |
| Max Drawdown (5Y) | -68.25% | -47.67% |
| Avg. Volume (3M) | 1.90M | 10.85M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | ALNY | BMY |
|---|---|---|
| Sharpe Ratio (1Y) | -1.27 | 1.23 |
| Sortino Ratio (1Y) | -1.45 | 1.95 |
Profitability
ROE (TTM)
Both companies show strong equity returns, but Alnylam Pharmaceuticals (ALNY) at 138.07% is the standout with ROE above its industry range; Bristol-Myers Squibb (BMY) at 44.01% also sits in the top quartile.
ALNY
Pharmaceuticals, Biotechnology & Life Sciences industry group
138.07%
- ALNY
- 138.07%
- Max
- 109.18%
- Q3
- 6.23%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
BMY
Pharmaceuticals, Biotechnology & Life Sciences industry group
44.01%
- Max
- 109.18%
- BMY
- 44.01%
- Q3
- 6.23%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
Net Margin (TTM)
Both Alnylam Pharmaceuticals (ALNY) at 52.85% and Bristol-Myers Squibb (BMY) at 18.47% keep an unusually large share of revenue as bottom-line profit — each net margin clears its industry’s benchmark range.
ALNY
Pharmaceuticals, Biotechnology & Life Sciences industry group
52.85%
- ALNY
- 52.85%
- Max
- 18.05%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
BMY
Pharmaceuticals, Biotechnology & Life Sciences industry group
18.47%
- BMY
- 18.47%
- Max
- 18.05%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
Operating Margin (TTM)
Both Alnylam Pharmaceuticals (ALNY) at 23.72% and Bristol-Myers Squibb (BMY) at 33.79% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.
ALNY
Pharmaceuticals, Biotechnology & Life Sciences industry group
23.72%
- Max
- 83.12%
- ALNY
- 23.72%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
BMY
Pharmaceuticals, Biotechnology & Life Sciences industry group
33.79%
- Max
- 83.12%
- BMY
- 33.79%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
Profitability Metrics
| Metric | ALNY | BMY |
|---|---|---|
| ROE (TTM) | 138.07% | 44.01% |
| ROA (TTM) | 9.51% | 10.90% |
| Net Margin (TTM) | 52.85% | 18.47% |
| Operating Margin (TTM) | 23.72% | 33.79% |
| Gross Margin (TTM) | 77.28% | 70.50% |
Growth
Revenue Growth
Alnylam Pharmaceuticals (ALNY) at 65.19% sits in the top revenue growth quartile, while Bristol-Myers Squibb (BMY) at -0.22% is closer to the peer norm — faster top-line expansion for ALNY.
EPS Growth
Neither Alnylam Pharmaceuticals (ALNY) nor Bristol-Myers Squibb (BMY) reports a EPS growth value for this period, so a direct comparison isn't possible.
Growth Metrics
| Metric | ALNY | BMY |
|---|---|---|
| Revenue Growth (YoY) | 65.19% | -0.22% |
| Revenue Growth (3Y CAGR) | 52.98% | 1.45% |
| EPS Growth (YoY) | -- | -- |
| EPS Growth (3Y CAGR) | -- | 5.46% |
Financial Strength
Current Ratio (MRQ)
Alnylam Pharmaceuticals (ALNY) at 2.48 keeps current ratio within its industry’s typical mid-range, while Bristol-Myers Squibb (BMY) at 1.59 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for BMY.
ALNY
Pharmaceuticals, Biotechnology & Life Sciences industry group
2.48
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- ALNY
- 2.48
- Q1
- 2.47
- Min
- 0.10
BMY
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.59
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- BMY
- 1.59
- Min
- 0.10
Debt / Equity (MRQ)
Both balance sheets lean debt-heavy versus peers, but BMY is more stretched: Alnylam Pharmaceuticals (ALNY) at 0.83 sits in the higher-leverage quartile and Bristol-Myers Squibb (BMY) at 1.91 is above its industry benchmark range.
ALNY
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.83
- Max
- 1.42
- ALNY
- 0.83
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
BMY
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.91
- BMY
- 1.91
- Max
- 1.42
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
Financial Strength Metrics
| Metric | ALNY | BMY |
|---|---|---|
| Current Ratio (MRQ) | 2.48 | 1.59 |
| Debt / Equity (MRQ) | 0.83 | 1.91 |
| Net Debt / EBITDA | -0.57 | 1.77 |
Dividends
Dividend Yield (TTM)
Alnylam Pharmaceuticals (ALNY) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Bristol-Myers Squibb (BMY) reports a yield of 3.99%, ranking against industry peers normally.
ALNY
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- ALNY
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
BMY
Pharmaceuticals, Biotechnology & Life Sciences industry group
3.99%
- BMY
- 3.99%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Alnylam Pharmaceuticals (ALNY) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Bristol-Myers Squibb (BMY) reports a payout of 55.88%, ranking against industry peers normally.
ALNY
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- ALNY
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
BMY
Pharmaceuticals, Biotechnology & Life Sciences industry group
55.88%
- BMY
- 55.88%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | ALNY | BMY |
|---|---|---|
| Dividend Yield (TTM) | 0.00% | 3.99% |
| Dividend Payout Ratio (TTM) | 0.00% | 55.88% |
Valuation
P/E Ratio (TTM)
Alnylam Pharmaceuticals (ALNY) at 7.88 sits in the cheaper P/E ratio quartile, while Bristol-Myers Squibb (BMY) at 13.78 is closer to its industry’s usual earnings multiple — a discount for ALNY, though growth and earnings durability still matter.
ALNY
Pharmaceuticals, Biotechnology & Life Sciences industry group
7.88
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- ALNY
- 7.88
- Min
- 0.07
BMY
Pharmaceuticals, Biotechnology & Life Sciences industry group
13.78
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- BMY
- 13.78
- Q1
- 13.30
- Min
- 0.07
P/S Ratio (TTM)
Bristol-Myers Squibb (BMY) at 2.54 sits in the cheaper P/S ratio quartile while Alnylam Pharmaceuticals (ALNY) at 4.17 prices around its industry’s middle — BMY costs less per dollar of sales, though read it alongside growth and margins.
ALNY
Pharmaceuticals, Biotechnology & Life Sciences industry group
4.17
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- ALNY
- 4.17
- Q1
- 3.01
- Min
- 0.01
BMY
Pharmaceuticals, Biotechnology & Life Sciences industry group
2.54
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- Q1
- 3.01
- BMY
- 2.54
- Min
- 0.01
P/B Ratio (MRQ)
On P/B ratio, both Alnylam Pharmaceuticals (ALNY) at 5.79 and Bristol-Myers Squibb (BMY) at 5.43 are valued close to their industries’ norm against book — neither stands out from peers.
ALNY
Pharmaceuticals, Biotechnology & Life Sciences industry group
5.79
- Max
- 13.53
- Q3
- 6.54
- ALNY
- 5.79
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
BMY
Pharmaceuticals, Biotechnology & Life Sciences industry group
5.43
- Max
- 13.53
- Q3
- 6.54
- BMY
- 5.43
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
Valuation Metrics
| Metric | ALNY | BMY |
|---|---|---|
| P/E Ratio (TTM) | 7.88 | 13.78 |
| P/S Ratio (TTM) | 4.17 | 2.54 |
| P/B Ratio (MRQ) | 5.79 | 5.43 |
| Free Cash Flow Yield (TTM) | 1.57% | 5.01% |